Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation R Khosravi-Far, PA Solski, GJ Clark, MS Kinch, CJ Der Molecular and cellular biology, 1995 | 906 | 1995 |
An analysis of FDA-approved drugs: natural products and their derivatives E Patridge, P Gareiss, MS Kinch, D Hoyer Drug discovery today 21 (2), 204-207, 2016 | 895 | 2016 |
Integrin-mediated cell adhesion activates mitogen-activated protein kinases. Q Chen, MS Kinch, TH Lin, K Burridge, RL Juliano Journal of Biological Chemistry 269 (43), 26602-26605, 1994 | 879 | 1994 |
Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation H Miao, E Burnett, M Kinch, E Simon, B Wang Nature cell biology 2 (2), 62-69, 2000 | 678 | 2000 |
EphA2 overexpression causes tumorigenesis of mammary epithelial cells DP Zelinski, ND Zantek, JC Stewart, AR Irizarry, MS Kinch Cancer research 61 (5), 2301-2306, 2001 | 611 | 2001 |
Tyrosine phosphorylation regulates the adhesions of ras-transformed breast epithelia. MS Kinch, GJ Clark, CJ Der, K Burridge The Journal of cell biology 130 (2), 461-471, 1995 | 398 | 1995 |
Molecular regulation of tumor cell vasculogenic mimicry by tyrosine phosphorylation: role of epithelial cell kinase (Eck/EphA2) AR Hess, EA Seftor, LMG Gardner, K Carles-Kinch, GB Schneider, ... Cancer research 61 (8), 3250-3255, 2001 | 375 | 2001 |
E-cadherin regulates the function of the EphA2 receptor tyrosine kinase ND Zantek, M Azimi, M Fedor-Chaiken, B Wang, R Brackenbury, ... | 370 | 1999 |
Overexpression of the EphA2 tyrosine kinase in prostate cancer J Walker‐Daniels, K Coffman, M Azimi, JS Rhim, DG Bostwick, P Snyder, ... The Prostate 41 (4), 275-280, 1999 | 333 | 1999 |
Predictive value of the EphA2 receptor tyrosine kinase in lung cancer recurrence and survival MS Kinch, MB Moore, DH Harpole Jr Clinical cancer research 9 (2), 613-618, 2003 | 316 | 2003 |
Antibody targeting of the EphA2 tyrosine kinase inhibits malignant cell behavior K Carles-Kinch, KE Kilpatrick, JC Stewart, MS Kinch Cancer research 62 (10), 2840-2847, 2002 | 298 | 2002 |
EphA2 expression is associated with aggressive features in ovarian carcinoma PH Thaker, M Deavers, J Celestino, A Thornton, MS Fletcher, CN Landen, ... Clinical Cancer Research 10 (15), 5145-5150, 2004 | 294 | 2004 |
An overview of FDA-approved new molecular entities: 1827–2013 MS Kinch, A Haynesworth, SL Kinch, D Hoyer Drug discovery today 19 (8), 1033-1039, 2014 | 269 | 2014 |
VE-cadherin regulates EphA2 in aggressive melanoma cells through a novel signaling pathway: implications for vasculogenic mimicry AR Hess, EA Seftor, LM Gruman, MS Kinch, REB Seftor, MJC Hendrix Cancer biology & therapy 5 (2), 228-233, 2006 | 242 | 2006 |
An overview of FDA-approved biologics medicines MS Kinch Drug discovery today 20 (4), 393-398, 2015 | 234 | 2015 |
The Ras-related protein Rheb is farnesylated and antagonizes Ras signaling and transformation GJ Clark, MS Kinch, K Rogers-Graham, SM Sebti, AD Hamilton, CJ Der Journal of Biological Chemistry 272 (16), 10608-10615, 1997 | 230 | 1997 |
Differential regulation of EphA2 in normal and malignant cells J Walker-Daniels, AR Hess, MJC Hendrix, MS Kinch The American journal of pathology 162 (4), 1037-1042, 2003 | 222 | 2003 |
Regulation of the EphA2 kinase by the low molecular weight tyrosine phosphatase induces transformation KD Kikawa, DR Vidale, RL Van Etten, MS Kinch Journal of Biological Chemistry 277 (42), 39274-39279, 2002 | 210 | 2002 |
c-Cbl-dependent EphA2 protein degradation is induced by ligand binding J Walker-Daniels, DJ Riese, MS Kinch Molecular cancer research 1 (1), 79-87, 2002 | 209 | 2002 |
Dynamic interaction of PTPμ with multiple cadherins in vivo SM Brady-Kalnay, T Mourton, JP Nixon, GE Pietz, M Kinch, H Chen, ... The Journal of cell biology 141 (1), 287-296, 1998 | 205 | 1998 |