Myeloid-derived suppressor cells as a therapeutic target for cancer AMK Law, F Valdes-Mora, D Gallego-Ortega Cells 9 (3), 561, 2020 | 360 | 2020 |
Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis C Vennin, VT Chin, SC Warren, MC Lucas, D Herrmann, A Magenau, ... Science translational medicine 9 (384), eaai8504, 2017 | 243 | 2017 |
Expression of choline kinase alpha to predict outcome in patients with early-stage non-small-cell lung cancer: a retrospective study AR de Molina, J Sarmentero-Estrada, C Belda-Iniesta, M Tarón, ... The lancet oncology 8 (10), 889-897, 2007 | 183 | 2007 |
Progesterone drives mammary secretory differentiation via RankL-mediated induction of Elf5 in luminal progenitor cells HJ Lee, D Gallego-Ortega, A Ledger, D Schramek, P Joshi, MM Szwarc, ... Development 140 (7), 1397-1401, 2013 | 117 | 2013 |
Differential role of human choline kinase α and β enzymes in lipid metabolism: implications in cancer onset and treatment D Gallego-Ortega, A Ramirez de Molina, MA Ramos, F Valdes-Mora, ... PloS one 4 (11), e7819, 2009 | 117 | 2009 |
The innate and adaptive infiltrating immune systems as targets for breast cancer immunotherapy AMK Law, E Lim, CJ Ormandy, D Gallego-Ortega Endocrine-related cancer 24 (4), R123, 2017 | 116 | 2017 |
Droplet-based single cell RNAseq tools: a practical guide R Salomon, D Kaczorowski, F Valdes-Mora, RE Nordon, A Neild, ... Lab on a Chip 19 (10), 1706-1727, 2019 | 104 | 2019 |
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer M Kalyuga, D Gallego-Ortega, HJ Lee, DL Roden, MJ Cowley, CE Caldon, ... PLoS biology 10 (12), e1001461, 2012 | 103 | 2012 |
TWIST1 overexpression is associated with nodal invasion and male sex in primary colorectal cancer F Valdés-Mora, T Gomez del Pulgar, E Bandrés, P Cejas, ... Annals of surgical oncology 16, 78-87, 2009 | 103 | 2009 |
Involvement of Lyn and the atypical kinase SgK269/PEAK1 in a basal breast cancer signaling pathway DR Croucher, F Hochgräfe, L Zhang, L Liu, RJ Lyons, D Rickwood, ... Cancer research 73 (6), 1969-1980, 2013 | 101 | 2013 |
Choline kinase as a link connecting phospholipid metabolism and cell cycle regulation: implications in cancer therapy AR de Molina, D Gallego-Ortega, J Sarmentero-Estrada, D Lagares, ... The international journal of biochemistry & cell biology 40 (9), 1753-1763, 2008 | 101 | 2008 |
Choline kinase is a novel oncogene that potentiates RhoA-induced carcinogenesis A Ramírez de Molina, D Gallego-Ortega, J Sarmentero, M Bañez-Coronel, ... Cancer research 65 (13), 5647-5653, 2005 | 99 | 2005 |
A RhoA-FRET biosensor mouse for intravital imaging in normal tissue homeostasis and disease contexts M Nobis, D Herrmann, SC Warren, S Kadir, W Leung, M Killen, ... Cell reports 21 (1), 274-288, 2017 | 95 | 2017 |
Regulation of Akt (ser473) phosphorylation by choline kinase in breast carcinoma cells BT Chua, D Gallego-Ortega, AR de Molina, A Ullrich, JC Lacal, ... Molecular Cancer 8, 1-12, 2009 | 89 | 2009 |
Temporal profiling of the breast tumour microenvironment reveals collagen XII as a driver of metastasis M Papanicolaou, AL Parker, M Yam, EC Filipe, SZ Wu, JL Chitty, K Wyllie, ... Nature communications 13 (1), 4587, 2022 | 84 | 2022 |
Acetylated histone variant H2A. Z is involved in the activation of neo-enhancers in prostate cancer F Valdés-Mora, CM Gould, Y Colino-Sanguino, W Qu, JZ Song, KM Taylor, ... Nature Communications 8 (1), 1346, 2017 | 83 | 2017 |
MCL-1 inhibition provides a new way to suppress breast cancer metastasis and increase sensitivity to dasatinib AIJ Young, AMK Law, L Castillo, S Chong, HD Cullen, M Koehler, ... Breast Cancer Research 18, 1-15, 2016 | 81 | 2016 |
Single-cell transcriptomics in cancer immunobiology: the future of precision oncology F Valdes-Mora, K Handler, AMK Law, R Salomon, SR Oakes, ... Frontiers in immunology 9, 2582, 2018 | 78 | 2018 |
ELF5 drives lung metastasis in luminal breast cancer through recruitment of Gr1+ CD11b+ myeloid-derived suppressor cells D Gallego-Ortega, A Ledger, DL Roden, AMK Law, A Magenau, ... PLoS biology 13 (12), e1002330, 2015 | 78 | 2015 |
The mammary cellular hierarchy and breast cancer SR Oakes, D Gallego-Ortega, CJ Ormandy Cellular and Molecular Life Sciences 71, 4301-4324, 2014 | 74 | 2014 |