| Recent advances and promises in nitrile hydratase: From mechanism to industrial applications Z Cheng, Y Xia, Z Zhou Frontiers in bioengineering and biotechnology 8, 352, 2020 | 52 | 2020 |
| Identification of key residues modulating the stereoselectivity of nitrile hydratase toward rac‐mandelonitrile by semi‐rational engineering Z Cheng, L Peplowski, W Cui, Y Xia, Z Liu, J Zhang, M Kobayashi, Z Zhou Biotechnology and Bioengineering 115 (3), 524-535, 2018 | 32 | 2018 |
| Computational Design of Nitrile Hydratase from Pseudonocardia thermophila JCM3095 for Improved Thermostability Z Cheng, Y Lan, J Guo, D Ma, S Jiang, Q Lai, Z Zhou, L Peplowski Molecules 25 (20), 4806, 2020 | 29 | 2020 |
| Improving the thermostability and catalytic efficiency of the subunit‐fused nitrile hydratase by semi‐rational engineering Y Xia, W Cui, Z Cheng, L Peplowski, Z Liu, M Kobayashi, Z Zhou ChemCatChem 10 (6), 1370-1375, 2018 | 28 | 2018 |
| Development of a base editor for protein evolution via in situ mutation in vivo W Hao, W Cui, Z Cheng, L Han, F Suo, Z Liu, L Zhou, Z Zhou Nucleic Acids Research 49 (16), 9594-9605, 2021 | 24 | 2021 |
| A switch in a substrate tunnel for directing regioselectivity of nitrile hydratases towards α, ω-dinitriles Z Cheng, W Cui, Z Liu, L Zhou, M Wang, M Kobayashi, Z Zhou Catalysis Science & Technology 6 (5), 1292-1296, 2016 | 22 | 2016 |
| Substrate access tunnel engineering for improving the catalytic activity of a thermophilic nitrile hydratase toward pyridine and pyrazine nitriles Z Cheng, S Jiang, Z Zhou Biochemical and Biophysical Research Communications 575, 8-13, 2021 | 21 | 2021 |
| Insight into the broadened substrate scope of nitrile hydratase by static and dynamic structure analysis D Ma, Z Cheng, L Peplowski, L Han, Y Xia, X Hou, J Guo, D Yin, Y Rao, ... Chemical Science 13 (28), 8417-8428, 2022 | 20 | 2022 |
| Effect and mechanism analysis of different linkers on efficient catalysis of subunit-fused nitrile hydratase J Guo, Z Cheng, J Berdychowska, X Zhu, L Wang, L Peplowski, Z Zhou International Journal of Biological Macromolecules 181, 444-451, 2021 | 20 | 2021 |
| Metallochaperone function of the self‐subunit swapping chaperone involved in the maturation of subunit‐fused cobalt‐type nitrile hydratase Y Xia, L Peplowski, Z Cheng, T Wang, Z Liu, W Cui, M Kobayashi, Z Zhou Biotechnology and Bioengineering 116 (3), 481-489, 2019 | 18 | 2019 |
| Modulation of nitrile hydratase regioselectivity towards dinitriles by tailoring the substrate binding pocket residues Z Cheng, W Cui, Y Xia, L Peplowski, M Kobayashi, Z Zhou ChemCatChem 10 (2), 449-458, 2018 | 18 | 2018 |
| Data-Driven and in Silico-Assisted Design of Broad Host-Range Minimal Intrinsic Terminators Adapted for Bacteria W Cui, Q Lin, R Hu, L Han, Z Cheng, L Zhang, Z Zhou ACS Synthetic Biology 10 (6), 1438-1450, 2021 | 17 | 2021 |
| Modulating the pH profile of the pullulanase from Pyrococcus yayanosii CH1 by synergistically engineering the active center and surface T Xie, L Zhou, L Han, W Cui, Z Liu, Z Cheng, J Guo, Z Zhou International Journal of Biological Macromolecules 216, 132-139, 2022 | 13 | 2022 |
| Construction and application of an efficient dual-base editing platform for Bacillus subtilis evolution employing programmable base conversion W Hao, W Cui, F Suo, L Han, Z Cheng, Z Zhou Chemical Science 13 (48), 14395-14409, 2022 | 13 | 2022 |
| “Toolbox” construction of an extremophilic nitrile hydratase from Streptomyces thermoautotrophicus for the promising industrial production of various amides J Guo, J Berdychowska, Q Lai, Y Meng, Z Cheng, L Peplowski, Z Zhou International Journal of Biological Macromolecules 221, 1103-1111, 2022 | 11 | 2022 |
| Construction and Application of a High-Throughput In Vivo Screening Platform for the Evolution of Nitrile Metabolism-Related Enzymes Based on a Desensitized … L Han, X Liu, Z Cheng, W Cui, J Guo, J Yin, Z Zhou ACS Synthetic Biology 11 (4), 1577-1587, 2022 | 10 | 2022 |
| Enzymatic Biosynthesis of l-2-Aminobutyric Acid by Glutamate Mutase Coupled with l-Aspartate-β-decarboxylase Using l-Glutamate as the Sole Substrate Y Liu, L Han, Z Cheng, Z Liu, Z Zhou ACS Catalysis 10 (23), 13913-13917, 2020 | 10 | 2020 |
| Engineering of the thermophilic nitrile hydratase from Pseudonocardia thermophila JCM3095 for large-scale nicotinamide production based on sequence-activity relationships Z Zhou, D Ma, Z Cheng International Journal of Biological Macromolecules 191, 775-782, 2021 | 9 | 2021 |
| Discovery of the ATPase Activity of a Cobalt-Type Nitrile Hydratase Activator and Its Promoting Effect on Enzyme Maturation Y Xia, Z Cheng, C Hou, L Peplowski, Z Zhou, X Chen Biochemistry 61 (24), 2940-2947, 2022 | 6 | 2022 |
| Efficient Overproduction of Active Nitrile Hydratase by Coupling Expression Induction and Enzyme Maturation via Programming a Controllable Cobalt-Responsive … L Han, W Cui, Q Lin, Q Chen, F Suo, K Ma, Y Wang, W Hao, Z Cheng, ... Frontiers in Bioengineering and Biotechnology 8, 193, 2020 | 6 | 2020 |
