Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner VP Chauhan, T Stylianopoulos, JD Martin, Z Popović, O Chen, ... Nature nanotechnology 7 (6), 383-388, 2012 | 1135* | 2012 |
Multistage nanoparticle delivery system for deep penetration into tumor tissue C Wong, T Stylianopoulos, J Cui, J Martin, VP Chauhan, W Jiang, ... Proceedings of the National Academy of Sciences 108 (6), 2426-2431, 2011 | 1113 | 2011 |
The role of mechanical forces in tumor growth and therapy RK Jain, JD Martin, T Stylianopoulos Annual review of biomedical engineering 16, 321-346, 2014 | 996 | 2014 |
Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy Y Huang, J Yuan, E Righi, WS Kamoun, M Ancukiewicz, J Nezivar, ... Proceedings of the National Academy of Sciences 109 (43), 17561-17566, 2012 | 958 | 2012 |
Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels VP Chauhan, JD Martin, H Liu, DA Lacorre, SR Jain, SV Kozin, ... Nature communications 4, 2516, 2013 | 918 | 2013 |
Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors T Stylianopoulos, JD Martin, VP Chauhan, SR Jain, B Diop-Frimpong, ... Proceedings of the National Academy of Sciences 109 (38), 15101-15108, 2012 | 838 | 2012 |
Improving cancer immunotherapy using nanomedicines: progress, opportunities and challenges JD Martin, H Cabral, T Stylianopoulos, RK Jain Nature Reviews Clinical Oncology 17 (4), 251-266, 2020 | 479 | 2020 |
Coevolution of solid stress and interstitial fluid pressure in tumors during progression: Implications for vascular collapse T Stylianopoulos, JD Martin, M Snuderl, F Mpekris, SR Jain, RK Jain Cancer research 73 (13), 3833-3841, 2013 | 446 | 2013 |
Obesity-induced inflammation and desmoplasia promote pancreatic cancer progression and resistance to chemotherapy J Incio, H Liu, P Suboj, SM Chin, IX Chen, M Pinter, MR Ng, HT Nia, ... Cancer discovery 6 (8), 852-869, 2016 | 376 | 2016 |
Normalizing Function of Tumor Vessels: Progress, Opportunities, and Challenges JD Martin, G Seano, RK Jain Annual review of physiology 81, 505-534, 2019 | 367 | 2019 |
Solid stress and elastic energy as measures of tumour mechanopathology HT Nia, H Liu, G Seano, M Datta, D Jones, N Rahbari, J Incio, ... Nature Biomedical Engineering 1, 0004, 2016 | 367 | 2016 |
Modeling the onset of symptoms of COVID-19 JR Larsen, MR Martin, JD Martin, P Kuhn, JB Hicks Frontiers in public health, 473, 2020 | 265 | 2020 |
Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma M Snuderl, A Batista, ND Kirkpatrick, CR de Almodovar, L Riedemann, ... Cell 152 (5), 1065-1076, 2013 | 255 | 2013 |
Role of vascular density and normalization in response to neoadjuvant bevacizumab and chemotherapy in breast cancer patients SM Tolaney, Y Boucher, DG Duda, JD Martin, G Seano, M Ancukiewicz, ... Proceedings of the National Academy of Sciences 112 (46), 14325-14330, 2015 | 238 | 2015 |
Anti-VEGF therapy induces ECM remodeling and mechanical barriers to therapy in colorectal cancer liver metastases NN Rahbari, D Kedrin, J Incio, H Liu, WW Ho, HT Nia, CM Edrich, K Jung, ... Science Translational Medicine 8 (360), 360ra135-360ra135, 2016 | 220 | 2016 |
Anti-vascular endothelial growth factor treatment normalizes tuberculosis granuloma vasculature and improves small molecule delivery M Datta, LE Via, WS Kamoun, C Liu, W Chen, G Seano, DM Weiner, ... Proceedings of the National Academy of Sciences 112 (6), 1827-1832, 2015 | 210 | 2015 |
Compression of Pancreatic Tumor Blood Vessels by Hyaluronan Is Caused by Solid Stress and Not Interstitial Fluid Pressure VP Chauhan, Y Boucher, CR Ferrone, S Roberge, JD Martin, ... Cancer Cell 26 (1), 14-15, 2014 | 202 | 2014 |
Reprogramming the microenvironment with tumor-selective angiotensin blockers enhances cancer immunotherapy VP Chauhan, IX Chen, R Tong, MR Ng, JD Martin, K Naxerova, MW Wu, ... Proceedings of the National Academy of Sciences 116 (22), 10674-10680, 2019 | 171 | 2019 |
Reengineering the Tumor Microenvironment to Alleviate Hypoxia and Overcome Cancer Heterogeneity JD Martin, D Fukumura, DG Duda, Y Boucher, RK Jain Cold Spring Harbor Perspectives in Medicine 6 (12), a027094, 2016 | 171 | 2016 |
TGF-β inhibition combined with cytotoxic nanomedicine normalizes triple negative breast cancer microenvironment towards anti-tumor immunity M Panagi, C Voutouri, F Mpekris, P Papageorgis, MR Martin, JD Martin, ... Theranostics 10 (4), 1910, 2020 | 135 | 2020 |