A single-cell and spatially resolved atlas of human breast cancers SZ Wu, G Al-Eryani, DL Roden, S Junankar, K Harvey, A Andersson, ... Nature genetics 53 (9), 1334-1347, 2021 | 685 | 2021 |
Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer AS Cazet, MN Hui, BL Elsworth, SZ Wu, D Roden, CL Chan, JN Skhinas, ... Nature communications 9 (1), 1-18, 2018 | 371 | 2018 |
Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease K Mulder, AA Patel, WT Kong, C Piot, E Halitzki, G Dunsmore, ... Immunity 54 (8), 1883-1900. e5, 2021 | 311 | 2021 |
Stromal cell diversity associated with immune evasion in human triple‐negative breast cancer SZ Wu, DL Roden, C Wang, H Holliday, K Harvey, AS Cazet, KJ Murphy, ... The EMBO Journal 39 (19), e104063, 2020 | 275 | 2020 |
High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes M Singh, G Al-Eryani, S Carswell, JM Ferguson, J Blackburn, K Barton, ... Nature communications 10 (1), 1-13, 2019 | 275 | 2019 |
CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan C Vennin, P Mélénec, R Rouet, M Nobis, AS Cazet, KJ Murphy, ... Nature communications 10 (1), 1-22, 2019 | 208 | 2019 |
Spatial deconvolution of HER2-positive breast cancer delineates tumor-associated cell type interactions A Andersson, L Larsson, L Stenbeck, F Salmén, A Ehinger, SZ Wu, ... Nature Communications 12 (1), 1-14, 2021 | 175 | 2021 |
The androgen receptor is a tumor suppressor in estrogen receptor–positive breast cancer TE Hickey, LA Selth, KM Chia, G Laven-Law, HH Milioli, D Roden, ... Nature Medicine 27 (2), 310-320, 2021 | 171 | 2021 |
A niche-dependent myeloid transcriptome signature defines dormant myeloma cells WH Khoo, G Ledergor, A Weiner, DL Roden, RL Terry, MM McDonald, ... Blood 134 (1), 30-43, 2019 | 116 | 2019 |
c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer R Nair, DL Roden, WS Teo, A McFarland, S Junankar, S Ye, A Nguyen, ... Oncogene 33 (30), 3992-4002, 2014 | 114 | 2014 |
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer M Kalyuga, D Gallego-Ortega, HJ Lee, DL Roden, MJ Cowley, CE Caldon, ... PLoS Biol 10 (12), e1001461, 2012 | 103 | 2012 |
ELF5 drives lung metastasis in luminal breast cancer through recruitment of Gr1+ CD11b+ myeloid-derived suppressor cells D Gallego-Ortega, A Ledger, DL Roden, AMK Law, A Magenau, ... PLoS biology 13 (12), e1002330, 2015 | 79 | 2015 |
Prostate cancer cell‐intrinsic interferon signaling regulates dormancy and metastatic outgrowth in bone KL Owen, LJ Gearing, DJ Zanker, NK Brockwell, WH Khoo, DL Roden, ... EMBO reports 21 (6), e50162, 2020 | 68 | 2020 |
ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype S Junankar, LA Baker, DL Roden, R Nair, B Elsworth, D Gallego-Ortega, ... Nature communications 6 (1), 1-12, 2015 | 62 | 2015 |
Single-cell transcriptomics reveals involution mimicry during the specification of the basal breast cancer subtype F Valdes-Mora, R Salomon, BS Gloss, AMK Law, J Venhuizen, L Castillo, ... Cell Reports 35 (2), 108945, 2021 | 55 | 2021 |
MicroRNA profiling of the pubertal mouse mammary gland identifies miR-184 as a candidate breast tumour suppressor gene YW Phua, A Nguyen, DL Roden, B Elsworth, N Deng, I Nikolic, J Yang, ... Breast Cancer Research 17 (1), 1-18, 2015 | 51 | 2015 |
ELF5 isoform expression is tissue-specific and significantly altered in cancer CL Piggin, DL Roden, D Gallego-Ortega, HJ Lee, SR Oakes, CJ Ormandy Breast Cancer Research 18 (1), 1-18, 2016 | 45 | 2016 |
Cryopreservation of human cancers conserves tumour heterogeneity for single-cell multi-omics analysis SZ Wu, DL Roden, G Al-Eryani, N Bartonicek, K Harvey, AS Cazet, ... Genome medicine 13 (1), 1-17, 2021 | 39 | 2021 |
Id proteins promote a cancer stem cell phenotype in mouse models of triple negative breast cancer via negative regulation of robo1 WS Teo, H Holliday, N Karthikeyan, AS Cazet, DL Roden, K Harvey, ... Frontiers in cell and developmental biology, 552, 2020 | 21 | 2020 |
ELF5 modulates the estrogen receptor cistrome in breast cancer CL Piggin, DL Roden, AMK Law, MP Molloy, C Krisp, A Swarbrick, ... PLoS genetics 16 (1), e1008531, 2020 | 20 | 2020 |