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Shailendra Dhakal
Shailendra Dhakal
Postdoctoral research fellow, Harvard Medical School
在 mgh.harvard.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Prion-like C-terminal domain of TDP-43 and α-Synuclein interact synergistically to generate neurotoxic hybrid fibrils
S Dhakal, CE Wyant, HE George, SE Morgan, V Rangachari
Journal of molecular biology 433 (10), 166953, 2021
512021
Phytochemical and antioxidant studies of methanol and chloroform extract from leaves of Azadirachta indica A. Juss. in Tropical region of Nepal
S Dhakal, P Aryal, S Aryal, D Bashyal, D Khadka
Journal of Pharmacognosy and Phytotherapy 8 (12), 203-208, 2016
302016
Charge and redox states modulate granulin—TDP-43 coacervation toward phase separation or aggregation
AA Bhopatkar, S Dhakal, HG Abernathy, SE Morgan, V Rangachari
Biophysical journal 121 (11), 2107-2126, 2022
132022
Biophysical characteristics of lipid‐induced Aβ oligomers correlate to distinctive phenotypes in transgenic mice
J Saha, DN Dean, S Dhakal, KA Stockmal, SE Morgan, KD Dillon, ...
The FASEB Journal 35 (2), 2021
122021
Management and outcome of severe Sepsis and septic shock patients
S Lamichhane, N Manandhar, S Dhakal, YL Shakya
Nepal Health Research Council, 2018
122018
Cloning, expression and purification of the low-complexity region of RanBP9 protein
S Dhakal, K Sapkota, F Huang, V Rangachari
Protein expression and purification 172, 105630, 2020
102020
Distinct neurotoxic TDP-43 fibril polymorphs are generated by heterotypic interactions with α-Synuclein
S Dhakal, AS Robang, N Bhatt, N Puangmalai, L Fung, R Kayed, ...
Journal of Biological Chemistry 298 (11), 2022
92022
α-Synuclein emulsifies TDP-43 prion-like domain—RNA liquid droplets to promote heterotypic amyloid fibrils
S Dhakal, M Mondal, A Mirzazadeh, S Banerjee, A Ghosh, V Rangachari
Communications Biology 6 (1), 1227, 2023
82023
Ganglioside-Enriched Phospholipid Vesicles Induce Cooperative Aβ Oligomerization and Membrane Disruption
J Saha, P Bose, S Dhakal, P Ghosh, V Rangachari
Biochemistry, 2022
82022
αS oligomers generated from interactions with a polyunsaturated fatty acid and a dopamine metabolite differentially interact with Aβ to enhance neurotoxicity
S Dhakal, J Saha, CE Wyant, V Rangachari
ACS chemical neuroscience 12 (21), 4153-4161, 2021
82021
Effects of vesicular membrane composition on amyloid-beta oligomerization
J Saha, P Bose, S Dhakal, P Ghosh, V Rangachari
Biophysical Journal 121 (3), 56a, 2022
2022
Granulins modulate liquid-liquid phase separation or aggregation of prion-like domain of TDP-43 by electrostatic interactions and the redox state of cysteines
A Bhopatkar, S Dhakal, V Rangachari
Biophysical Journal 121 (3), 474a, 2022
2022
Synergistic interactions between α-synuclein and prion-like C-terminal domain of TDP-43
S Dhakal, V Rangachari
Biophysical Journal 121 (3), 55a, 2022
2022
αS oligomers generated from polyunsaturated fatty acid and dopamine metabolite differentially interact with Aβ to enhance neurotoxicity
S Dhakal, J Saha, CE Wyant, V Rangachari
bioRxiv, 2021.08. 08.455587, 2021
2021
Cytoplasmic Colocalization of Granulins and TDP-43 Prion-like Domain Involves Electrostatically Driven Coacervation Tuned by the Redox State of Cysteines
AA Bhopatkar, S Dhakal, V Rangachari
bioRxiv, 2021.06. 25.449959, 2021
2021
PHYTOCHEMICAL SCREENING AND COMPARISON OF ANTIOXIDANT AND ANTI-INFLAMMATORY POTENTIAL OF AZADIRACHTA INDICA AND JUSTICIA ADHATODA
S Dhakal
Department of Pharmacy Universal College of Medical Sciences, Tribhuvan …, 2016
2016
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