Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins O Rozenblatt-Rosen, RC Deo, M Padi, G Adelmant, MA Calderwood, ... Nature 487 (7408), 491-495, 2012 | 422 | 2012 |
Improved detection suggests all Merkel cell carcinomas harbor Merkel polyomavirus SJ Rodig, J Cheng, J Wardzala, A DoRosario, JJ Scanlon, AC Laga, ... The Journal of Clinical Investigation, 2012 | 253 | 2012 |
Cellular transformation by simian virus 40 and murine polyoma virus T antigens J Cheng, JA DeCaprio, MM Fluck, BS Schaffhausen Seminars in cancer biology 19 (4), 218-228, 2009 | 216 | 2009 |
Merkel cell polyomavirus large T antigen has growth-promoting and inhibitory activities J Cheng, O Rozenblatt-Rosen, KG Paulson, P Nghiem, JA DeCaprio Journal of virology 87 (11), 6118-6126, 2013 | 157 | 2013 |
Tumor-specific T cells in human Merkel cell carcinomas: a possible role for Tregs and T-cell exhaustion in reducing T-cell responses M Dowlatshahi, V Huang, AE Gehad, Y Jiang, A Calarese, JE Teague, ... Journal of Investigative Dermatology 133 (7), 1879-1889, 2013 | 127 | 2013 |
Merkel cell polyomavirus exhibits dominant control of the tumor genome and transcriptome in virus-associated Merkel cell carcinoma GJ Starrett, C Marcelus, PG Cantalupo, JP Katz, J Cheng, K Akagi, ... MBio 8 (1), 10.1128/mbio. 02079-16, 2017 | 117 | 2017 |
Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis J Cheng, DE Park, C Berrios, EA White, R Arora, R Yoon, T Branigan, ... PLoS pathogens 13 (10), e1006668, 2017 | 116 | 2017 |
Clinical and molecular characterization of virus-positive and virus-negative Merkel cell carcinoma GJ Starrett, M Thakuria, T Chen, C Marcelus, J Cheng, J Nomburg, ... Genome medicine 12, 1-22, 2020 | 96 | 2020 |
Dual inhibition of MDM2 and MDM4 in virus-positive Merkel cell carcinoma enhances the p53 response DE Park, J Cheng, C Berrios, J Montero, M Cortés-Cros, S Ferretti, ... Proceedings of the National Academy of Sciences 116 (3), 1027-1032, 2019 | 92 | 2019 |
Merkel cell polyomavirus small T antigen promotes pro-glycolytic metabolic perturbations required for transformation C Berrios, M Padi, MA Keibler, DE Park, V Molla, J Cheng, SM Lee, ... PLoS pathogens 12 (11), e1006020, 2016 | 85 | 2016 |
Tumorigenic activity of merkel cell polyomavirus T antigens expressed in the stratified epithelium of mice ME Spurgeon, J Cheng, RT Bronson, PF Lambert, JA DeCaprio Cancer research 75 (6), 1068-1079, 2015 | 84 | 2015 |
A functional serine 118 phosphorylation site in estrogen receptor-α is required for down-regulation of gene expression by 17β-estradiol and 4-hydroxytamoxifen J Cheng, C Zhang, DJ Shapiro Endocrinology 148 (10), 4634-4641, 2007 | 82 | 2007 |
Identification of FAM111A as an SV40 host range restriction and adenovirus helper factor DA Fine, O Rozenblatt-Rosen, M Padi, A Korkhin, RL James, G Adelmant, ... Public Library of Science 8 (10), e1002949, 2012 | 74 | 2012 |
A new small molecule inhibitor of estrogen receptor α binding to estrogen response elements blocks estrogen-dependent growth of cancer cells C Mao, NM Patterson, MT Cherian, IO Aninye, C Zhang, JB Montoya, ... Journal of Biological Chemistry 283 (19), 12819-12830, 2008 | 73 | 2008 |
Merkel cell polyomavirus activates LSD1-mediated blockade of non-canonical BAF to regulate transformation and tumorigenesis DE Park, J Cheng, JP McGrath, MY Lim, C Cushman, SK Swanson, ... Nature cell biology 22 (5), 603-615, 2020 | 67 | 2020 |
Malawi polyomavirus is a prevalent human virus that interacts with known tumor suppressors C Berrios, J Jung, B Primi, M Wang, C Pedamallu, F Duke, C Marcelus, ... Journal of virology 89 (1), 857-862, 2015 | 32 | 2015 |
Tamoxifen induction of CCAAT enhancer-binding protein α is required for tamoxifen-induced apoptosis J Cheng, VY David, JH Zhou, DJ Shapiro Journal of Biological Chemistry 282 (42), 30535-30543, 2007 | 21 | 2007 |
An initiator and its flanking elements function as a core promoter driving transcription of the Hepatopoietin gene Y Zhao, F Tang, J Cheng, L Li, G Xing, Y Zhu, L Zhang, H Wei, F He FEBS letters 540 (1-3), 58-64, 2003 | 21 | 2003 |
Reversal of viral and epigenetic HLA class I repression in Merkel cell carcinoma PC Lee, S Klaeger, PM Le, K Korthauer, J Cheng, ... The Journal of clinical investigation 132 (13), 2022 | 17 | 2022 |
Merkel cell polyomavirus large T antigen binding to pRb promotes skin hyperplasia and tumor development ME Spurgeon, J Cheng, E Ward-Shaw, FA Dick, JA DeCaprio, ... PLoS Pathogens 18 (5), e1010551, 2022 | 17 | 2022 |