Protein chemical synthesis by serine and threonine ligation Y Zhang, C Xu, HY Lam, CL Lee, X Li Proceedings of the National Academy of Sciences 110 (17), 6657-6662, 2013 | 267 | 2013 |
Salicylaldehyde ester-induced chemoselective peptide ligations: enabling generation of natural peptidic linkages at the serine/threonine sites X Li, HY Lam, Y Zhang, CK Chan Organic Letters 12 (8), 1724-1727, 2010 | 218 | 2010 |
Ligation technologies for the synthesis of cyclic peptides HY Chow, Y Zhang, E Matheson, X Li Chemical Reviews 119 (17), 9971-10001, 2019 | 178 | 2019 |
New chemistry with old functional groups: on the reaction of isonitriles with carboxylic acids—a route to various amide types X Li, SJ Danishefsky Journal of the American Chemical Society 130 (16), 5446-5448, 2008 | 175 | 2008 |
Total synthesis of daptomycin by cyclization via a chemoselective serine ligation HY Lam, Y Zhang, H Liu, J Xu, CTT Wong, C Xu, X Li Journal of the American Chemical Society 135 (16), 6272-6279, 2013 | 166 | 2013 |
Serine/threonine ligation: origin, mechanistic aspects, and applications H Liu, X Li Accounts of chemical research 51 (7), 1643-1655, 2018 | 142 | 2018 |
Total synthesis of teixobactin K Jin, IH Sam, KHL Po, D Lin, EH Ghazvini Zadeh, S Chen, Y Yuan, X Li Nature communications 7 (1), 12394, 2016 | 134 | 2016 |
Structure of the LpxC deacetylase with a bound substrate-analog inhibitor BE Coggins, X Li, AL McClerren, O Hindsgaul, CRH Raetz, P Zhou Nature Structural & Molecular Biology 10 (8), 645-651, 2003 | 131 | 2003 |
A fascinating journey into history: exploration of the world of isonitriles en route to complex amides RM Wilson, JL Stockdill, X Wu, X Li, PA Vadola, PK Park, P Wang, ... Angewandte Chemie International Edition 51 (12), 2834-2848, 2012 | 128 | 2012 |
Thio FCMA intermediates as strong acyl donors: A general solution to the formation of complex amide bonds Y Rao, X Li, SJ Danishefsky Journal of the American Chemical Society 131 (36), 12924-12926, 2009 | 124 | 2009 |
Biodegradable polylactide/poly (ethylene glycol)/polylactide triblock copolymer micelles as anticancer drug carriers L Liu, C Li, X Li, Z Yuan, Y An, B He Journal of applied polymer science 80 (11), 1976-1982, 2001 | 115 | 2001 |
Chemical protein synthesis: advances, challenges, and outlooks Y Tan, H Wu, T Wei, X Li Journal of the American Chemical Society 142 (48), 20288-20298, 2020 | 104 | 2020 |
Toward fully synthetic homogeneous β-human follicle-stimulating hormone (β-hFSH) with a biantennary N-linked dodecasaccharide. Synthesis of β-hFSH with chitobiose units at the … P Nagorny, B Fasching, X Li, G Chen, B Aussedat, SJ Danishefsky Journal of the American Chemical Society 131 (16), 5792-5799, 2009 | 104 | 2009 |
Synthesis of constrained head-to-tail cyclic tetrapeptides by an imine-induced ring-closing/contraction strategy. CTT Wong, HY Lam, T Song, G Chen, X Li Angewandte Chemie 125 (39), 2013 | 103 | 2013 |
The total synthesis of moenomycin A JG Taylor, X Li, M Oberthür, W Zhu, DE Kahne Journal of the American Chemical Society 128 (47), 15084-15085, 2006 | 102 | 2006 |
Chemoselective peptide cyclization and bicyclization directly on unprotected peptides Y Zhang, Q Zhang, CTT Wong, X Li Journal of the American Chemical Society 141 (31), 12274-12279, 2019 | 101 | 2019 |
The multidrug efflux pump MdtEF protects against nitrosative damage during the anaerobic respiration in Escherichia coli Y Zhang, M Xiao, T Horiyama, Y Zhang, X Li, K Nishino, A Yan Journal of Biological Chemistry 286 (30), 26576-26584, 2011 | 100 | 2011 |
Enabling N-to-C Ser/Thr ligation for convergent protein synthesis via combining chemical ligation approaches CL Lee, H Liu, CTT Wong, HY Chow, X Li Journal of the American Chemical Society 138 (33), 10477-10484, 2016 | 96 | 2016 |
Refined Solution Structure of the LpxC−TU-514 Complex and pKa Analysis of an Active Site Histidine: Insights into the Mechanism and Inhibitor Design, BE Coggins, AL McClerren, L Jiang, X Li, J Rudolph, O Hindsgaul, ... Biochemistry 44 (4), 1114-1126, 2005 | 96 | 2005 |
P− B desulfurization: an enabling method for protein chemical synthesis and site‐specific deuteration K Jin, T Li, HY Chow, H Liu, X Li Angewandte Chemie International Edition 56 (46), 14607-14611, 2017 | 91 | 2017 |