关注
Kristoffer R. Brandvold
Kristoffer R. Brandvold
Janssen
在 its.jnj.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Development of a highly selective c-Src kinase inhibitor
KR Brandvold, ME Steffey, CC Fox, MB Soellner
ACS chemical biology 7 (8), 1393-1398, 2012
1602012
The chemical biology of molecular chaperones—implications for modulation of proteostasis
KR Brandvold, RI Morimoto
Journal of molecular biology 427 (18), 2931-2947, 2015
1192015
Conformation-selective analogues of dasatinib reveal insight into kinase inhibitor binding and selectivity
FE Kwarcinski, KR Brandvold, S Phadke, OM Beleh, TK Johnson, ...
ACS chemical biology 11 (5), 1296-1304, 2016
762016
Development of a chimeric c-Src kinase and HDAC inhibitor
KS Ko, ME Steffey, KR Brandvold, MB Soellner
ACS medicinal chemistry letters 4 (8), 779-783, 2013
562013
A continuous fluorescence assay for simple quantification of bile salt hydrolase activity in the gut microbiome
KR Brandvold, JM Weaver, C Whidbey, AT Wright
Scientific Reports 9 (1), 1359, 2019
282019
UM-164: A Potent c-Src/p38 Kinase Inhibitor with In Vivo Activity against Triple-Negative Breast Cancer
RA Gilani, S Phadke, LW Bao, EJ Lachacz, ML Dziubinski, KR Brandvold, ...
Clinical Cancer Research 22 (20), 5087-5096, 2016
282016
Exquisitely specific bisubstrate inhibitors of c-Src kinase
KR Brandvold, SM Santos, ME Breen, EJ Lachacz, ME Steffey, ...
ACS chemical biology 10 (6), 1387-1391, 2015
282015
Activity‐Based Protein Profiling of Bile Salt Hydrolysis in the Human Gut Microbiome with Beta‐Lactam or Acrylamide‐Based Probes
KR Brandvold, CJ Miller, RF Volk, BJ Killinger, C Whidbey, AT Wright
ChemBioChem 22 (8), 1448-1455, 2021
142021
Profiling How the Gut Microbiome Modulates Host Xenobiotic Metabolism in Response to Benzo[a]pyrene and 1-Nitropyrene Exposure
WL Garcia, CJ Miller, GX Lomas, KA Gaither, KJ Tyrrell, JN Smith, ...
Chemical research in toxicology 35 (4), 585-596, 2022
132022
Ai-accelerated design of targeted covalent inhibitors for SARS-CoV-2
RP Joshi, KJ Schultz, JW Wilson, A Kruel, RA Varikoti, CJ Kombala, ...
Journal of Chemical Information and Modeling 63 (5), 1438-1453, 2023
112023
Simple analysis of primary and secondary bile salt hydrolysis in mouse and human gut microbiome samples by using fluorogenic substrates
A Sveistyte, T Gibbins, KJ Tyrrell, CJ Miller, MH Foley, AE Plymale, ...
ChemBioChem 21 (24), 3539-3543, 2020
92020
Bile salt hydrolase probe and method of making and using the same
AT Wright, KR Brandvold, S Ramos-Hunter
US Patent 11,155,573, 2021
82021
Who is metabolizing what? Discovering novel biomolecules in the microbiome and the organisms who make them
SP Couvillion, N Agrawal, SM Colby, KR Brandvold, TO Metz
Frontiers in Cellular and Infection Microbiology 10, 388, 2020
72020
Profiling rhythmicity of bile salt hydrolase activity in the gut lumen with a rapid fluorescence assay
CJ Kombala, N Agrawal, A Sveistyte, IN Karatsoreos, HPA Van Dongen, ...
Organic & Biomolecular Chemistry 21 (19), 4028-4038, 2023
52023
Chemoproteomic analyses by activity‐based protein profiling
BJ Killinger, KR Brandvold, SJ Ramos‐Hunter, AT Wright
Mass spectrometry‐based chemical proteomics, 67-99, 2019
32019
Integrated data-driven and experimental approaches to accelerate lead optimization targeting SARS-CoV-2 main protease
RA Varikoti, KJ Schultz, CJ Kombala, A Kruel, KR Brandvold, M Zhou, ...
Journal of Computer-Aided Molecular Design 37 (8), 339-355, 2023
22023
Bile salt hydrolase profiling by fluorogenic probes in the human gut microbiome
A Sveistyte, CJ Miller, KR Brandvold, AT Wright
Methods in Enzymology 664, 243-265, 2022
22022
Retraction: UM-164: A Potent c-Src/p38 Kinase Inhibitor with In Vivo Activity against Triple-Negative Breast Cancer
RA Gilani, S Phadke, LW Bao, EJ Lachacz, ML Dziubinski, KR Brandvold, ...
Clinical Cancer Research 26 (7), 1777-1777, 2020
12020
Lactobacillus acidophilus disrupts collaborative multispecies bile acid metabolism
S Dautel, N Khan, KR Brandvold, CJ Brislawn, J Hutchison, KK Weitz, ...
bioRxiv, 296020, 2018
12018
Improving kinase inhibitor selectivity through exploring adjacent non-conserved pockets
KR Brandvold, MB Soellner
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 242, 2011
12011
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