High-affinity oligoclonal TCRs define effective adoptive T cell therapy targeting mutant KRAS-G12D MJW Sim, J Lu, M Spencer, F Hopkins, E Tran, SA Rosenberg, EO Long, ... Proceedings of the National Academy of Sciences 117 (23), 12826-12835, 2020 | 89 | 2020 |
Human NK cell receptor KIR2DS4 detects a conserved bacterial epitope presented by HLA-C MJW Sim, S Rajagopalan, DM Altmann, RJ Boyton, PD Sun, EO Long Proceedings of the National Academy of Sciences 116 (26), 12964-12973, 2019 | 79 | 2019 |
Lung defense through IL-8 carries a cost of chronic lung remodeling and impaired function CJ Reynolds, K Quigley, X Cheng, A Suresh, S Tahir, F Ahmed-Jushuf, ... American journal of respiratory cell and molecular biology 59 (5), 557-571, 2018 | 60 | 2018 |
Canonical and cross-reactive binding of NK cell inhibitory receptors to HLA-C allotypes is dictated by peptides bound to HLA-C MJW Sim, SA Malaker, A Khan, JM Stowell, J Shabanowitz, ME Peterson, ... Frontiers in immunology 8, 193, 2017 | 50 | 2017 |
KIR2DL3 and KIR2DL1 show similar impact on licensing of human NK cells MJW Sim, J Stowell, R Sergeant, DM Altmann, EO Long, RJ Boyton European journal of immunology 46 (1), 185-191, 2016 | 30 | 2016 |
Innate Immunity in multiple sclerosis white matter lesions: expression of natural cytotoxicity triggering receptor 1 (NCR1) PF Durrenberger, A Ettorre, F Kamel, LV Webb, M Sim, RS Nicholas, ... Journal of neuroinflammation 9, 1-14, 2012 | 30 | 2012 |
Increased HLA‐E expression in white matter lesions in multiple sclerosis PF Durrenberger, LV Webb, MJW Sim, RS Nicholas, DM Altmann, ... Immunology 137 (4), 317-325, 2012 | 28 | 2012 |
T cell recognition of tumor neoantigens and insights into T cell immunotherapy MJW Sim, P Sun Frontiers in Immunology, 384, 2022 | 26 | 2022 |
HLA-F: a new kid licensed for peptide presentation MJW Sim, PD Sun Immunity 46 (6), 972-974, 2017 | 12 | 2017 |
A single amino acid change in inhibitory killer cell Ig-like receptor results in constitutive receptor self-association and phosphorylation S Kumar, P Sarkar, MJW Sim, S Rajagopalan, SS Vogel, EO Long The Journal of Immunology 194 (2), 817-826, 2015 | 12 | 2015 |
Innate receptors with high specificity for HLA class I–peptide complexes MJW Sim, P Brennan, KL Wahl, J Lu, S Rajagopalan, PD Sun, EO Long Science Immunology 8 (87), 2023 | 9 | 2023 |
T cells discriminate between groups C1 and C2 HLA-C MJW Sim, Z Stotz, J Lu, P Brennan, EO Long, PD Sun Elife 11, e75670, 2022 | 8 | 2022 |
Autoantigen cross-reactive environmental antigen can trigger multiple sclerosis-like disease CJ Reynolds, MJW Sim, KJ Quigley, DM Altmann, RJ Boyton Journal of Neuroinflammation 12, 1-5, 2015 | 5 | 2015 |
TCRs and AI: the future is now MJW Sim Nature Reviews Immunology 24 (1), 3-3, 2024 | 2 | 2024 |
Identification and structural characterization of a mutant KRAS‐G12V specific TCR restricted by HLA‐A3 MJW Sim, K Hanada, Z Stotz, Z Yu, J Lu, P Brennan, M Quastel, ... European Journal of Immunology, 2451079, 2024 | | 2024 |
The influence of HLA-C and KIR on natural killer cell function MJW Sim Imperial College London, 2016 | | 2016 |