Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial P Gautret, JC Lagier, P Parola, L Meddeb, M Mailhe, B Doudier, J Courjon, ... International journal of antimicrobial agents 56 (1), 105949, 2020 | 6624 | 2020 |
Early treatment of COVID-19 patients with hydroxychloroquine and azithromycin: a retrospective analysis of 1061 cases in Marseille, France M Million, JC Lagier, P Gautret, P Colson, PE Fournier, S Amrane, ... Travel medicine and infectious disease 35, 101738, 2020 | 579 | 2020 |
Interference in bacterial quorum sensing: a biopharmaceutical perspective B Rémy, S Mion, L Plener, M Elias, E Chabrière, D Daudé Frontiers in pharmacology 9, 203, 2018 | 338 | 2018 |
Outcomes of 3,737 COVID-19 patients treated with hydroxychloroquine/azithromycin and other regimens in Marseille, France: A retrospective analysis JC Lagier, M Million, P Gautret, P Colson, S Cortaredona, ... Travel medicine and infectious disease 36, 101791, 2020 | 301 | 2020 |
The molecular basis of phosphate discrimination in arsenate-rich environments M Elias, A Wellner, K Goldin-Azulay, E Chabriere, JA Vorholt, TJ Erb, ... Nature 491 (7422), 134-137, 2012 | 238 | 2012 |
Crystal structures of the key anaerobic enzyme pyruvate: ferredoxin oxidoreductase, free and in complex with pyruvate E Chabrière, MH Charon, A Volbeda, L Pieulle, EC Hatchikian, ... Nature structural biology 6 (2), 182-190, 1999 | 232 | 1999 |
Structural basis for natural lactonase and promiscuous phosphotriesterase activities M Elias, J Dupuy, L Merone, L Mandrich, E Porzio, S Moniot, D Rochu, ... Journal of molecular biology 379 (5), 1017-1028, 2008 | 196 | 2008 |
Human paraoxonase: a promising approach for pre-treatment and therapy of organophosphorus poisoning D Rochu, E Chabrière, P Masson Toxicology 233 (1-3), 47-59, 2007 | 191 | 2007 |
Biotechnological applications of quorum quenching enzymes J Bzdrenga, D Daude, B Remy, P Jacquet, L Plener, M Elias, E Chabriere Chemico-biological interactions 267, 104-115, 2017 | 169 | 2017 |
Crystal structure of the free radical intermediate of pyruvate: ferredoxin oxidoreductase E Chabriere, X Vernede, B Guigliarelli, MH Charon, EC Hatchikian, ... Science 294 (5551), 2559-2563, 2001 | 169 | 2001 |
Clostridium butyricum Strains and Dysbiosis Linked to Necrotizing Enterocolitis in Preterm Neonates N Cassir, S Benamar, JB Khalil, O Croce, M Saint-Faust, A Jacquot, ... Clinical Infectious Diseases 61 (7), 1107-1115, 2015 | 153 | 2015 |
Effect of Quorum Quenching Lactonase in Clinical Isolates of Pseudomonas aeruginosa and Comparison with Quorum Sensing Inhibitors A Guendouze, L Plener, J Bzdrenga, P Jacquet, B Rémy, M Elias, ... Frontiers in microbiology 8, 227, 2017 | 149 | 2017 |
Tandem purification of two HDL-associated partner proteins in human plasma, paraoxonase (PON1) and phosphate binding protein (HPBP) using hydroxyapatite chromatography F Renault, E Chabrière, JP Andrieu, B Dublet, P Masson, D Rochu Journal of Chromatography B 836 (1-2), 15-21, 2006 | 134 | 2006 |
MIMIVIRE is a defence system in mimivirus that confers resistance to virophage A Levasseur, M Bekliz, E Chabrière, P Pontarotti, B La Scola, D Raoult Nature 531 (7593), 249-252, 2016 | 118 | 2016 |
Inhaled lactonase reduces Pseudomonas aeruginosa quorum sensing and mortality in rat pneumonia S Hraiech, J Hiblot, J Lafleur, H Lepidi, L Papazian, JM Rolain, D Raoult, ... PLoS One 9 (10), e107125, 2014 | 111 | 2014 |
Characterisation of the organophosphate hydrolase catalytic activity of SsoPox J Hiblot, G Gotthard, E Chabriere, M Elias Scientific reports 2 (1), 779, 2012 | 101 | 2012 |
Oligomeric states of the detergent-solubilized human serum paraoxonase (PON1) D Josse, C Ebel, D Stroebel, A Fontaine, F Borges, A Echalier, D Baud, ... Journal of Biological Chemistry 277 (36), 33386-33397, 2002 | 98 | 2002 |
Current and emerging strategies for organophosphate decontamination: special focus on hyperstable enzymes P Jacquet, D Daudé, J Bzdrenga, P Masson, M Elias, E Chabrière Environmental Science and Pollution Research 23, 8200-8218, 2016 | 97 | 2016 |
Differential Active Site Loop Conformations Mediate Promiscuous Activities in the Lactonase SsoPox J Hiblot, G Gotthard, M Elias, E Chabriere PLoS One 8 (9), e75272, 2013 | 97 | 2013 |
Structural and Enzymatic characterization of the lactonase SisLac from Sulfolobus islandicus J Hiblot, G Gotthard, E Chabriere, M Elias Public Library of Science 7 (10), e47028, 2012 | 93 | 2012 |