| Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1 EL Mills, DG Ryan, HA Prag, D Dikovskaya, D Menon, Z Zaslona, ... Nature 556 (7699), 113-117, 2018 | 1344 | 2018 |
| Yeast creates a niche for symbiotic lactic acid bacteria through nitrogen overflow O Ponomarova, N Gabrielli, DC Sévin, M Mülleder, K Zirngibl, K Bulyha, ... Cell systems 5 (4), 345-357. e6, 2017 | 305 | 2017 |
| Bioaccumulation of therapeutic drugs by human gut bacteria M Klünemann, S Andrejev, S Blasche, A Mateus, P Phapale, ... Nature 597 (7877), 533-538, 2021 | 208 | 2021 |
| Inflating bacterial cells by increased protein synthesis M Basan, M Zhu, X Dai, M Warren, D Sévin, YP Wang, T Hwa Molecular systems biology 11 (10), 836, 2015 | 199 | 2015 |
| An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation RG Carroll, Z Zasłona, S Galván-Peña, EL Koppe, DC Sévin, S Angiari, ... Journal of Biological Chemistry 293 (15), 5509-5521, 2018 | 167 | 2018 |
| Nontargeted in vitro metabolomics for high-throughput identification of novel enzymes in Escherichia coli DC Sévin, T Fuhrer, N Zamboni, U Sauer Nature methods 14 (2), 187-194, 2017 | 161 | 2017 |
| Ubiquinone accumulation improves osmotic-stress tolerance in Escherichia coli DC Sévin, U Sauer Nature chemical biology 10 (4), 266-272, 2014 | 150 | 2014 |
| Biological insights through nontargeted metabolomics DC Sévin, A Kuehne, N Zamboni, U Sauer Current opinion in biotechnology 34, 1-8, 2015 | 144 | 2015 |
| Life span extension by targeting a link between metabolism and histone acetylation in Drosophila S Peleg, C Feller, I Forne, E Schiller, DC Sévin, T Schauer, C Regnard, ... EMBO reports 17 (3), 455-469, 2016 | 134 | 2016 |
| Genomewide landscape of gene–metabolome associations in Escherichia coli T Fuhrer, M Zampieri, DC Sévin, U Sauer, N Zamboni Molecular Systems Biology 13 (1), 907, 2017 | 132 | 2017 |
| Identifying drug targets in tissues and whole blood with thermal-shift profiling J Perrin, T Werner, N Kurzawa, A Rutkowska, DD Childs, M Kalxdorf, ... Nature Biotechnology 38 (3), 303-308, 2020 | 130 | 2020 |
| Global metabolic responses to salt stress in fifteen species DC Sévin, JN Stählin, GR Pollak, A Kuehne, U Sauer PLoS One 11 (2), e0148888, 2016 | 78 | 2016 |
| The bZIP transcription factors HY5 and HYH are positive regulators of the main nitrate reductase gene in Arabidopsis leaves, NIA2, but negative regulators of the nitrate … EM Jonassen, DC Sévin, C Lillo Journal of plant physiology 166 (18), 2071-2076, 2009 | 67 | 2009 |
| A dual control mechanism synchronizes riboflavin and sulphur metabolism in Bacillus subtilis DB Pedrolli, C Kühm, DC Sévin, MP Vockenhuber, U Sauer, B Suess, ... Proceedings of the National Academy of Sciences 112 (45), 14054-14059, 2015 | 44 | 2015 |
| The neurometabolic fingerprint of excessive alcohol drinking MW Meinhardt, DC Sévin, ML Klee, S Dieter, U Sauer, WH Sommer Neuropsychopharmacology 40 (5), 1259-1268, 2015 | 34 | 2015 |
| New insights into the mechanisms underlying 5-fluorouracil-induced intestinal toxicity based on transcriptomic and metabolomic responses in human intestinal organoids D Rodrigues, T de Souza, L Coyle, M Di Piazza, B Herpers, S Ferreira, ... Archives of Toxicology 95, 2691-2718, 2021 | 30 | 2021 |
| An integrated multiomic and quantitative label-free microscopy-based approach to study pro-fibrotic signalling in ex vivo human precision-cut lung slices MM Khan, D Poeckel, A Halavatyi, J Zukowska-Kasprzyk, F Stein, ... European Respiratory Journal 58 (1), 2021 | 27 | 2021 |
| Metabolic memory underlying minimal residual disease in breast cancer K Radic Shechter, E Kafkia, K Zirngibl, S Gawrzak, A Alladin, D Machado, ... Molecular Systems Biology 17 (10), e10141, 2021 | 20 | 2021 |
| Complementary NAD+ replacement strategies fail to functionally protect dystrophin-deficient muscle DW Frederick, AV McDougal, M Semenas, J Vappiani, A Nuzzo, JC Ulrich, ... Skeletal Muscle 10, 1-14, 2020 | 20 | 2020 |
| Metabolic network segmentation: A probabilistic graphical modeling approach to identify the sites and sequential order of metabolic regulation from non-targeted metabolomics data A Kuehne, U Mayr, DC Sévin, M Claassen, N Zamboni PLoS computational biology 13 (6), e1005577, 2017 | 11 | 2017 |
