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Bhupesh Goyal
Bhupesh Goyal
School of Chemistry & Biochemistry, Thapar Institute of Engineering & Technology, Patiala, India
在 iitbombay.org 的电子邮件经过验证
标题
引用次数
引用次数
年份
Targeting the dimerization of the main protease of coronaviruses: a potential broad-spectrum therapeutic strategy
B Goyal, D Goyal
ACS combinatorial science 22 (6), 297-305, 2020
2812020
Rationally designed peptides and peptidomimetics as inhibitors of amyloid-β (Aβ) aggregation: Potential therapeutics of Alzheimer’s disease
D Goyal, S Shuaib, S Mann, B Goyal
ACS combinatorial science 19 (2), 55-80, 2017
2002017
Benzofuran and indole: promising scaffolds for drug development in Alzheimer's disease
D Goyal, A Kaur, B Goyal
ChemMedChem 13 (13), 1275-1299, 2018
1402018
Multi-target-directed triazole derivatives as promising agents for the treatment of Alzheimer’s disease
A Kaur, S Mann, A Kaur, N Priyadarshi, B Goyal, NK Singhal, D Goyal
Bioorganic chemistry 87, 572-584, 2019
512019
Insights into the inhibitory mechanism of a resveratrol and clioquinol hybrid against Aβ42 aggregation and protofibril destabilization: A molecular dynamics simulation study
RK Saini, S Shuaib, D Goyal, B Goyal
Journal of Biomolecular Structure and Dynamics, 2018
382018
Scrutiny of the mechanism of small molecule inhibitor preventing conformational transition of amyloid-β42 monomer: insights from molecular dynamics simulations
S Shuaib, B Goyal
Journal of Biomolecular Structure and Dynamics 36 (3), 663-678, 2018
362018
Molecular insights into Aβ42 protofibril destabilization with a fluorinated compound D744: A molecular dynamics simulation study
RK Saini, S Shuaib, B Goyal
Journal of Molecular Recognition 30 (12), e2656, 2017
312017
Interactions of a multifunctional di-triazole derivative with Alzheimer's Aβ 42 monomer and Aβ 42 protofibril: a systematic molecular dynamics study
A Kaur, S Shuaib, D Goyal, B Goyal
Physical Chemistry Chemical Physics 22 (3), 1543-1556, 2020
272020
Insights into the Inhibitory Mechanism of Dicyanovinyl‐Substituted J147 Derivative against Aβ42 Aggregation and Protofibril Destabilization: A Molecular Dynamics …
S Shuaib, RK Saini, D Goyal, B Goyal
ChemistrySelect 2 (4), 1645-1657, 2017
272017
Stereochemistry and solvent role in protein folding: nuclear magnetic resonance and molecular dynamics studies of poly-L and alternating-L, D homopolypeptides in dimethyl sulfoxide
KR Srivastava, A Kumar, B Goyal, S Durani
The Journal of Physical Chemistry B 115 (20), 6700-6708, 2011
272011
Multifunctional Mono-Triazole Derivatives Inhibit Aβ42 Aggregation and Cu2+-Mediated Aβ42 Aggregation and Protect Against Aβ42-Induced Cytotoxicity
A Kaur, SS Narang, A Kaur, S Mann, N Priyadarshi, B Goyal, NK Singhal, ...
Chemical Research in Toxicology 32 (9), 1824-1839, 2019
232019
Inhibition of Alzheimer’s amyloid-β42 peptide aggregation by a bi-functional bis-tryptoline triazole: key insights from molecular dynamics simulations
SS Narang, D Goyal, B Goyal
Journal of Biomolecular Structure and Dynamics, 2019
212019
Assessing the effect of D59P mutation in the DE loop region in amyloid aggregation propensity of β2‐microglobulin: A molecular dynamics simulation study
SS Narang, S Shuaib, D Goyal, B Goyal
Journal of cellular biochemistry 119 (1), 782-792, 2018
212018
Targeting human islet amyloid polypeptide aggregation and toxicity in type 2 diabetes: An overview of peptide-based inhibitors
RK Saini, D Goyal, B Goyal
Chemical Research in Toxicology 33 (11), 2719-2738, 2020
202020
CuO nanostructures of variable shapes as an efficient catalyst for [3+ 2] cycloaddition of azides with terminal alkyne
A Kaur, S Mann, B Goyal, B Pal, D Goyal
RSC advances 6 (104), 102733-102743, 2016
192016
A simple synthesis of densely substituted benzofurans by domino reaction of 2-hydroxybenzyl alcohols with 2-substituted furans
AS Makarov, AE Kekhvaeva, PN Chalikidi, VT Abaev, IV Trushkov, ...
Synthesis 51 (19), 3747-3757, 2019
182019
Computational design and evaluation of β‐sheet breaker peptides for destabilizing Alzheimer's amyloid‐β42 protofibrils
S Shuaib, SS Narang, D Goyal, B Goyal
Journal of Cellular Biochemistry 120 (10), 17935-17950, 2019
182019
Molecular insights into the inhibitory mechanism of rifamycin SV against β2–microglobulin aggregation: A molecular dynamics simulation study
SS Narang, S Shuaib, B Goyal
International journal of biological macromolecules 102, 1025-1034, 2017
182017
Impact of K16A and K28A mutation on the structure and dynamics of amyloid-β42 peptide in Alzheimer’s disease: key insights from molecular dynamics simulations
S Shuaib, RK Saini, D Goyal, B Goyal
Journal of Biomolecular Structure and Dynamics, 2019
172019
De novo design of stereochemically-bent sixteen-residue β-hairpin as a hydrolase mimic
B Goyal, K Patel, KR Srivastava, S Durani
RSC advances 5 (127), 105400-105408, 2015
162015
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