Emerging mechanisms of molecular pathology in ALS OM Peters, M Ghasemi, RH Brown The Journal of clinical investigation 125 (5), 1767-1779, 2015 | 377 | 2015 |
Human C9ORF72 hexanucleotide expansion reproduces RNA foci and dipeptide repeat proteins but not neurodegeneration in BAC transgenic mice OM Peters, GT Cabrera, H Tran, TF Gendron, JE McKeon, J Metterville, ... Neuron 88 (5), 902-909, 2015 | 295 | 2015 |
TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD MA White, E Kim, A Duffy, R Adalbert, BU Phillips, OM Peters, ... Nature neuroscience 21 (4), 552-563, 2018 | 251 | 2018 |
Functional alterations to the nigrostriatal system in mice lacking all three members of the synuclein family S Anwar, O Peters, S Millership, N Ninkina, N Doig, N Connor-Robson, ... Journal of Neuroscience 31 (20), 7264-7274, 2011 | 239 | 2011 |
Autophagic and endo-lysosomal dysfunction in neurodegenerative disease BR Malik, DC Maddison, GA Smith, OM Peters Molecular brain 12 (1), 100, 2019 | 156 | 2019 |
Fused in Sarcoma (FUS) Protein Lacking Nuclear Localization Signal (NLS) and Major RNA Binding Motifs Triggers Proteinopathy and Severe Motor Phenotype in Transgenic Mice*♦ TA Shelkovnikova, OM Peters, AV Deykin, N Connor-Robson, ... Journal of biological chemistry 288 (35), 25266-25274, 2013 | 149 | 2013 |
γ-Synucleinopathy: neurodegeneration associated with overexpression of the mouse protein N Ninkina, O Peters, S Millership, H Salem, H Van der Putten, ... Human molecular genetics 18 (10), 1779-1794, 2009 | 141 | 2009 |
Mutant Profilin1 transgenic mice recapitulate cardinal features of motor neuron disease D Fil, A DeLoach, S Yadav, D Alkam, M MacNicol, A Singh, ... Human molecular genetics 26 (4), ddw429, 2017 | 90 | 2017 |
Chronic administration of dimebon ameliorates pathology in Tau P301S transgenic mice OM Peters, N Connor-Robson, VB Sokolov, AY Aksinenko, MS Kukharsky, ... Journal of Alzheimer's disease 33 (4), 1041-1049, 2013 | 78 | 2013 |
The mood stabiliser lithium suppresses PIP3 signalling in Dictyostelium and human cells JS King, R Teo, J Ryves, JV Reddy, O Peters, B Orabi, O Hoeller, ... Disease models & mechanisms 2 (5-6), 306-312, 2009 | 77 | 2009 |
Combinational losses of synucleins reveal their differential requirements for compensating age-dependent alterations in motor behavior and dopamine metabolism N Connor-Robson, OM Peters, S Millership, N Ninkina, VL Buchman Neurobiology of Aging 46, 107-112, 2016 | 60 | 2016 |
Dimebon slows progression of proteinopathy in γ-synuclein transgenic mice SO Bachurin, TA Shelkovnikova, AA Ustyugov, O Peters, I Khritankova, ... Neurotoxicity research 22, 33-42, 2012 | 58 | 2012 |
Loss of Sarm1 does not suppress motor neuron degeneration in the SOD1G93A mouse model of amyotrophic lateral sclerosis OM Peters, EA Lewis, JM Osterloh, A Weiss, JS Salameh, J Metterville, ... Human Molecular Genetics 27 (21), 3761-3771, 2018 | 53 | 2018 |
Contrasting effects of α-synuclein and γ-synuclein on the phenotype of cysteine string protein α (CSPα) null mutant mice suggest distinct function of these proteins in neuronal … N Ninkina, OM Peters, N Connor-Robson, O Lytkina, E Sharfeddin, ... Journal of Biological Chemistry 287 (53), 44471-44477, 2012 | 46 | 2012 |
Selective pattern of motor system damage in gamma-synuclein transgenic mice mirrors the respective pathology in amyotrophic lateral sclerosis OM Peters, S Millership, TA Shelkovnikova, I Soto, L Keeling, A Hann, ... Neurobiology of disease 48 (1), 124-131, 2012 | 42 | 2012 |
Injury-induced inhibition of bystander neurons requires dSarm and signaling from glia JM Hsu, Y Kang, MM Corty, D Mathieson, OM Peters, MR Freeman Neuron 109 (3), 473-487. e5, 2021 | 38 | 2021 |
Gamma‐synuclein pathology in amyotrophic lateral sclerosis OM Peters, T Shelkovnikova, JR Highley, J Cooper‐Knock, T Hortobágyi, ... Annals of Clinical and Translational Neurology 2 (1), 29-37, 2015 | 34 | 2015 |
Chronic administration of Dimebon does not ameliorate amyloid-β pathology in 5xFAD transgenic mice OM Peters, T Shelkovnikova, T Tarasova, S Springe, MS Kukharsky, ... Journal of Alzheimer's Disease 36 (3), 589-596, 2013 | 34 | 2013 |
Proteinopathies, neurodegenerative disorders with protein aggregation-based pathology TA Shelkovnikova, AA Kulikova, PO Tsvetkov, O Peters, SO Bachurin, ... Molecular Biology 46, 362-374, 2012 | 33 | 2012 |
Hindering of proteinopathy-induced neurodegeneration as a new mechanism of action for neuroprotectors and cognition enhancing compounds. SO Bachurin, AA Ustyugov, O Peters, TA Shelkovnikova, VL Buchman, ... Doklady Biochemistry & Biophysics 428 (1), 2009 | 32 | 2009 |