Pan-cancer analysis of whole genomes PCAWG Consortium Nature 578 (7793), 82, 2020 | 1839* | 2020 |
CTCF/cohesin-binding sites are frequently mutated in cancer R Katainen, K Dave, E Pitkänen, K Palin, T Kivioja, N Välimäki, AE Gylfe, ... Nature genetics 47 (7), 818-821, 2015 | 464 | 2015 |
Characterization of uterine leiomyomas by whole-genome sequencing M Mehine, E Kaasinen, N Mäkinen, R Katainen, K Kämpjärvi, E Pitkänen, ... New England Journal of Medicine 369 (1), 43-53, 2013 | 360 | 2013 |
The Glanville fritillary genome retains an ancient karyotype and reveals selective chromosomal fusions in Lepidoptera V Ahola, R Lehtonen, P Somervuo, L Salmela, P Koskinen, P Rastas, ... Nature communications 5 (1), 4737, 2014 | 241 | 2014 |
Integrated data analysis reveals uterine leiomyoma subtypes with distinct driver pathways and biomarkers M Mehine, E Kaasinen, HR Heinonen, N Mäkinen, K Kämpjärvi, ... Proceedings of the National Academy of Sciences 113 (5), 1315-1320, 2016 | 219 | 2016 |
Exome sequencing reveals frequent inactivating mutations in ARID1A, ARID1B, ARID2 and ARID4A in microsatellite unstable colorectal cancer T Cajuso, UA Hänninen, J Kondelin, AE Gylfe, T Tanskanen, R Katainen, ... International journal of cancer 135 (3), 611-623, 2014 | 130 | 2014 |
Comparative Genome-Scale Reconstruction of Gapless Metabolic Networks for Present and Ancestral Species E Pitkänen, P Jouhten, J Hou, MS Fahad, P Blomberg, J Kludas, M Oja, ... PLOS Computational Biology 10 (2), e1003465, 2014 | 109 | 2014 |
Whole-genome sequencing of growth hormone (GH)-secreting pituitary adenomas N Välimäki, H Demir, E Pitkänen, E Kaasinen, A Karppinen, L Kivipelto, ... The Journal of Clinical Endocrinology & Metabolism 100 (10), 3918-3927, 2015 | 98 | 2015 |
Eleven Candidate Susceptibility Genes for Common Familial Colorectal Cancer AE Gylfe, R Katainen, J Kondelin, T Tanskanen, T Cajuso, U Hänninen, ... PLOS Genetics 9 (10), e1003876, 2013 | 98 | 2013 |
Inferring branching pathways in genome-scale metabolic networks E Pitkänen, P Jouhten, J Rousu BMC systems biology 3 (1), 103, 2009 | 91 | 2009 |
MED12 mutation frequency in unselected sporadic uterine leiomyomas HR Heinonen, NS Sarvilinna, J Sjöberg, K Kämpjärvi, E Pitkänen, ... Fertility and sterility 102 (4), 1137-1142, 2014 | 85 | 2014 |
Exome-wide somatic mutation characterization of small bowel adenocarcinoma UA Hänninen, R Katainen, T Tanskanen, RM Plaketti, R Laine, ... PLoS genetics 14 (3), e1007200, 2018 | 80 | 2018 |
Identification of 33 candidate oncogenes by screening for base-specific mutations S Tuupanen, UA Hänninen, J Kondelin, P Von Nandelstadh, T Cajuso, ... British journal of cancer 111 (8), 1657-1662, 2014 | 80 | 2014 |
Identification of candidate oncogenes in human colorectal cancers with microsatellite instability AE Gylfe, J Kondelin, M Turunen, H Ristolainen, R Katainen, E Pitkänen, ... Gastroenterology 145 (3), 540-543. e22, 2013 | 78 | 2013 |
Comparative analysis of molecular fingerprints in prediction of drug combination effects B Zagidullin, Z Wang, Y Guan, E Pitkänen, J Tang Briefings in bioinformatics 22 (6), bbab291, 2021 | 72 | 2021 |
Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival T Cajuso, P Sulo, T Tanskanen, R Katainen, A Taira, UA Hänninen, ... Nature communications 10 (1), 4022, 2019 | 69 | 2019 |
Frequent L1 retrotranspositions originating from TTC28 in colorectal cancer E Pitkänen, T Cajuso, R Katainen, E Kaasinen, N Välimäki, K Palin, ... Oncotarget 5 (3), 853–859, 2014 | 67 | 2014 |
Multiple clinical characteristics separate MED12-mutation-positive and -negative uterine leiomyomas HR Heinonen, A Pasanen, O Heikinheimo, T Tanskanen, K Palin, ... Scientific reports 7 (1), 1015, 2017 | 66 | 2017 |
Molecular features encoded in the ctDNA reveal heterogeneity and predict outcome in high-risk aggressive B-cell lymphoma L Meriranta, A Alkodsi, A Pasanen, M Lepistö, P Mapar, YN Blaker, ... Blood, The Journal of the American Society of Hematology 139 (12), 1863-1877, 2022 | 62 | 2022 |
Towards structured output prediction of enzyme function K Astikainen, L Holm, E Pitkänen, S Szedmak, J Rousu BMC proceedings 2 (Suppl 4), S2, 2008 | 60 | 2008 |