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Mohamad Kourghi
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Non‐selective cation channel activity of aquaporin AtPIP2;1 regulated by Ca2+ and pH
CS Byrt, M Zhao, M Kourghi, J Bose, SW Henderson, J Qiu, M Gilliham, ...
Plant, cell & environment 40 (6), 802-815, 2017
1902017
Divalent cations regulate the ion conductance properties of diverse classes of aquaporins
M Kourghi, S Nourmohammadi, JV Pei, J Qiu, S McGaughey, SD Tyerman, ...
International journal of molecular sciences 18 (11), 2323, 2017
722017
Bumetanide derivatives AqB007 and AqB011 selectively block the aquaporin-1 ion channel conductance and slow cancer cell migration
M Kourghi, JV Pei, ML De Ieso, G Flynn, AJ Yool
Molecular pharmacology 89 (1), 133-140, 2016
702016
Differential inhibition of water and ion channel activities of mammalian aquaporin-1 by two structurally related bacopaside compounds derived from the medicinal plant Bacopa …
JV Pei, M Kourghi, ML De Ieso, EM Campbell, HS Dorward, ...
Molecular pharmacology 90 (4), 496-507, 2016
632016
Fundamental structural and functional properties of Aquaporin ion channels found across the kingdoms of life
M Kourghi, JV Pei, ML De Ieso, S Nourmohammadi, PH Chow, AJ Yool
Clinical and Experimental Pharmacology and Physiology 45 (4), 401-409, 2018
472018
Combined pharmacological administration of AQP1 ion channel blocker AqB011 and water channel blocker Bacopaside II amplifies inhibition of colon cancer cell migration
ML De Ieso, JV Pei, S Nourmohammadi, E Smith, PH Chow, M Kourghi, ...
Scientific reports 9 (1), 12635, 2019
402019
5-hydroxymethyl-furfural and structurally related compounds block the ion conductance in human aquaporin-1 channels and slow cancer cell migration and invasion
PH Chow, M Kourghi, JV Pei, S Nourmohammadi, AJ Yool
Molecular Pharmacology 98 (1), 38-48, 2020
282020
Identification of loop D domain amino acids in the human Aquaporin-1 channel involved in activation of the ionic conductance and inhibition by AqB011
M Kourghi, ML De Ieso, S Nourmohammadi, JV Pei, AJ Yool
Frontiers in chemistry 6, 142, 2018
262018
Development of a photoswitchable lithium-sensitive probe to analyze nonselective cation channel activity in migrating cancer cells
JV Pei, S Heng, ML De Ieso, G Sylvia, M Kourghi, S Nourmohammadi, ...
Molecular Pharmacology 95 (5), 573-583, 2019
222019
Drug discovery and therapeutic targets for pharmacological modulators of aquaporin channels
JV Pei, JL Burton, M Kourghi, ML De Ieso, AJ Yool
Aquaporins in Health and Disease: New Molecular Targets For Drug Discovery …, 2016
112016
Lithium'Hot-spots': Real-time Analysis of non-selective cation channel activity in migrating cancer cells
JV Pei, S Heng, ML De Ieso, GM Sylvia, M Kourghi, S Nourmohammadi, ...
Molecular Pharmacology, 2019
22019
Furan compounds that are effective in preventing red blood cell sickling inhibit the Aquaporin-1 ion conductance
PH Chow, M Kourghi, JV Pei, AJ Yool
Role of Aquaporin1 in Diseases and Drug Discovery, 168, 2020
2020
Lithium ‘Hot-spots’: Real-time Analysis of Ion Conductance in Aquaporin-1
JV Pei, S Heng, M De Ieso, GM Sylvia, M Kourghi, S Nourmohammadi, ...
Sensing in Biological Systems, 128, 2018
2018
Real-Time Imaging of Lithium ‘Hot-Spots’: An Analysis of Ion Conductance in Aquaporin-1 using Novel Photo-Switchable Sensor
JV Pei, S Heng, M De Ieso, G Sylvia, M Kourghi, AD Abell, AJ Yool
Biophysical Journal 114 (3), 360a, 2018
2018
Drug Discovery and Therapeutic Targets for Pharmacological Modulators of Aquaporin Channels
AJY Jinxin Victor Pei, Joshua Luke Burton, Mohamad Kourghi, Michael L De Ieso
Aquaporins in Health and Disease: New Molecular Targets for Drug Discovery 1, 2015
2015
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