M1-and M2-type macrophage responses are predictive of adverse outcomes in human atherosclerosis M De Gaetano, D Crean, M Barry, O Belton Frontiers in immunology 7, 275, 2016 | 178 | 2016 |
The role of HIF in immunity and inflammation EP Cummins, CE Keogh, D Crean, CT Taylor Molecular aspects of medicine 47, 24-34, 2016 | 157 | 2016 |
Identification and dissection of the Nrf2 mediated oxidative stress pathway in human renal proximal tubule toxicity A Wilmes, D Crean, S Aydin, W Pfaller, P Jennings, MO Leonard Toxicology In Vitro 25 (3), 613-622, 2011 | 102 | 2011 |
Hypoxia and inflammatory bowel disease EP Cummins, D Crean Microbes and infection 19 (3), 210-221, 2017 | 83 | 2017 |
Molecular interactions between NR4A orphan nuclear receptors and NF-κB are required for appropriate inflammatory responses and immune cell homeostasis EP Murphy, D Crean Biomolecules 5 (3), 1302-1318, 2015 | 76 | 2015 |
Lipoxins protect against inflammation in diabetes-associated atherosclerosis EP Brennan, M Mohan, A McClelland, M De Gaetano, C Tikellis, M Marai, ... Diabetes 67 (12), 2657-2667, 2018 | 69 | 2018 |
Liraglutide dictates macrophage phenotype in apolipoprotein E null mice during early atherosclerosis R Bruen, S Curley, S Kajani, D Crean, ME O’Reilly, MB Lucitt, CG Godson, ... Cardiovascular diabetology 16, 1-13, 2017 | 64 | 2017 |
Adenosine modulates NR4A orphan nuclear receptors to attenuate hyperinflammatory responses in monocytic cells D Crean, EP Cummins, B Bahar, H Mohan, JP McMorrow, EP Murphy The Journal of Immunology 195 (4), 1436-1448, 2015 | 58 | 2015 |
Development of an in vitro renal epithelial disease state model for xenobiotic toxicity testing D Crean, P Bellwon, L Aschauer, A Limonciel, K Moenks, P Hewitt, ... Toxicology in Vitro 30 (1), 128-137, 2015 | 44 | 2015 |
Targeting NR4A nuclear receptors to control stromal cell inflammation, metabolism, angiogenesis, and tumorigenesis D Crean, EP Murphy Frontiers in Cell and Developmental Biology 9, 589770, 2021 | 43 | 2021 |
NR4A receptors differentially regulate NF-κB signaling in myeloid cells C McEvoy, M de Gaetano, HE Giffney, B Bahar, EP Cummins, ... Frontiers in Immunology 8, 7, 2017 | 43 | 2017 |
Tumor necrosis factor inhibition modulates thrombospondin-1 expression in human inflammatory joint disease through altered NR4A2 activity JP McMorrow, D Crean, M Gogarty, A Smyth, M Connolly, E Cummins, ... The American Journal of Pathology 183 (4), 1243-1257, 2013 | 35 | 2013 |
Specialised lipid mediators and their targets D Crean, C Godson Seminars in immunology 27 (3), 169-176, 2015 | 33 | 2015 |
HIF hydroxylase inhibitors decrease cellular oxygen consumption depending on their selectivity P Sulser, C Pickel, J Günter, TM Leissing, D Crean, CJ Schofield, ... The FASEB Journal 34 (2), 2344-2358, 2020 | 31 | 2020 |
Interleukin-19 as a translational indicator of renal injury P Jennings, D Crean, L Aschauer, A Limonciel, K Moenks, G Kern, ... Archives of toxicology 89, 101-106, 2015 | 31 | 2015 |
Glucose reintroduction triggers the activation of Nrf2 during experimental ischemia reperfusion D Crean, L Felice, CT Taylor, H Rabb, P Jennings, MO Leonard Molecular and cellular biochemistry 366, 231-238, 2012 | 29 | 2012 |
Histamine contributes to increased RANKL to osteoprotegerin ratio through altered nuclear receptor 4A activity in human chondrocytes V Marzaioli, JP McMorrow, H Angerer, A Gilmore, D Crean, D Zocco, ... Arthritis & Rheumatism 64 (10), 3290-3301, 2012 | 22 | 2012 |
Intra-articular delivery of a nanocomplex comprising salmon calcitonin, hyaluronic acid, and chitosan using an equine model of joint inflammation S Sladek, C Kearney, D Crean, PAJ Brama, L Tajber, K Fawcett, ... Drug delivery and translational research 8, 1421-1435, 2018 | 16 | 2018 |
Modulation of expression in BEAS-2B airway epithelial cells of α-l-fucosidase A1 and A2 by Th1 and Th2 cytokines, and overexpression of α-l-fucosidase 2 AD Sobkowicz, ME Gallagher, CJ Reid, D Crean, SD Carrington, JA Irwin Molecular and cellular biochemistry 390, 101-113, 2014 | 16 | 2014 |
Transcriptional Profiling of Monocytes Deficient in Nuclear Orphan Receptors NR4A2 and NR4A3 Reveals Distinct Signalling Roles Related to Antigen … DE Phelan, M Shigemura, S Aldhafiri, C Mota, TJ Hall, JI Sznajder, ... Frontiers in immunology 12, 676644, 2021 | 12 | 2021 |