Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing J Ishihara, A Ishihara, K Fukunaga, K Sasaki, MJV White, PS Briquez, ... Nature communications 9 (1), 2163, 2018 | 203 | 2018 |
Collagen-binding IL-12 enhances tumour inflammation and drives the complete remission of established immunologically cold mouse tumours A Mansurov, J Ishihara, P Hosseinchi, L Potin, TM Marchell, A Ishihara, ... Nature biomedical engineering 4 (5), 531-543, 2020 | 174 | 2020 |
Targeted antibody and cytokine cancer immunotherapies through collagen affinity J Ishihara, A Ishihara, K Sasaki, SSY Lee, JM Williford, M Yasui, H Abe, ... Science translational medicine 11 (487), eaau3259, 2019 | 166 | 2019 |
Matrix-binding checkpoint immunotherapies enhance antitumor efficacy and reduce adverse events J Ishihara, K Fukunaga, A Ishihara, HM Larsson, L Potin, P Hosseinchi, ... Science translational medicine 9 (415), eaan0401, 2017 | 160 | 2017 |
Recruitment of CD103+ dendritic cells via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy JM Williford, J Ishihara, A Ishihara, A Mansurov, P Hosseinchi, ... Science advances 5 (12), eaay1357, 2019 | 114 | 2019 |
The heparin binding domain of von Willebrand factor binds to growth factors and promotes angiogenesis in wound healing J Ishihara, A Ishihara, RD Starke, CR Peghaire, KE Smith, TAJ McKinnon, ... Blood, The Journal of the American Society of Hematology 133 (24), 2559-2569, 2019 | 112 | 2019 |
Engineered collagen-binding serum albumin as a drug conjugate carrier for cancer therapy K Sasaki, J Ishihara, A Ishihara, R Miura, A Mansurov, K Fukunaga, ... Science advances 5 (8), eaaw6081, 2019 | 77 | 2019 |
Targeting inflammatory sites through collagen affinity enhances the therapeutic efficacy of anti-inflammatory antibodies K Katsumata, J Ishihara, A Mansurov, A Ishihara, MM Raczy, E Yuba, ... Science advances 5 (11), eaay1971, 2019 | 59 | 2019 |
Improving efficacy and safety of agonistic anti-CD40 antibody through extracellular matrix affinity J Ishihara, A Ishihara, L Potin, P Hosseinchi, K Fukunaga, M Damo, ... Molecular cancer therapeutics 17 (11), 2399-2411, 2018 | 41 | 2018 |
Prolonged residence of an albumin–IL-4 fusion protein in secondary lymphoid organs ameliorates experimental autoimmune encephalomyelitis A Ishihara, J Ishihara, EA Watkins, AC Tremain, M Nguyen, A Solanki, ... Nature Biomedical Engineering 5 (5), 387-398, 2021 | 34 | 2021 |
Suppression of rheumatoid arthritis by enhanced lymph node trafficking of engineered interleukin‐10 in murine models E Yuba, E Budina, K Katsumata, A Ishihara, A Mansurov, AT Alpar, ... Arthritis & Rheumatology 73 (5), 769-778, 2021 | 25 | 2021 |
Conferring extracellular matrix affinity enhances local therapeutic efficacy of anti-TNF-α antibody in a murine model of rheumatoid arthritis K Katsumata, J Ishihara, K Fukunaga, A Ishihara, E Yuba, E Budina, ... Arthritis research & therapy 21, 1-10, 2019 | 17 | 2019 |
Topically-applied collagen-binding serum albumin-fused interleukin-4 modulates wound microenvironment in non-healing wounds AL Lauterbach, RP Wallace, AT Alpar, KC Refvik, JW Reda, A Ishihara, ... NPJ Regenerative Medicine 8 (1), 49, 2023 | 2 | 2023 |
Prolonged residence of an albumin-IL-4 fusion protein in secondary lymphoid organs ameliorates experimental autoimmune encephalomyelitis (Oct, 10.1038/s41551-020-00627-3, 2020) A Ishihara, J Ishihara, EA Watkins, AC Tremain, M Nguyen, A Solanki, ... NATURE BIOMEDICAL ENGINEERING 4 (11), 1117-1117, 2020 | 2 | 2020 |
Methods and compositions for treating inflammatory and autoimmune conditions with ecm-affinity peptides linked to anti-inflammatory agents JA Hubbell, K Katsumata, A Ishihara, J Ishihara, A Mansurov | 1 | 2020 |
Improving Efficacy and Safety of Agonistic Anti-CD40 Antibody Through J Ishihara, A Ishihara, L Potin, P Hosseinchi, K Fukunaga, M Damo, ... | 1 | 2018 |
Methods and compositions for the treatment of wounds JA Hubbell, AM Randi, J Ishihara, A Ishihara, P Briquez, R Starke US Patent App. 18/352,101, 2024 | | 2024 |
Anti-inflammatory cytokines and methods of use JA Hubbell, Y Eiji, E Watkins, J Ishihara, A Ishihara, E Budina, ... US Patent App. 18/246,512, 2024 | | 2024 |
Methods and compositions for the treatment of wounds JA Hubbell, AM Randi, J Ishihara, A Ishihara, P Briquez, R Starke US Patent 11,732,029, 2023 | | 2023 |
Methods of treating cancer with placenta growth factor peptide linked to immunotherapeutic antibodies JA Hubbell, J Ishihara, A Ishihara, K Fukunaga, M Swartz US Patent 11,574,747, 2023 | | 2023 |