关注
Xin-Yuan Fu
Xin-Yuan Fu
Professor of Biochemistry, NUS, Professor of Immunology Indiana University USA
在 nus.edu.sg 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Function of mitochondrial Stat3 in cellular respiration
J Wegrzyn, R Potla, YJ Chwae, NBV Sepuri, Q Zhang, T Koeck, ...
Science 323 (5915), 793-797, 2009
10452009
Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21WAF1/CIP1 mediated by STAT1
YE Chin, M Kitagawa, WCS Su, ZH You, Y Iwamoto, XY Fu
Science 272 (5262), 719-722, 1996
10051996
Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon alpha.
C Schindler, XINY Fu, T Improta, R Aebersold, JE Darnell Jr
Proceedings of the National Academy of Sciences 89 (16), 7836-7839, 1992
8581992
The proteins of ISGF-3, the interferon alpha-induced transcriptional activator, define a gene family involved in signal transduction.
XY Fu, C Schindler, T Improta, R Aebersold, JE Darnell Jr
Proceedings of the National Academy of Sciences 89 (16), 7840-7843, 1992
7351992
Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis
YE Chin, M Kitagawa, K Kuida, RA Flavell, XY Fu
Molecular and cellular biology 17 (9), 5328-5337, 1997
6821997
ISGF3, the transcriptional activator induced by interferon alpha, consists of multiple interacting polypeptide chains.
XY Fu, DS Kessler, SA Veals, DE Levy, JE Darnell Jr
Proceedings of the National Academy of Sciences 87 (21), 8555-8559, 1990
5671990
A transcription factor with SH2 and SH3 domains is directly activated by an interferon α-induced cytoplasmic protein tyrosine kinase (s)
XY Fu
Cell 70 (2), 323-335, 1992
5151992
Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins
SA Veals, C Schindler, D Leonard, XY Fu, R Aebersold, JE Darnell Jr, ...
Molecular and cellular biology 12 (8), 3315-3324, 1992
5071992
STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity
T Welte, SSM Zhang, T Wang, Z Zhang, DGT Hesslein, Z Yin, A Kano, ...
Proceedings of the National Academy of Sciences 100 (4), 1879-1884, 2003
4812003
Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation
Q Gao, MJ Wolfgang, S Neschen, K Morino, TL Horvath, GI Shulman, ...
Proceedings of the National Academy of Sciences 101 (13), 4661-4666, 2004
4212004
IFN-γ induces cell growth inhibition by Fas-mediated apoptosis: requirement of STAT1 protein for up-regulation of Fas and FasL expression
X Xu, XY Fu, J Plate, ASF Chong
Cancer research 58 (13), 2832-2837, 1998
4181998
Interferon-alpha regulates nuclear translocation and DNA-binding affinity of ISGF3, a multimeric transcriptional activator.
DS Kessler, SA Veals, XY Fu, DE Levy
Genes & development 4 (10), 1753-1765, 1990
4101990
STAT3 is required for Flt3L-dependent dendritic cell differentiation
Y Laouar, T Welte, XY Fu, RA Flavell
Immunity 19 (6), 903-912, 2003
4012003
Transcription factor p91 interacts with the epidermal growth factor receptor and mediates activation of the c-fos gene promoter
XY Fu, JJ Zhang
Cell 74 (6), 1135-1145, 1993
3861993
Cardiomyocyte-restricted knockout of STAT3 results in higher sensitivity to inflammation, cardiac fibrosis, and heart failure with advanced age
JJ Jacoby, A Kalinowski, MG Liu, SSM Zhang, Q Gao, GX Chai, L Ji, ...
Proceedings of the National Academy of Sciences 100 (22), 12929-12934, 2003
3802003
Smad4 signalling in T cells is required for suppression of gastrointestinal cancer
BG Kim, C Li, W Qiao, M Mamura, B Kasperczak, M Anver, L Wolfraim, ...
Nature 441 (7096), 1015-1019, 2006
3562006
Activation of Statl by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism
WCS Su, M Kitagawa, N Xue, B Xie, S Garofalo, J Cho, C Deng, ...
Nature 386 (6622), 288-292, 1997
3441997
A Lys644Glu substitution in fibroblast growth factor receptor 3 (FGFR3) causes dwarfism in mice by activation of STATs and ink4 cell cycle inhibitors
C Li, L Chen, T Iwata, M Kitagawa, XY Fu, CX Deng
Human molecular genetics 8 (1), 35-44, 1999
2641999
Carbon monoxide differentially modulates STAT1 and STAT3 and inhibits apoptosis via a phosphatidylinositol 3-kinase/Akt and p38 kinase-dependent STAT3 pathway during anoxia …
X Zhang, P Shan, J Alam, XY Fu, PJ Lee
Journal of Biological Chemistry 280 (10), 8714-8721, 2005
2272005
ErbB4 signaling in the mammary gland is required for lobuloalveolar development and Stat5 activation during lactation
FE Jones, T Welte, XY Fu, DF Stern
The Journal of cell biology 147 (1), 77-88, 1999
2271999
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