Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans T Hikida, H Jaaro-Peled, S Seshadri, K Oishi, C Hookway, S Kong, D Wu, ... Proceedings of the National Academy of Sciences 104 (36), 14501-14506, 2007 | 524 | 2007 |
Neurodevelopmental mechanisms of schizophrenia: understanding disturbed postnatal brain maturation through neuregulin-1–ErbB4 and DISC1 H Jaaro-Peled, A Hayashi-Takagi, S Seshadri, A Kamiya, NJ Brandon, ... Trends in neurosciences 32 (9), 485-495, 2009 | 390 | 2009 |
Knockdown of DISC1 by in utero gene transfer disturbs postnatal dopaminergic maturation in the frontal cortex and leads to adult behavioral deficits M Niwa, A Kamiya, R Murai, K Kubo, AJ Gruber, K Tomita, L Lu, ... Neuron 65 (4), 480-489, 2010 | 348 | 2010 |
Adolescent stress–induced epigenetic control of dopaminergic neurons via glucocorticoids M Niwa, H Jaaro-Peled, S Tankou, S Seshadri, T Hikida, Y Matsumoto, ... Science 339 (6117), 335-339, 2013 | 346 | 2013 |
Nuclear translocation of mitogen-activated protein kinase kinase (MEK1) in response to mitogenic stimulation H Jaaro, H Rubinfeld, T Hanoch, R Seger Proceedings of the National Academy of Sciences 94 (8), 3742-3747, 1997 | 233 | 1997 |
Review of pathological hallmarks of schizophrenia: comparison of genetic models with patients and nongenetic models H Jaaro-Peled, Y Ayhan, MV Pletnikov, A Sawa Schizophrenia bulletin 36 (2), 301-313, 2010 | 187 | 2010 |
Combined effect of neonatal immune activation and mutant DISC1 on phenotypic changes in adulthood D Ibi, T Nagai, H Koike, Y Kitahara, H Mizoguchi, M Niwa, H Jaaro-Peled, ... Behavioural brain research 206 (1), 32-37, 2010 | 169 | 2010 |
Enhanced dopamine function in DISC1‐L100P mutant mice: implications for schizophrenia TV Lipina, M Niwa, H Jaaro‐Peled, PJ Fletcher, P Seeman, A Sawa, ... Genes, Brain and Behavior 9 (7), 777-789, 2010 | 126 | 2010 |
Cognitive and motivational deficits together with prefrontal oxidative stress in a mouse model for neuropsychiatric illness AW Johnson, H Jaaro-Peled, N Shahani, TW Sedlak, S Zoubovsky, ... Proceedings of the National Academy of Sciences 110 (30), 12462-12467, 2013 | 109 | 2013 |
Rabies virus glycoprotein (RVG) is a trimeric ligand for the N-terminal cysteine-rich domain of the mammalian p75 neurotrophin receptor C Langevin, H Jaaro, S Bressanelli, M Fainzilber, C Tuffereau Journal of Biological Chemistry 277 (40), 37655-37662, 2002 | 104 | 2002 |
Gene models of schizophrenia: DISC1 mouse models H Jaaro-Peled Progress in brain research 179, 75-86, 2009 | 101 | 2009 |
Evolving better brains: a need for neurotrophins? H Jaaro, G Beck, SG Conticello, M Fainzilber TRENDS in Neurosciences 24 (2), 79-85, 2001 | 89 | 2001 |
Neurodevelopmental factors in schizophrenia H Jaaro-Peled, A Sawa Psychiatric Clinics 43 (2), 263-274, 2020 | 82 | 2020 |
CPG16, a novel protein serine/threonine kinase downstream of cAMP-dependent protein kinase MA Silverman, O Benard, H Jaaro, A Rattner, Y Citri, R Seger Journal of Biological Chemistry 274 (5), 2631-2636, 1999 | 73 | 1999 |
Utility and validity of DISC1 mouse models in biological psychiatry T Tomoda, A Sumitomo, H Jaaro-Peled, A Sawa Neuroscience 321, 99-107, 2016 | 71 | 2016 |
Interneuronal DISC1 regulates NRG1-ErbB4 signalling and excitatory–inhibitory synapse formation in the mature cortex S Seshadri, T Faust, K Ishizuka, K Delevich, Y Chung, SH Kim, M Cowles, ... Nature communications 6 (1), 10118, 2015 | 71 | 2015 |
DISC1 a key molecular lead in psychiatry and neurodevelopment: No-More Disrupted-in-Schizophrenia M Niwa, T Cash-Padgett, KI Kubo, A Saito, K Ishii, A Sumitomo, ... Molecular psychiatry 21 (11), 1488, 2016 | 69 | 2016 |
DISC1 regulates trafficking and processing of APP and Aβ generation N Shahani, S Seshadri, H Jaaro-Peled, K Ishizuka, Y Hirota-Tsuyada, ... Molecular psychiatry 20 (7), 874-879, 2015 | 61 | 2015 |
DISC1 mouse models as a tool to decipher gene-environment interactions in psychiatric disorders T Cash-Padgett, H Jaaro-Peled Frontiers in behavioral neuroscience 7, 113, 2013 | 58 | 2013 |
Subcortical dopaminergic deficits in a DISC1 mutant model: a study in direct reference to human molecular brain imaging H Jaaro-Peled, M Niwa, CA Foss, R Murai, S de Los Reyes, A Kamiya, ... Human molecular genetics 22 (8), 1574-1580, 2013 | 52 | 2013 |