Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells A Gómez-Ramos, M Díaz-Hernández, A Rubio, MT Miras-Portugal, J Avila Molecular and Cellular Neuroscience 37 (4), 673-681, 2008 | 277 | 2008 |
Pharmacological inhibition of necroptosis protects from dopaminergic neuronal cell death in Parkinson’s disease models A Iannielli, S Bido, L Folladori, A Segnali, C Cancellieri, A Maresca, ... Cell reports 22 (8), 2066-2079, 2018 | 190 | 2018 |
Rapid conversion of fibroblasts into functional forebrain GABAergic interneurons by direct genetic reprogramming G Colasante, G Lignani, A Rubio, L Medrihan, L Yekhlef, A Sessa, ... Cell stem cell 17 (6), 719-734, 2015 | 177 | 2015 |
Tissue-nonspecific alkaline phosphatase promotes the neurotoxicity effect of extracellular tau M Díaz-Hernández, A Gómez-Ramos, A Rubio, R Gómez-Villafuertes, ... Journal of Biological Chemistry 285 (42), 32539-32548, 2010 | 175 | 2010 |
A human bi-specific antibody against Zika virus with high therapeutic potential J Wang, M Bardelli, DA Espinosa, M Pedotti, TS Ng, S Bianchi, ... Cell 171 (1), 229-241. e15, 2017 | 141 | 2017 |
Characteristics and consequences of muscarinic receptor activation by tau protein A Gómez-Ramos, M Díaz-Hernández, A Rubio, JI Díaz-Hernández, ... European Neuropsychopharmacology 19 (10), 708-717, 2009 | 124 | 2009 |
PRRT2 controls neuronal excitability by negatively modulating Na+ channel 1.2/1.6 activity F Fruscione, P Valente, B Sterlini, A Romei, S Baldassari, M Fadda, ... Brain 141 (4), 1000-1016, 2018 | 114 | 2018 |
Expression of the ghrelin and neurotensin systems is altered in the temporal lobe of Alzheimer's disease patients MD Gahete, A Rubio, J Cordoba-Chacon, F Gracia-Navarro, RD Kineman, ... Journal of Alzheimer's Disease 22 (3), 819-828, 2010 | 111 | 2010 |
Heparin prevents Zika virus induced-cytopathic effects in human neural progenitor cells S Ghezzi, L Cooper, A Rubio, I Pagani, MR Capobianchi, G Ippolito, ... Antiviral research 140, 13-17, 2017 | 101 | 2017 |
Characterization of a double (amyloid precursor protein-tau) transgenic: tau phosphorylation and aggregation M Perez, E Ribe, A Rubio, F Lim, MA Moran, PG Ramos, I Ferrer, MTG Isla, ... Neuroscience 130 (2), 339-347, 2005 | 97 | 2005 |
Expression of Somatostatin, cortistatin, and their receptors, as well as dopamine receptors, but not of neprilysin, are reduced in the temporal lobe of Alzheimer's disease patients MD Gahete, A Rubio, M Durán-Prado, J Avila, RM Luque, JP Castano Journal of Alzheimer's Disease 20 (2), 465-475, 2010 | 85 | 2010 |
Coenzyme A corrects pathological defects in human neurons of PANK 2‐associated neurodegeneration DI Orellana, P Santambrogio, A Rubio, L Yekhlef, C Cancellieri, S Dusi, ... EMBO molecular medicine 8 (10), 1197-1211, 2016 | 81 | 2016 |
SETBP1 induces transcription of a network of development genes by acting as an epigenetic hub R Piazza, V Magistroni, S Redaelli, M Mauri, L Massimino, A Sessa, ... Nature communications 9 (1), 2192, 2018 | 76 | 2018 |
The Numb/p53 circuitry couples replicative self-renewal and tumor suppression in mammary epithelial cells D Tosoni, S Zecchini, M Coazzoli, I Colaluca, G Mazzarol, A Rubio, ... Journal of Cell Biology 211 (4), 845-862, 2015 | 72 | 2015 |
Human endometrial stromal cells are highly permissive to productive infection by Zika virus I Pagani, S Ghezzi, A Ulisse, A Rubio, F Turrini, E Garavaglia, M Candiani, ... Scientific reports 7 (1), 44286, 2017 | 62 | 2017 |
Stem cell modeling of neuroferritinopathy reveals iron as a determinant of senescence and ferroptosis during neuronal aging A Cozzi, DI Orellana, P Santambrogio, A Rubio, C Cancellieri, S Giannelli, ... Stem Cell Reports 13 (5), 832-846, 2019 | 57 | 2019 |
Tau protein role in sleep-wake cycle JL Cantero, E Hita-Yañez, B Moreno-Lopez, F Portillo, A Rubio, J Avila Journal of Alzheimer's Disease 21 (2), 411-421, 2010 | 56 | 2010 |
Rapid and efficient CRISPR/Cas9 gene inactivation in human neurons during human pluripotent stem cell differentiation and direct reprogramming A Rubio, M Luoni, SG Giannelli, I Radice, A Iannielli, C Cancellieri, ... Scientific reports 6 (1), 37540, 2016 | 52 | 2016 |
Comparative study of whole-body MRI and bone scintigraphy for the detection of bone metastases E Balliu, M Boada, I Peláez, JC Vilanova, C Barceló-Vidal, A Rubio, ... Clinical radiology 65 (12), 989-996, 2010 | 49 | 2010 |
Reconstitution of the human nigro-striatal pathway on-a-chip reveals OPA1-dependent mitochondrial defects and loss of dopaminergic synapses A Iannielli, GS Ugolini, C Cordiglieri, S Bido, A Rubio, G Colasante, ... Cell reports 29 (13), 4646-4656. e4, 2019 | 42 | 2019 |