| Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response CS Manno, GF Pierce, VR Arruda, B Glader, M Ragni, JJE Rasko, ... Nature medicine 12 (3), 342-347, 2006 | 2417 | 2006 |
| Inhibition of hepatitis B virus in mice by RNA interference AP McCaffrey, H Nakai, K Pandey, Z Huang, FH Salazar, H Xu, ... Nature biotechnology 21 (6), 639-644, 2003 | 992 | 2003 |
| Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8 K Inagaki, S Fuess, TA Storm, GA Gibson, CF Mctiernan, MA Kay, H Nakai Molecular Therapy 14 (1), 45-53, 2006 | 729 | 2006 |
| Extrachromosomal recombinant adeno-associated virus vector genomes are primarily responsible for stable liver transduction in vivo H Nakai, SR Yant, TA Storm, S Fuess, L Meuse, MA Kay Journal of virology 75 (15), 6969-6976, 2001 | 570 | 2001 |
| AAV serotype 2 vectors preferentially integrate into active genes in mice H Nakai, E Montini, S Fuess, TA Storm, M Grompe, MA Kay Nature genetics 34 (3), 297-302, 2003 | 465 | 2003 |
| Unrestricted hepatocyte transduction with adeno-associated virus serotype 8 vectors in mice H Nakai, S Fuess, TA Storm, S Muramatsu, Y Nara, MA Kay Journal of virology 79 (1), 214-224, 2005 | 424 | 2005 |
| Characterization of genome integrity for oversized recombinant AAV vector B Dong, H Nakai, W Xiao Molecular therapy 18 (1), 87-92, 2010 | 263 | 2010 |
| Increasing the size of rAAV-mediated expression cassettes in vivo by intermolecular joining of two complementary vectors H Nakai, TA Storm, MA Kay Nature biotechnology 18 (5), 527-532, 2000 | 254 | 2000 |
| Preclinical in vivo evaluation of pseudotyped adeno-associated virus vectors for liver gene therapy D Grimm, S Zhou, H Nakai, CE Thomas, TA Storm, S Fuess, T Matsushita, ... Blood 102 (7), 2412-2419, 2003 | 253 | 2003 |
| Recruitment of single-stranded recombinant adeno-associated virus vector genomes and intermolecular recombination are responsible for stable transduction of liver in vivo H Nakai, TA Storm, MA Kay Journal of virology 74 (20), 9451-9463, 2000 | 246 | 2000 |
| Large-scale molecular characterization of adeno-associated virus vector integration in mouse liver H Nakai, X Wu, S Fuess, TA Storm, D Munroe, E Montini, SM Burgess, ... Journal of virology 79 (6), 3606-3614, 2005 | 228 | 2005 |
| Sustained survival of human hepatocytes in mice: a model for in vivo infection with human hepatitis B and hepatitis delta viruses K Ohashi, PL Marion, H Nakai, L Meuse, JM Cullen, BB Bordier, ... Nature medicine 6 (3), 327-331, 2000 | 228 | 2000 |
| Adeno-associated viral vector-mediated gene transfer of human blood coagulation factor IX into mouse liver H Nakai, RW Herzog, JN Hagstrom, J Walter, SH Kung, EY Yang, SJ Tai, ... Blood, The Journal of the American Society of Hematology 91 (12), 4600-4607, 1998 | 227 | 1998 |
| Isolation of recombinant adeno-associated virus vector-cellular DNA junctions from mouse liver H Nakai, Y Iwaki, MA Kay, LB Couto Journal of virology 73 (7), 5438-5447, 1999 | 224 | 1999 |
| Drawing a high-resolution functional map of adeno-associated virus capsid by massively parallel sequencing K Adachi, T Enoki, Y Kawano, M Veraz, H Nakai Nature communications 5 (1), 1-14, 2014 | 194 | 2014 |
| Nonrandom transduction of recombinant adeno-associated virus vectors in mouse hepatocytes in vivo: cell cycling does not influence hepatocyte transduction CH Miao, H Nakai, AR Thompson, TA Storm, W Chiu, RO Snyder, MA Kay Journal of virology 74 (8), 3793-3803, 2000 | 172 | 2000 |
| Coexpression of factor VIII heavy and light chain adeno-associated viral vectors produces biologically active protein M Burton, H Nakai, P Colosi, J Cunningham, R Mitchell, L Couto Proceedings of the National Academy of Sciences 96 (22), 12725-12730, 1999 | 150 | 1999 |
| Liver transduction with recombinant adeno-associated virus is primarily restricted by capsid serotype not vector genotype D Grimm, K Pandey, H Nakai, TA Storm, MA Kay Journal of virology 80 (1), 426-439, 2006 | 148 | 2006 |
| TP53 mutations emerge at early phase of myelodysplastic syndrome and are associated with complex chromosomal abnormalities H Kaneko, S Misawa, S Horiike, H Nakai, K Kashima | 147 | 1995 |
| Adeno-associated virus (AAV) assembly-activating protein is not an essential requirement for capsid assembly of AAV serotypes 4, 5, and 11 LF Earley, JM Powers, K Adachi, JT Baumgart, NL Meyer, Q Xie, ... Journal of virology 91 (3), 10.1128/jvi. 01980-16, 2017 | 141 | 2017 |
