关注
Timothy Tran
Timothy Tran
Columbia University
在 cornell.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Engineering and characterization of a superfolder green fluorescent protein
JD Pédelacq, S Cabantous, TH Tran, TC Terwilliger, GS Waldo
Nature biotechnology 24 (1), 79-88, 2006
25462006
Multivalent small-molecule pan-RAS inhibitors
ME Welsch, A Kaplan, JM Chambers, ME Stokes, PH Bos, A Zask, ...
Cell 168 (5), 878-889. e29, 2017
2672017
Structural basis of recognition of farnesylated and methylated KRAS4b by PDEδ
S Dharmaiah, L Bindu, TH Tran, WK Gillette, PH Frank, R Ghirlando, ...
Proceedings of the National Academy of Sciences 113 (44), E6766-E6775, 2016
1802016
Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer
GA Hobbs, NM Baker, AM Miermont, RD Thurman, M Pierobon, TH Tran, ...
Cancer discovery 10 (1), 104-123, 2020
1612020
KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation
TH Tran, AH Chan, LC Young, L Bindu, C Neale, S Messing, ...
Nature communications 12 (1), 1176, 2021
1412021
Toxic waste disposal in Escherichia coli
RB Helling, BK Janes, H Kimball, TH Tran, M Bundesmann, P Check, ...
Journal of bacteriology 184 (13), 3699-3703, 2002
1092002
KRAS G13D sensitivity to neurofibromin-mediated GTP hydrolysis
D Rabara, TH Tran, S Dharmaiah, RM Stephens, F McCormick, ...
Proceedings of the National Academy of Sciences 116 (44), 22122-22131, 2019
1012019
Discovery of new classes of compounds that reactivate acetylcholinesterase inhibited by organophosphates
FS Katz, S Pecic, TH Tran, I Trakht, L Schneider, Z Zhu, L Ton‐That, ...
ChemBioChem 16 (15), 2205-2215, 2015
812015
Structural evidence of amyloid fibril formation in the putative aggregation domain of TDP-43
M Mompeán, R Hervás, Y Xu, TH Tran, C Guarnaccia, E Buratti, F Baralle, ...
The journal of physical chemistry letters 6 (13), 2608-2615, 2015
792015
Machine learning–driven multiscale modeling reveals lipid-dependent dynamics of RAS signaling proteins
HI Ingólfsson, C Neale, TS Carpenter, R Shrestha, CA López, TH Tran, ...
Proceedings of the National Academy of Sciences 119 (1), e2113297119, 2022
642022
Structures of N-terminally processed KRAS provide insight into the role of N-acetylation
S Dharmaiah, TH Tran, S Messing, C Agamasu, WK Gillette, W Yan, ...
Scientific reports 9 (1), 10512, 2019
582019
The small molecule BI-2852 induces a nonfunctional dimer of KRAS
TH Tran, P Alexander, S Dharmaiah, C Agamasu, DV Nissley, ...
Proceedings of the National Academy of Sciences 117 (7), 3363-3364, 2020
562020
KRAS prenylation is required for bivalent binding with calmodulin in a nucleotide-independent manner
C Agamasu, R Ghirlando, T Taylor, S Messing, TH Tran, L Bindu, ...
Biophysical journal 116 (6), 1049-1063, 2019
502019
Uncovering a membrane-distal conformation of KRAS available to recruit RAF to the plasma membrane
QN Van, CA López, M Tonelli, T Taylor, B Niu, CB Stanley, D Bhowmik, ...
Proceedings of the National Academy of Sciences 117 (39), 24258-24268, 2020
412020
Structure and function of a single-chain, multi-domain long-chain acyl-CoA carboxylase
TH Tran, YS Hsiao, J Jo, CY Chou, LEP Dietrich, T Walz, L Tong
Nature 518 (7537), 120-124, 2015
372015
LAG3 ectodomain structure reveals functional interfaces for ligand and antibody recognition
Q Ming, DP Celias, C Wu, AR Cole, S Singh, C Mason, S Dong, TH Tran, ...
Nature immunology 23 (7), 1031-1041, 2022
352022
NMR signal quenching from bound biradical affinity reagents in DNP samples
R Rogawski, IV Sergeyev, Y Zhang, TH Tran, Y Li, L Tong, AE McDermott
The Journal of Physical Chemistry B 121 (48), 10770-10781, 2017
332017
A novel mechanism of sulfur transfer catalyzed by O-acetylhomoserine sulfhydrylase in the methionine-biosynthetic pathway of Wolinella succinogenes
TH Tran, K Krishnamoorthy, TP Begley, SE Ealick
Acta Crystallographica Section D: Biological Crystallography 67 (10), 831-838, 2011
302011
Crystal structures of malonyl-coenzyme A decarboxylase provide insights into its catalytic mechanism and disease-causing mutations
DS Froese, F Forouhar, TH Tran, M Vollmar, YS Kim, S Lew, H Neely, ...
Structure 21 (7), 1182-1192, 2013
202013
The Crystal Structure of Streptococcus pyogenes Uridine Phosphorylase Reveals a Distinct Subfamily of Nucleoside Phosphorylases
TH Tran, S Christoffersen, PW Allan, WB Parker, J Piskur, I Serra, ...
Biochemistry 50 (30), 6549-6558, 2011
192011
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