Prion-like C-terminal domain of TDP-43 and α-Synuclein interact synergistically to generate neurotoxic hybrid fibrils S Dhakal, CE Wyant, HE George, SE Morgan, V Rangachari Journal of molecular biology 433 (10), 166953, 2021 | 51 | 2021 |
Phytochemical and antioxidant studies of methanol and chloroform extract from leaves of Azadirachta indica A. Juss. in Tropical region of Nepal S Dhakal, P Aryal, S Aryal, D Bashyal, D Khadka Journal of Pharmacognosy and Phytotherapy 8 (12), 203-208, 2016 | 30 | 2016 |
Charge and redox states modulate granulin—TDP-43 coacervation toward phase separation or aggregation AA Bhopatkar, S Dhakal, HG Abernathy, SE Morgan, V Rangachari Biophysical journal 121 (11), 2107-2126, 2022 | 13 | 2022 |
Biophysical characteristics of lipid‐induced Aβ oligomers correlate to distinctive phenotypes in transgenic mice J Saha, DN Dean, S Dhakal, KA Stockmal, SE Morgan, KD Dillon, ... The FASEB Journal 35 (2), 2021 | 12 | 2021 |
Management and outcome of severe Sepsis and septic shock patients S Lamichhane, N Manandhar, S Dhakal, YL Shakya Nepal Health Research Council, 2018 | 12 | 2018 |
Cloning, expression and purification of the low-complexity region of RanBP9 protein S Dhakal, K Sapkota, F Huang, V Rangachari Protein expression and purification 172, 105630, 2020 | 10 | 2020 |
Distinct neurotoxic TDP-43 fibril polymorphs are generated by heterotypic interactions with α-Synuclein S Dhakal, AS Robang, N Bhatt, N Puangmalai, L Fung, R Kayed, ... Journal of Biological Chemistry 298 (11), 2022 | 9 | 2022 |
α-Synuclein emulsifies TDP-43 prion-like domain—RNA liquid droplets to promote heterotypic amyloid fibrils S Dhakal, M Mondal, A Mirzazadeh, S Banerjee, A Ghosh, V Rangachari Communications Biology 6 (1), 1227, 2023 | 8 | 2023 |
Ganglioside-Enriched Phospholipid Vesicles Induce Cooperative Aβ Oligomerization and Membrane Disruption J Saha, P Bose, S Dhakal, P Ghosh, V Rangachari Biochemistry, 2022 | 8 | 2022 |
αS oligomers generated from interactions with a polyunsaturated fatty acid and a dopamine metabolite differentially interact with Aβ to enhance neurotoxicity S Dhakal, J Saha, CE Wyant, V Rangachari ACS chemical neuroscience 12 (21), 4153-4161, 2021 | 8 | 2021 |
Effects of vesicular membrane composition on amyloid-beta oligomerization J Saha, P Bose, S Dhakal, P Ghosh, V Rangachari Biophysical Journal 121 (3), 56a, 2022 | | 2022 |
Granulins modulate liquid-liquid phase separation or aggregation of prion-like domain of TDP-43 by electrostatic interactions and the redox state of cysteines A Bhopatkar, S Dhakal, V Rangachari Biophysical Journal 121 (3), 474a, 2022 | | 2022 |
Synergistic interactions between α-synuclein and prion-like C-terminal domain of TDP-43 S Dhakal, V Rangachari Biophysical Journal 121 (3), 55a, 2022 | | 2022 |
αS oligomers generated from polyunsaturated fatty acid and dopamine metabolite differentially interact with Aβ to enhance neurotoxicity S Dhakal, J Saha, CE Wyant, V Rangachari bioRxiv, 2021.08. 08.455587, 2021 | | 2021 |
Cytoplasmic Colocalization of Granulins and TDP-43 Prion-like Domain Involves Electrostatically Driven Coacervation Tuned by the Redox State of Cysteines AA Bhopatkar, S Dhakal, V Rangachari bioRxiv, 2021.06. 25.449959, 2021 | | 2021 |
PHYTOCHEMICAL SCREENING AND COMPARISON OF ANTIOXIDANT AND ANTI-INFLAMMATORY POTENTIAL OF AZADIRACHTA INDICA AND JUSTICIA ADHATODA S Dhakal Department of Pharmacy Universal College of Medical Sciences, Tribhuvan …, 2016 | | 2016 |