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Jordy Homing Lam
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Structural basis of the activation of a metabotropic GABA receptor
H Shaye, A Ishchenko, JH Lam, GW Han, L Xue, P Rondard, JP Pin, ...
Nature 584 (7820), 298-303, 2020
1082020
A deep learning framework to predict binding preference of RNA constituents on protein surface
JH Lam, Y Li, L Zhu, R Umarov, H Jiang, A Héliou, FK Sheong, T Liu, ...
Nature communications 10 (1), 4941, 2019
892019
Self-assembling tetrameric peptides allow in situ 3D bioprinting under physiological conditions
S Rauf, HH Susapto, K Kahin, S Alshehri, S Abdelrahman, JH Lam, ...
Journal of Materials Chemistry B 9 (4), 1069-1081, 2021
562021
Structural basis of GABA reuptake inhibition
Z Motiwala, NG Aduri, H Shaye, GW Han, JH Lam, V Katritch, V Cherezov, ...
Nature 606 (7915), 820-826, 2022
522022
Ligand and G-protein selectivity in the κ-opioid receptor
J Han, J Zhang, AL Nazarova, SM Bernhard, BE Krumm, L Zhao, JH Lam, ...
Nature 617 (7960), 417-425, 2023
312023
Structural details of a Class B GPCR-arrestin complex revealed by genetically encoded crosslinkers in living cells
Y Aydin, T Böttke, JH Lam, S Ernicke, A Fortmann, M Tretbar, B Zarzycka, ...
Nature Communications 14 (1), 1151, 2023
212023
Structure of the full-length human Pannexin1 channel and insights into its role in pyroptosis
S Zhang, B Yuan, JH Lam, J Zhou, X Zhou, G Ramos-Mandujano, X Tian, ...
Cell Discovery 7 (1), 30, 2021
192021
Constitutive activation mechanism of a class C GPCR
J Shin, J Park, J Jeong, JH Lam, X Qiu, D Wu, K Kim, JY Lee, ...
Nature Structural & Molecular Biology 31 (4), 678-687, 2024
22024
The Functional Diversity of G Proteins in Opioid Receptor Signaling
T Che, Q Jiang, J Han, J Zhang, A Nazarova, SM Bernhard, BE Krumm, ...
Journal of Pharmacology and Experimental Therapeutics 389 (S3), 2024
2024
Efficacy modulation by targeting the sodium binding allosteric site in the delta opioid receptor
BR Varga, SM Bernhard, A El Daibani, S Zaidi, J Aquilar, A Nazarova, ...
Journal of Pharmacology and Experimental Therapeutics 389 (S3), 2024
2024
Scalable computation of anisotropic vibrations for large macromolecular assemblies
JH Lam, A Nakano, V Katritch
Nature Communications 15 (1), 3479, 2024
2024
Structure, Function, and Pharmacology of Delta Opioid Receptor Bitopics
S Bernhard, BR Varga, A El Daibani, JH Lam, S Zaidi, K Appourchaux, ...
Journal of Pharmacology and Experimental Therapeutics 385 (S3), 2023
2023
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