Discovery of a cyclic boronic acid β-lactamase inhibitor (RPX7009) with utility vs class A serine carbapenemases SJ Hecker, KR Reddy, M Totrov, GC Hirst, O Lomovskaya, DC Griffith, ... Journal of medicinal chemistry 58 (9), 3682-3692, 2015 | 427 | 2015 |
Lipocalin 2 promotes breast cancer progression J Yang, DR Bielenberg, SJ Rodig, R Doiron, MC Clifton, AL Kung, ... Proceedings of the National Academy of Sciences 106 (10), 3913-3918, 2009 | 393 | 2009 |
Iron traffics in circulation bound to a siderocalin (Ngal)–catechol complex G Bao, M Clifton, TM Hoette, K Mori, SX Deng, A Qiu, M Viltard, D Williams, ... Nature chemical biology 6 (8), 602-609, 2010 | 357 | 2010 |
Lipocalin 2 is required for pulmonary host defense against Klebsiella infection YR Chan, JS Liu, DA Pociask, M Zheng, TA Mietzner, T Berger, TW Mak, ... The Journal of Immunology 182 (8), 4947-4956, 2009 | 263 | 2009 |
Combining functional and structural genomics to sample the essential Burkholderia structome L Baugh, LA Gallagher, R Patrapuvich, MC Clifton, AS Gardberg, ... PloS one 8 (1), e53851, 2013 | 141 | 2013 |
The Siderocalin/Enterobactin Interaction: A Link between Mammalian Immunity and Bacterial Iron Transport1 RJ Abergel, MC Clifton, JC Pizarro, JA Warner, DK Shuh, RK Strong, ... Journal of the American Chemical Society 130 (34), 11524-11534, 2008 | 131 | 2008 |
Increasing the structural coverage of tuberculosis drug targets L Baugh, I Phan, DW Begley, MC Clifton, B Armour, DM Dranow, ... Tuberculosis 95 (2), 142-148, 2015 | 123 | 2015 |
Siderocalins: siderophore-binding proteins of the innate immune system MC Clifton, C Corrent, RK Strong Biometals 22, 557-564, 2009 | 93 | 2009 |
Siderocalin/Lcn2/NGAL/24p3 does not drive apoptosis through gentisic acid mediated iron withdrawal in hematopoietic cell lines C Correnti, V Richardson, AK Sia, AD Bandaranayake, M Ruiz, ... Public Library of Science 7 (8), e43696, 2012 | 50 | 2012 |
Siderocalin outwits the coordination chemistry of vibriobactin, a siderophore of Vibrio cholerae BE Allred, C Correnti, MC Clifton, RK Strong, KN Raymond ACS chemical biology 8 (9), 1882-1887, 2013 | 46 | 2013 |
Galline Ex-FABP is an antibacterial siderocalin and a lysophosphatidic acid sensor functioning through dual ligand specificities C Correnti, MC Clifton, RJ Abergel, B Allred, TM Hoette, M Ruiz, ... Structure 19 (12), 1796-1806, 2011 | 45 | 2011 |
Discovery and characterization of a selective IKZF2 glue degrader for cancer immunotherapy S Bonazzi, E d’Hennezel, REJ Beckwith, L Xu, A Fazal, A Magracheva, ... Cell Chemical Biology 30 (3), 235-247. e12, 2023 | 40 | 2023 |
A maltose-binding protein fusion construct yields a robust crystallography platform for MCL1 MC Clifton, DM Dranow, A Leed, B Fulroth, JW Fairman, J Abendroth, ... PLoS One 10 (4), e0125010, 2015 | 38 | 2015 |
The structure of a bacterial DUF199/WhiA protein: domestication of an invasive endonuclease BK Kaiser, MC Clifton, BW Shen, BL Stoddard Structure 17 (10), 1368-1376, 2009 | 38 | 2009 |
Immune Interference in Mycobacterium tuberculosis Intracellular Iron Acquisition through Siderocalin Recognition of Carboxymycobactins TM Hoette, MC Clifton, AM Zawadzka, MA Holmes, RK Strong, ... ACS chemical biology 6 (12), 1327-1331, 2011 | 33 | 2011 |
Structure of an ADP-ribosylation factor, ARF1, from Entamoeba histolytica bound to Mg2+–GDP DA Serbzhinskiy, MC Clifton, B Sankaran, BL Staker, TE Edwards, ... Acta Crystallographica Section F: Structural Biology Communications 71 (5 …, 2015 | 31 | 2015 |
Parsing the functional specificity of Siderocalin/Lipocalin 2/NGAL for siderophores and related small-molecule ligands MC Clifton, PB Rupert, TM Hoette, KN Raymond, RJ Abergel, RK Strong Journal of Structural Biology: X 2, 100008, 2019 | 25 | 2019 |
Single diastereomer of a macrolactam core binds specifically to myeloid cell leukemia 1 (MCL1) C Fang, B D’Souza, CF Thompson, MC Clifton, JW Fairman, B Fulroth, ... ACS medicinal chemistry letters 5 (12), 1308-1312, 2014 | 25 | 2014 |
In vitro reassembly of the ribose ATP-binding cassette transporter reveals a distinct set of transport complexes MC Clifton, MJ Simon, SK Erramilli, H Zhang, J Zaitseva, MA Hermodson, ... Journal of Biological Chemistry 290 (9), 5555-5565, 2015 | 21 | 2015 |
NRX-0492 degrades wild-type and C481 mutant BTK and demonstrates in vivo activity in CLL patient-derived xenografts D Zhang, HM Harris, J Chen, J Judy, G James, A Kelly, J McIntosh, ... Blood 141 (13), 1584-1596, 2023 | 19 | 2023 |