| Atomic-resolution protein structure determination by cryo-EM KM Yip, N Fischer, E Paknia, A Chari, H Stark Nature 587 (7832), 157-161, 2020 | 696 | 2020 |
| Cryo-EM in drug discovery: achievements, limitations and prospects JP Renaud, A Chari, C Ciferri, W Liu, HW Rémigy, H Stark, C Wiesmann Nature reviews Drug discovery 17 (7), 471-492, 2018 | 449 | 2018 |
| X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease S Günther, PYA Reinke, Y Fernández-García, J Lieske, TJ Lane, HM Ginn, ... Science 372 (6542), 642-646, 2021 | 330 | 2021 |
| An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs A Chari, MM Golas, M Klingenhäger, N Neuenkirchen, B Sander, ... Cell 135 (3), 497-509, 2008 | 259 | 2008 |
| The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design J Schrader, F Henneberg, RA Mata, K Tittmann, TR Schneider, H Stark, ... Science 353 (6299), 594-598, 2016 | 234 | 2016 |
| Molecular architecture of the Saccharomyces cerevisiae activated spliceosome R Rauhut, P Fabrizio, O Dybkov, K Hartmuth, V Pena, A Chari, V Kumar, ... Science 353 (6306), 1399-1405, 2016 | 186 | 2016 |
| A comprehensive interaction map of the human survival of motor neuron (SMN) complex S Otter, M Grimmler, N Neuenkirchen, A Chari, A Sickmann, U Fischer Journal of Biological Chemistry 282 (8), 5825-5833, 2007 | 176 | 2007 |
| Translation and replication of hepatitis C virus genomic RNA depends on ancient cellular proteins that control mRNA fates N Scheller, LB Mina, RP Galão, A Chari, M Giménez-Barcons, A Noueiry, ... Proceedings of the National Academy of Sciences 106 (32), 13517-13522, 2009 | 172 | 2009 |
| Biogenesis of spliceosomal small nuclear ribonucleoproteins U Fischer, C Englbrecht, A Chari Wiley Interdisciplinary Reviews: RNA 2 (5), 718-731, 2011 | 161 | 2011 |
| Spinal muscular atrophy: the RNP connection C Eggert, A Chari, B Laggerbauer, U Fischer Trends in molecular medicine 12 (3), 113-121, 2006 | 154 | 2006 |
| Deciphering the assembly pathway of Sm-class U snRNPs N Neuenkirchen, A Chari, U Fischer FEBS letters 582 (14), 1997-2003, 2008 | 133 | 2008 |
| IGHMBP2 is a ribosome-associated helicase inactive in the neuromuscular disorder distal SMA type 1 (DSMA1) UP Guenther, L Handoko, B Laggerbauer, S Jablonka, A Chari, ... Human molecular genetics 18 (7), 1288-1300, 2009 | 130 | 2009 |
| Evolution of an RNP assembly system: a minimal SMN complex facilitates formation of UsnRNPs in Drosophila melanogaster M Kroiss, J Schultz, J Wiesner, A Chari, A Sickmann, U Fischer Proceedings of the National Academy of Sciences 105 (29), 10045-10050, 2008 | 119 | 2008 |
| ProteoPlex: stability optimization of macromolecular complexes by sparse-matrix screening of chemical space A Chari, D Haselbach, JM Kirves, J Ohmer, E Paknia, N Fischer, ... Nature methods 12 (9), 859-865, 2015 | 116 | 2015 |
| Structural basis of assembly chaperone-mediated snRNP formation C Grimm, A Chari, JP Pelz, J Kuper, C Kisker, K Diederichs, H Stark, ... Molecular cell 49 (4), 692-703, 2013 | 112 | 2013 |
| The role of RNP biogenesis in spinal muscular atrophy A Chari, E Paknia, U Fischer Current opinion in cell biology 21 (3), 387-393, 2009 | 99 | 2009 |
| Unrip, a factor implicated in cap-independent translation, associates with the cytosolic SMN complex and influences its intracellular localization M Grimmler, S Otter, C Peter, F Müller, A Chari, U Fischer Human molecular genetics 14 (20), 3099-3111, 2005 | 99 | 2005 |
| Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs D Haselbach, J Schrader, F Lambrecht, F Henneberg, A Chari, H Stark Nature communications 8 (1), 15578, 2017 | 67 | 2017 |
| Reconstitution of the human U sn RNP assembly machinery reveals stepwise Sm protein organization N Neuenkirchen, C Englbrecht, J Ohmer, T Ziegenhals, A Chari, U Fischer The EMBO journal 34 (14), 1925-1941, 2015 | 61 | 2015 |
| Proteasomal degradation of the intrinsically disordered protein tau at single-residue resolution T Ukmar-Godec, P Fang, A Ibáñez de Opakua, F Henneberg, A Godec, ... Science advances 6 (30), eaba3916, 2020 | 55 | 2020 |
