| Discovery of quinoline small molecules with potent dispersal activity against methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis biofilms using a … Y Abouelhassan, AT Garrison, GM Burch, W Wong, VM Norwood IV, ... Bioorganic & Medicinal Chemistry Letters 24 (21), 5076-5080, 2014 | 86 | 2014 |
| Harnessing the chemistry of the indole heterocycle to drive discoveries in biology and medicine VM Norwood IV, RW Huigens III ChemBioChem 20 (18), 2273-2297, 2019 | 83 | 2019 |
| Structure–activity relationships of a diverse class of halogenated phenazines that targets persistent, antibiotic-tolerant bacterial biofilms and Mycobacterium tuberculosis AT Garrison, Y Abouelhassan, VM Norwood IV, D Kallifidas, F Bai, ... Journal of Medicinal Chemistry 59 (8), 3808-3825, 2016 | 81 | 2016 |
| A tryptoline ring‐distortion strategy leads to complex and diverse biologically active molecules from the indole alkaloid yohimbine NG Paciaroni, R Ratnayake, JH Matthews, VM Norwood IV, AC Arnold, ... Chemistry–A European Journal 23 (18), 4327-4335, 2017 | 76 | 2017 |
| Synthetically tuning the 2‐position of halogenated quinolines: Optimizing antibacterial and biofilm eradication activities via alkylation and reductive amination pathways A Basak, Y Abouelhassan, VM Norwood IV, F Bai, MT Nguyen, S Jin, ... Chemistry–A European Journal 22 (27), 9181-9189, 2016 | 40 | 2016 |
| A phytochemical–halogenated quinoline combination therapy strategy for the treatment of pathogenic bacteria Y Abouelhassan, AT Garrison, F Bai, VM Norwood IV, MT Nguyen, S Jin, ... ChemMedChem 10 (7), 1157-1162, 2015 | 37 | 2015 |
| Preventing morphine-seeking behavior through the re-engineering of vincamine’s biological activity VM Norwood IV, AC Brice-Tutt, SO Eans, HM Stacy, G Shi, R Ratnayake, ... Journal of medicinal chemistry 63 (10), 5119-5138, 2020 | 33 | 2020 |
| Re-engineering of yohimbine’s biological activity through ring distortion: identification and structure–activity relationships of a new class of antiplasmodial agents NG Paciaroni, DL Perry, VM Norwood IV, C Murillo-Solano, J Collins, ... ACS infectious diseases 6 (2), 159-167, 2020 | 23 | 2020 |
| Yohimbine as a starting point to access diverse natural product-like agents with re-programmed activities against cancer-relevant GPCR targets NG Paciaroni, VM Norwood IV, R Ratnayake, H Luesch, RW Huigens III Bioorganic & medicinal chemistry 28 (14), 115546, 2020 | 18 | 2020 |
| Halogenated quinolines bearing polar functionality at the 2-position: Identification of new antibacterial agents with enhanced activity against Staphylococcus epidermidis A Basak, Y Abouelhassan, YS Kim, VM Norwood IV, S Jin, RW Huigens III European Journal of Medicinal Chemistry 155, 705-713, 2018 | 16 | 2018 |
| Modular synthetic routes to fluorine-containing halogenated phenazine and acridine agents that induce rapid iron starvation in methicillin-resistant Staphylococcus aureus biofilms K Liu, M Brivio, T Xiao, VM Norwood IV, YS Kim, S Jin, A Papagni, L Vaghi, ... ACS infectious diseases 8 (2), 280-295, 2022 | 14 | 2022 |
| Ring distortion of vincamine leads to the identification of re-engineered antiplasmodial agents VM Norwood IV, C Murillo-Solano, MG Goertzen, BR Brummel, DL Perry, ... ACS omega 6 (31), 20455-20470, 2021 | 7 | 2021 |
| Microwave-enhanced, stereospecific ring-closure of medium-ring cyanamide ethers to yohimbine NG Paciaroni, VM Norwood IV, DE Garcia, RW Huigens III Tetrahedron Letters 60 (17), 1182-1185, 2019 | 2 | 2019 |
| Analogs of vincamine and uses thereof RW Huigens III, VM Norwood IV, H Luesch US Patent 11,130,764, 2021 | | 2021 |
| A Vincamine-Derived HCRTR2 Agonist Prevents Morphine-Seeking Behavior in Mouse Models D Trauner, NA Vepřek Synfacts 16 (06), 0724, 2020 | | 2020 |
| Ring Distortion of Vincamine Leads to Complex and Diverse Compounds for Drug Discovery R Huigens III, VM Norwood IV | | |
