Discovery of a novel class of boron-based antibacterials with activity against gram-negative bacteria V Hernandez, T Crépin, A Palencia, S Cusack, T Akama, SJ Baker, W Bu, ... Antimicrobial agents and chemotherapy 57 (3), 1394-1403, 2013 | 213 | 2013 |
Structural dynamics of the aminoacylation and proofreading functional cycle of bacterial leucyl-tRNA synthetase A Palencia, T Crepin, MT Vu, TL Lincecum Jr, SA Martinis, S Cusack Nature structural & molecular biology 19 (7), 677-684, 2012 | 172 | 2012 |
A role for Fkbp6 and the chaperone machinery in piRNA amplification and transposon silencing J Xiol, E Cora, R Koglgruber, S Chuma, S Subramanian, M Hosokawa, ... Molecular cell 47 (6), 970-979, 2012 | 137 | 2012 |
Mutational and metal binding analysis of the endonuclease domain of the influenza virus polymerase PA subunit T Crépin, A Dias, A Palencia, C Swale, S Cusack, RWH Ruigrok Journal of virology 84 (18), 9096-9104, 2010 | 119 | 2010 |
Discovery of novel oral protein synthesis inhibitors of Mycobacterium tuberculosis that target leucyl-tRNA synthetase A Palencia, X Li, W Bu, W Choi, CZ Ding, EE Easom, L Feng, ... Antimicrobial agents and chemotherapy 60 (10), 6271-6280, 2016 | 112 | 2016 |
The physiological target for Leu RS translational quality control is norvaline N Cvetesic, A Palencia, I Halasz, S Cusack, I Gruic‐Sovulj The EMBO journal 33 (15), 1639-1653, 2014 | 91 | 2014 |
Structure and dynamics of the MKK7–JNK signaling complex J Kragelj, A Palencia, MH Nanao, D Maurin, G Bouvignies, M Blackledge, ... Proceedings of the National Academy of Sciences 112 (11), 3409-3414, 2015 | 78 | 2015 |
Thermodynamic dissection of the binding energetics of proline-rich peptides to the Abl-SH3 domain: implications for rational ligand design A Palencia, ES Cobos, PL Mateo, JC Martı́nez, I Luque Journal of molecular biology 336 (2), 527-537, 2004 | 78 | 2004 |
Antimalarial benzoxaboroles target Plasmodium falciparum leucyl-tRNA synthetase E Sonoiki, A Palencia, D Guo, V Ahyong, C Dong, X Li, VS Hernandez, ... Antimicrobial agents and chemotherapy 60 (8), 4886-4895, 2016 | 74 | 2016 |
Cryptosporidium and Toxoplasma parasites are inhibited by a benzoxaborole targeting leucyl-tRNA synthetase A Palencia, RJ Liu, M Lukarska, J Gut, A Bougdour, B Touquet, ED Wang, ... Antimicrobial agents and chemotherapy 60 (10), 5817-5827, 2016 | 69 | 2016 |
Deciphering the dynamic interaction profile of an intrinsically disordered protein by NMR exchange spectroscopy E Delaforge, J Kragelj, L Tengo, A Palencia, S Milles, G Bouvignies, ... Journal of the American Chemical Society 140 (3), 1148-1158, 2018 | 68 | 2018 |
Targeting Toxoplasma gondii CPSF3 as a new approach to control toxoplasmosis A Palencia, A Bougdour, MP Brenier‐Pinchart, B Touquet, RL Bertini, ... EMBO molecular medicine 9 (3), 385-394, 2017 | 66 | 2017 |
The multiple Tudor domain-containing protein TDRD1 is a molecular scaffold for mouse Piwi proteins and piRNA biogenesis factors N Mathioudakis, A Palencia, J Kadlec, A Round, K Tripsianes, M Sattler, ... Rna 18 (11), 2056-2072, 2012 | 63 | 2012 |
Metal-captured inhibition of pre-mRNA processing activity by CPSF3 controls Cryptosporidium infection C Swale, A Bougdour, A Gnahoui-David, J Tottey, S Georgeault, ... Science translational medicine 11 (517), eaax7161, 2019 | 54 | 2019 |
Structural basis for the subversion of MAP kinase signaling by an intrinsically disordered parasite secreted agonist E Pellegrini, A Palencia, L Braun, U Kapp, A Bougdour, H Belrhali, ... Structure 25 (1), 16-26, 2017 | 53 | 2017 |
Plant tumour biocontrol agent employs a tRNA-dependent mechanism to inhibit leucyl-tRNA synthetase S Chopra, A Palencia, C Virus, A Tripathy, BR Temple, ... Nature communications 4 (1), 1417, 2013 | 49 | 2013 |
Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl A Palencia, A Camara-Artigas, MT Pisabarro, JC Martinez, I Luque Journal of Biological Chemistry 285 (4), 2823-2833, 2010 | 40 | 2010 |
Visualizing protein breathing motions associated with aromatic ring flipping L Mariño Pérez, FS Ielasi, LM Bessa, D Maurin, J Kragelj, M Blackledge, ... Nature 602 (7898), 695-700, 2022 | 37 | 2022 |
Biochemical and biophysical characterization of the selenium-binding and reducing site in Arabidopsis thaliana homologue to mammals selenium-binding protein 1 F Schild, S Kieffer-Jaquinod, A Palencia, D Cobessi, G Sarret, C Zubieta, ... Journal of Biological Chemistry 289 (46), 31765-31776, 2014 | 37 | 2014 |
The RNA-binding region of human TRBP interacts with microRNA precursors through two independent domains MPMH Benoit, L Imbert, A Palencia, J Perard, C Ebel, J Boisbouvier, ... Nucleic acids research 41 (7), 4241-4252, 2013 | 37 | 2013 |