Kinetic competition between RNA Polymerase II and Sen1-dependent transcription termination DZ Hazelbaker, S Marquardt, W Wlotzka, S Buratowski Molecular cell 49 (1), 55-66, 2013 | 132 | 2013 |
Distinct RNA degradation pathways and 3'extensions of yeast non-coding RNA species S Marquardt, DZ Hazelbaker, S Buratowski Transcription 2 (3), 145-154, 2011 | 115 | 2011 |
A multiplexed gRNA piggyBac transposon system facilitates efficient induction of CRISPRi and CRISPRa in human pluripotent stem cells DZ Hazelbaker, A Beccard, G Angelini, P Mazzucato, A Messana, D Lam, ... Scientific reports 10 (1), 635, 2020 | 39 | 2020 |
The C-terminal domain of Rpb1 functions on other RNA polymerase II subunits H Suh, DZ Hazelbaker, LM Soares, S Buratowski Molecular cell 51 (6), 850-858, 2013 | 31 | 2013 |
The 22q11. 2 region regulates presynaptic gene-products linked to schizophrenia R Nehme, O Pietiläinen, M Artomov, M Tegtmeyer, V Valakh, L Lehtonen, ... Nature Communications 13 (1), 3690, 2022 | 28 | 2022 |
A scaled framework for CRISPR editing of human pluripotent stem cells to study psychiatric disease DZ Hazelbaker, A Beccard, AM Bara, N Dabkowski, A Messana, ... Stem cell reports 9 (4), 1315-1327, 2017 | 23 | 2017 |
De novo DNA methyltransferases DNMT3A and DNMT3B are essential for XIST silencing for erosion of dosage compensation in pluripotent stem cells A Fukuda, DZ Hazelbaker, N Motosugi, J Hao, F Limone, A Beccard, ... Stem Cell Reports 16 (9), 2138-2148, 2021 | 20 | 2021 |
A biotin interference assay highlights two different asymmetric interaction profiles for λ integrase arm-type binding sites in integrative versus excisive recombination D Hazelbaker, MA Azaro, A Landy Journal of Biological Chemistry 283 (18), 12402-12414, 2008 | 18 | 2008 |
Small-molecule screen reveals pathways that regulate C4 secretion in stem cell-derived astrocytes F Rapino, T Natoli, F Limone, E O’Connor, J Blank, M Tegtmeyer, W Chen, ... Stem Cell Reports 18 (1), 237-253, 2023 | 12 | 2023 |
Receipt of the C-terminal tail from a neighboring λ int protomer allosterically stimulates holliday junction resolution D Hazelbaker, M Radman-Livaja, A Landy Journal of molecular biology 351 (5), 948-955, 2005 | 10 | 2005 |
Critical Role for Saccharomyces cerevisiae Asc1p in Translational Initiation at Elevated Temperatures VR Gerbasi, CM Browne, P Samir, B Shen, M Sun, DZ Hazelbaker, ... Proteomics 18 (23), 1800208, 2018 | 8 | 2018 |
Generation of a TLE1 homozygous knockout human embryonic stem cell line using CRISPR-Cas9 A Herring, A Messana, AM Bara, DZ Hazelbaker, K Eggan, LE Barrett Stem Cell Research 17 (2), 430-432, 2016 | 7 | 2016 |
Generation of a TLE3 heterozygous knockout human embryonic stem cell line using CRISPR-Cas9 AM Bara, A Messana, A Herring, DZ Hazelbaker, K Eggan, LE Barrett Stem Cell Research 17 (2), 441-443, 2016 | 7 | 2016 |
Transcription: base J blocks the way DZ Hazelbaker, S Buratowski Current Biology 22 (22), R960-R962, 2012 | 6 | 2012 |
Molecular convergence between Down syndrome and fragile X syndrome identified using human pluripotent stem cell models SG Susco, S Ghosh, P Mazzucato, G Angelini, A Beccard, V Barrera, ... Cell reports 40 (10), 2022 | 5 | 2022 |
P1429: MULTIPLEX DELETION OF MYELOID ANTIGENS CD33 AND CLL-1 BY CRISPR/CAS9 IN HUMAN HEMATOPOIETIC STEM CELLS HIGHLIGHTS THE POTENTIAL OF NEXT-GENERATION TRANSPLANTS FOR AML … J Xavier-Ferrucio, C Luo, G Angelini, S Krishnamurthy, N Patel, M Pettiglio, ... HemaSphere 6, 1312-1313, 2022 | 2 | 2022 |
Knock out of CD123 or CLL-1 By CRISPR-Cas9 Editing from Human Hematopoietic Stem Cell Transplants Provide New Possibilities for Increasing Therapeutic Index and Safety for AML … C Luo, G Angelini, S Krishnamurthy, J Lisle, M Isik, A Ghdossi, ... Blood 138, 3818, 2021 | 1 | 2021 |
Rigorous Assessment of Off-Target Editing by CRISPR/Cas9 in VOR33, an Engineered Hematopoietic Stem Cell Transplant for the Treatment of Acute Myeloid Leukemia D Hazelbaker, M Isik, A Ghodssi, M Ung, A Halfond, S Wang, K Cummins, ... Molecular Therapy 29 (4), 408-409, 2021 | 1 | 2021 |
VOR33: A Clinic-Ready CRISPR/Cas9 Engineered Hematopoietic Stem Cell Transplant for the Treatment of Acute Myeloid Leukemia J Lydeard, M Lin, C Luo, S Wang, A Halfond, MB Jones, J Scherer, ... Molecular Therapy, 2021 | 1 | 2021 |
Large Serine Integrase Off-target Discovery and Validation for Therapeutic Genome Editing DZ Hazelbaker, JB Mehta, C McGinnis, D Santesmasses, AM Bara, ... bioRxiv, 2024.08. 23.609471, 2024 | | 2024 |