Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism H Zhao, L Yang, J Baddour, A Achreja, V Bernard, T Moss, JC Marini, ... elife 5, e10250, 2016 | 815 | 2016 |
Glutaminolysis: a hallmark of cancer metabolism L Yang, S Venneti, D Nagrath Annual review of biomedical engineering 19, 163-194, 2017 | 704 | 2017 |
The role of stromal cancer-associated fibroblasts in pancreatic cancer D Von Ahrens, TD Bhagat, D Nagrath, A Maitra, A Verma Journal of hematology & oncology 10, 1-8, 2017 | 402 | 2017 |
Reactive oxygen species in the tumor microenvironment: an overview F Weinberg, N Ramnath, D Nagrath Cancers 11 (8), 1191, 2019 | 367 | 2019 |
Targeting stromal glutamine synthetase in tumors disrupts tumor microenvironment-regulated cancer cell growth L Yang, A Achreja, TL Yeung, LS Mangala, D Jiang, C Han, J Baddour, ... Cell metabolism 24 (5), 685-700, 2016 | 361 | 2016 |
Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer L Yang, T Moss, LS Mangala, J Marini, H Zhao, S Wahlig, G Armaiz‐Pena, ... Molecular systems biology 10 (5), 728, 2014 | 351 | 2014 |
Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer P Dey, J Baddour, F Muller, CC Wu, H Wang, WT Liao, Z Lan, A Chen, ... Nature 542 (7639), 119-123, 2017 | 252 | 2017 |
Three-dimensional primary hepatocyte culture in synthetic self-assembling peptide hydrogel S Wang, D Nagrath, PC Chen, F Berthiaume, ML Yarmush Tissue Engineering Part A 14 (2), 227-236, 2008 | 206 | 2008 |
Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tumor development ZD Xiao, L Han, H Lee, L Zhuang, Y Zhang, J Baddour, D Nagrath, ... Nature communications 8 (1), 783, 2017 | 183 | 2017 |
Metabolic preconditioning of donor organs: defatting fatty livers by normothermic perfusion ex vivo D Nagrath, H Xu, Y Tanimura, R Zuo, F Berthiaume, M Avila, R Yarmush, ... Metabolic engineering 11 (4-5), 274-283, 2009 | 176 | 2009 |
The key role of extracellular vesicles in the metastatic process H Zhao, A Achreja, E Iessi, M Logozzi, D Mizzoni, R Di Raimo, D Nagrath, ... Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1869 (1), 64-77, 2018 | 158 | 2018 |
A switch in the source of ATP production and a loss in capacity to perform glycolysis are hallmarks of hepatocyte failure in advance liver disease T Nishikawa, N Bellance, A Damm, H Bing, Z Zhu, K Handa, MI Yovchev, ... Journal of hepatology 60 (6), 1203-1211, 2014 | 138 | 2014 |
The glucose‐deprivation network counteracts lapatinib‐induced toxicity in resistant ErbB2‐positive breast cancer cells K Komurov, JT Tseng, M Muller, EG Seviour, TJ Moss, L Yang, D Nagrath, ... Molecular systems biology 8 (1), 596, 2012 | 128 | 2012 |
Tumour-reprogrammed stromal BCAT1 fuels branched-chain ketoacid dependency in stromal-rich PDAC tumours Z Zhu, A Achreja, N Meurs, O Animasahun, S Owen, A Mittal, P Parikh, ... Nature Metabolism 2 (8), 775-792, 2020 | 123 | 2020 |
Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts TD Bhagat, D Von Ahrens, M Dawlaty, Y Zou, J Baddour, A Achreja, ... Elife 8, e50663, 2019 | 121 | 2019 |
Generation of systemic antitumour immunity via the in situ modulation of the gut microbiome by an orally administered inulin gel K Han, J Nam, J Xu, X Sun, X Huang, O Animasahun, A Achreja, JH Jeon, ... Nature biomedical engineering 5 (11), 1377-1388, 2021 | 118 | 2021 |
Oxygen uptake rates and liver‐specific functions of hepatocyte and 3T3 fibroblast co‐cultures CH Cho, J Park, D Nagrath, AW Tilles, F Berthiaume, M Toner, ... Biotechnology and bioengineering 97 (1), 188-199, 2007 | 117 | 2007 |
Human omental-derived adipose stem cells increase ovarian cancer proliferation, migration, and chemoresistance A Nowicka, FC Marini, TN Solley, PB Elizondo, Y Zhang, HJ Sharp, ... PloS one 8 (12), e81859, 2013 | 115 | 2013 |
Pyruvate uptake is increased in highly invasive ovarian cancer cells under anoikis conditions for anaplerosis, mitochondrial function, and migration CA Caneba, N Bellance, L Yang, L Pabst, D Nagrath American Journal of Physiology-Endocrinology and Metabolism 303 (8), E1036-E1052, 2012 | 110 | 2012 |
Nitric oxide: the forgotten child of tumor metabolism BS Rizi, A Achreja, D Nagrath Trends in cancer 3 (9), 659-672, 2017 | 105 | 2017 |