Function of mitochondrial Stat3 in cellular respiration J Wegrzyn, R Potla, YJ Chwae, NBV Sepuri, Q Zhang, T Koeck, ... Science 323 (5915), 793-797, 2009 | 1132 | 2009 |
Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21WAF1/CIP1 mediated by STAT1 YE Chin, M Kitagawa, WCS Su, ZH You, Y Iwamoto, XY Fu Science 272 (5262), 719-722, 1996 | 1025 | 1996 |
Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon alpha. C Schindler, XY Fu, T Improta, R Aebersold, JE Darnell Jr Proceedings of the National Academy of Sciences 89 (16), 7836-7839, 1992 | 876 | 1992 |
The proteins of ISGF-3, the interferon alpha-induced transcriptional activator, define a gene family involved in signal transduction. XY Fu, C Schindler, T Improta, R Aebersold, JE Darnell Jr Proceedings of the National Academy of Sciences 89 (16), 7840-7843, 1992 | 744 | 1992 |
Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis YE Chin, M Kitagawa, K Kuida, RA Flavell, XY Fu Molecular and cellular biology, 1997 | 696 | 1997 |
ISGF3, the transcriptional activator induced by interferon alpha, consists of multiple interacting polypeptide chains. XY Fu, DS Kessler, SA Veals, DE Levy, JE Darnell Jr Proceedings of the National Academy of Sciences 87 (21), 8555-8559, 1990 | 604 | 1990 |
Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins SA Veals, C Schindler, D Leonard, XY Fu, R Aebersold, JE Darnell Jr, ... Molecular and cellular biology 12 (8), 3315-3324, 1992 | 519 | 1992 |
A transcription factor with SH2 and SH3 domains is directly activated by an interferon α-induced cytoplasmic protein tyrosine kinase (s) XY Fu Cell 70 (2), 323-335, 1992 | 518 | 1992 |
STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity T Welte, SSM Zhang, T Wang, Z Zhang, DGT Hesslein, Z Yin, A Kano, ... Proceedings of the National Academy of Sciences 100 (4), 1879-1884, 2003 | 493 | 2003 |
Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation Q Gao, MJ Wolfgang, S Neschen, K Morino, TL Horvath, GI Shulman, ... Proceedings of the National Academy of Sciences 101 (13), 4661-4666, 2004 | 443 | 2004 |
IFN-γ induces cell growth inhibition by Fas-mediated apoptosis: requirement of STAT1 protein for up-regulation of Fas and FasL expression X Xu, XY Fu, J Plate, ASF Chong Cancer research 58 (13), 2832-2837, 1998 | 431 | 1998 |
STAT3 is required for Flt3L-dependent dendritic cell differentiation Y Laouar, T Welte, XY Fu, RA Flavell Immunity 19 (6), 903-912, 2003 | 423 | 2003 |
Interferon-alpha regulates nuclear translocation and DNA-binding affinity of ISGF3, a multimeric transcriptional activator. DS Kessler, SA Veals, XY Fu, DE Levy Genes & development 4 (10), 1753-1765, 1990 | 416 | 1990 |
Cardiomyocyte-restricted knockout of STAT3 results in higher sensitivity to inflammation, cardiac fibrosis, and heart failure with advanced age JJ Jacoby, A Kalinowski, MG Liu, SSM Zhang, Q Gao, GX Chai, L Ji, ... Proceedings of the National Academy of Sciences 100 (22), 12929-12934, 2003 | 399 | 2003 |
Transcription factor p91 interacts with the epidermal growth factor receptor and mediates activation of the c-fos gene promoter XY Fu, JJ Zhang Cell 74 (6), 1135-1145, 1993 | 395 | 1993 |
Smad4 signalling in T cells is required for suppression of gastrointestinal cancer BG Kim, C Li, W Qiao, M Mamura, B Kasperczak, M Anver, L Wolfraim, ... Nature 441 (7096), 1015-1019, 2006 | 382 | 2006 |
Activation of Statl by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism WCS Su, M Kitagawa, N Xue, B Xie, S Garofalo, J Cho, C Deng, ... Nature 386 (6622), 288-292, 1997 | 358 | 1997 |
A Lys644Glu substitution in fibroblast growth factor receptor 3 (FGFR3) causes dwarfism in mice by activation of STATs and ink4 cell cycle inhibitors C Li, L Chen, T Iwata, M Kitagawa, XY Fu, CX Deng Human molecular genetics 8 (1), 35-44, 1999 | 273 | 1999 |
Carbon monoxide differentially modulates STAT1 and STAT3 and inhibits apoptosis via a phosphatidylinositol 3-kinase/Akt and p38 kinase-dependent STAT3 pathway during anoxia … X Zhang, P Shan, J Alam, XY Fu, PJ Lee Journal of Biological Chemistry 280 (10), 8714-8721, 2005 | 235 | 2005 |
ErbB4 signaling in the mammary gland is required for lobuloalveolar development and Stat5 activation during lactation FE Jones, T Welte, XY Fu, DF Stern The Journal of cell biology 147 (1), 77, 1999 | 235 | 1999 |