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Ake Tzu-Hui Lu
Ake Tzu-Hui Lu
Senior Scientist, Computational, San Diego Institute of Science, Altos Labs
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An epigenetic biomarker of aging for lifespan and healthspan
ME Levine, AT Lu, A Quach, BH Chen, TL Assimes, S Bandinelli, L Hou, ...
Aging (albany NY) 10 (4), 573, 2018
20642018
DNA methylation GrimAge strongly predicts lifespan and healthspan
AT Lu, A Quach, JG Wilson, AP Reiner, A Aviv, K Raj, L Hou, ...
Aging (albany NY) 11 (2), 303, 2019
14622019
DNA methylation-based measures of biological age: meta-analysis predicting time to death
BH Chen, RE Marioni, E Colicino, MJ Peters, CK Ward-Caviness, PC Tsai, ...
Aging (Albany NY) 8 (9), 1844, 2016
9962016
Detection of macular ganglion cell loss in glaucoma by Fourier-domain optical coherence tomography
O Tan, V Chopra, ATH Lu, JS Schuman, H Ishikawa, G Wollstein, ...
Ophthalmology 116 (12), 2305-2314. e2, 2009
8602009
An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease
S Horvath, M Gurven, ME Levine, BC Trumble, H Kaplan, H Allayee, ...
Genome biology 17, 1-23, 2016
6802016
Epigenetic clock analysis of diet, exercise, education, and lifestyle factors
A Quach, ME Levine, T Tanaka, AT Lu, BH Chen, L Ferrucci, B Ritz, ...
Aging (albany NY) 9 (2), 419, 2017
6622017
Mapping of macular substructures with optical coherence tomography for glaucoma diagnosis
O Tan, G Li, ATH Lu, R Varma, D Huang, ...
Ophthalmology 115 (6), 949-956, 2008
5152008
Epigenetic clock for skin and blood cells applied to Hutchinson Gilford Progeria Syndrome and ex vivo studies
S Horvath, J Oshima, GM Martin, AT Lu, A Quach, H Cohen, S Felton, ...
Aging (Albany NY) 10 (7), 1758, 2018
5012018
Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer’s disease related cognitive functioning
ME Levine, AT Lu, DA Bennett, S Horvath
Aging (Albany NY) 7 (12), 1198, 2015
4502015
Menopause accelerates biological aging
ME Levine, AT Lu, BH Chen, DG Hernandez, AB Singleton, L Ferrucci, ...
Proceedings of the National Academy of Sciences 113 (33), 9327-9332, 2016
4402016
Keratoconus diagnosis with optical coherence tomography pachymetry mapping
Y Li, DM Meisler, M Tang, ATH Lu, V Thakrar, BJ Reiser, D Huang
Ophthalmology 115 (12), 2159-2166, 2008
3002008
GrimAge outperforms other epigenetic clocks in the prediction of age-related clinical phenotypes and all-cause mortality
C McCrory, G Fiorito, B Hernandez, S Polidoro, AM O’Halloran, A Hever, ...
The Journals of Gerontology: Series A 76 (5), 741-749, 2021
2772021
DNA methylation-based estimator of telomere length
AT Lu, A Seeboth, PC Tsai, D Sun, A Quach, AP Reiner, C Kooperberg, ...
Aging (Albany NY) 11 (16), 5895, 2019
2592019
The cerebellum ages slowly according to the epigenetic clock
S Horvath, V Mah, AT Lu, JS Woo, OW Choi, AJ Jasinska, JA Riancho, ...
Aging (Albany NY) 7 (5), 294, 2015
2102015
A quantitative trait locus analysis of social responsiveness in multiplex autism families
JA Duvall, A Lu, RM Cantor, RD Todd, JN Constantino, DH Geschwind
American Journal of Psychiatry 164 (4), 656-662, 2007
1692007
GWAS of epigenetic aging rates in blood reveals a critical role for TERT
AT Lu, L Xue, EL Salfati, BH Chen, L Ferrucci, D Levy, R Joehanes, ...
Nature communications 9 (1), 387, 2018
1672018
A mammalian methylation array for profiling methylation levels at conserved sequences
A Arneson, A Haghani, MJ Thompson, M Pellegrini, SB Kwon, H Vu, ...
Nature communications 13 (1), 783, 2022
1542022
Measurement of total blood flow in the normal human retina using Doppler Fourier-domain optical coherence tomography
Y Wang, A Lu, J Gil-Flamer, O Tan, JA Izatt, D Huang
British Journal of Ophthalmology 93 (5), 634-637, 2009
1512009
Association of the cannabinoid receptor gene (CNR1) with ADHD and post‐traumatic stress disorder
AT Lu, MN Ogdie, MR Järvelin, IK Moilanen, SK Loo, JT McCracken, ...
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 147 …, 2008
1482008
Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging
DL McCartney, JL Min, RC Richmond, AT Lu, MK Sobczyk, G Davies, ...
Genome biology 22, 1-25, 2021
1302021
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