Mycobacterium tuberculosis: success through dormancy M Gengenbacher, SHE Kaufmann FEMS microbiology reviews 36 (3), 514-532, 2012 | 889 | 2012 |
Nutrient-starved, non-replicating Mycobacterium tuberculosis requires respiration, ATP synthase and isocitrate lyase for maintenance of ATP homeostasis and viability M Gengenbacher, SPS Rao, K Pethe, T Dick Microbiology 156 (1), 81-87, 2010 | 306 | 2010 |
Absolute Proteome Composition and Dynamics during Dormancy and Resuscitation of Mycobacterium tuberculosis OT Schubert, C Ludwig, M Kogadeeva, M Zimmermann, G Rosenberger, ... Cell Host & Microbe, 2015 | 228 | 2015 |
The Mtb Proteome Library: A Resource of Assays to Quantify the Complete Proteome of Mycobacterium tuberculosis OT Schubert, J Mouritsen, C Ludwig, HL Röst, G Rosenberger, PK Arthur, ... Cell host & microbe 13 (5), 602-612, 2013 | 207 | 2013 |
Reduced drug uptake in phenotypically resistant nutrient-starved non-replicating Mycobacterium tuberculosis J Sarathy, V Dartois, T Dick, M Gengenbacher Antimicrobial Agents and Chemotherapy, 2013 | 159 | 2013 |
Rifabutin is active against Mycobacterium abscessus complex DB Aziz, JL Low, ML Wu, M Gengenbacher, JWP Teo, V Dartois, T Dick Antimicrobial agents and chemotherapy 61 (6), 10.1128/aac. 00155-17, 2017 | 135 | 2017 |
Central Memory CD4+ T Cells Are Responsible for the Recombinant Bacillus Calmette-Guérin ΔureC::hly Vaccine's Superior Protection Against Tuberculosis A Vogelzang, C Perdomo, U Zedler, S Kuhlmann, R Hurwitz, ... The Journal of infectious diseases 210 (12), 1928-1937, 2014 | 132 | 2014 |
Comprehensive insights into transcriptional adaptation of intracellular mycobacteria by microbe-enriched dual RNA sequencing RA Rienksma, M Suarez-Diez, HJ Mollenkopf, GM Dolganov, A Dorhoi, ... BMC genomics 16, 1-15, 2015 | 109 | 2015 |
Vitamin B6 biosynthesis is essential for survival and virulence of Mycobacterium tuberculosis T Dick, U Manjunatha, B Kappes, M Gengenbacher Molecular microbiology 78 (4), 980-988, 2010 | 106 | 2010 |
Pyrazinamide resistance is caused by two distinct mechanisms: prevention of Coenzyme A depletion and loss of virulence factor synthesis P Gopal, M Yee, J Sarathy, JL Low, JP Sarathy, F Kaya, V Dartois, ... ACS Infectious Diseases 2 (9), 616-626, 2016 | 101 | 2016 |
Integration of metabolomics and transcriptomics reveals a complex diet of Mycobacterium tuberculosis during early macrophage infection M Zimmermann, M Kogadeeva, M Gengenbacher, G McEwen, ... MSystems 2 (4), 10.1128/msystems. 00057-17, 2017 | 97 | 2017 |
Recombinant live vaccine candidates against tuberculosis SHE Kaufmann, M Gengenbacher Current opinion in biotechnology 23 (6), 900-907, 2012 | 95 | 2012 |
Vitamin B6 biosynthesis by the malaria parasite Plasmodium falciparum: biochemical and structural insights M Gengenbacher, TB Fitzpatrick, T Raschle, K Flicker, I Sinning, S Muller, ... Journal of Biological Chemistry 281 (6), 3633-3641, 2006 | 94 | 2006 |
The Recombinant BCG ΔureC::hly Vaccine Targets the AIM2 Inflammasome to Induce Autophagy and Inflammation H Saiga, N Nieuwenhuizen, M Gengenbacher, AB Koehler, S Schuerer, ... The Journal of infectious diseases 211 (11), 1831-1841, 2015 | 93 | 2015 |
Pyrazinamide triggers degradation of its target aspartate decarboxylase P Gopal, JP Sarathy, M Yee, P Ragunathan, J Shin, S Bhushan, J Zhu, ... Nature communications 11 (1), 1661, 2020 | 89 | 2020 |
CRISPRi chemical genetics and comparative genomics identify genes mediating drug potency in Mycobacterium tuberculosis S Li, NC Poulton, JS Chang, ZA Azadian, MA DeJesus, N Ruecker, ... Nature Microbiology 7 (6), 766-779, 2022 | 85 | 2022 |
The BCG replacement vaccine VPM1002: from drawing board to clinical trial SHE Kaufmann, MF Cotton, B Eisele, M Gengenbacher, L Grode, ... Expert review of vaccines 13 (5), 619-630, 2014 | 83 | 2014 |
Deletion of nuoG from the Vaccine Candidate Mycobacterium bovis BCG ΔureC::hly Improves Protection against Tuberculosis M Gengenbacher, N Nieuwenhuizen, A Vogelzang, H Liu, P Kaiser, ... MBio 7 (3), 10.1128/mbio. 00679-16, 2016 | 79 | 2016 |
Antigen 85C inhibition restricts Mycobacterium tuberculosis growth through disruption of cord factor biosynthesis T Warrier, M Tropis, J Werngren, A Diehl, M Gengenbacher, B Schlegel, ... Antimicrobial agents and chemotherapy 56 (4), 1735-1743, 2012 | 78 | 2012 |
Whole-cell screen of fragment library identifies gut microbiota metabolite indole propionic acid as antitubercular DA Negatu, JJJ Liu, M Zimmerman, F Kaya, V Dartois, CC Aldrich, ... Antimicrobial agents and chemotherapy 62 (3), 10.1128/aac. 01571-17, 2018 | 74 | 2018 |