| Pharmacokinetics and pharmacodynamics of oral oxycodone in healthy human subjects: role of circulating active metabolites B Lalovic, E Kharasch, C Hoffer, L Risler, LY Liu‐Chen, DD Shen Clinical pharmacology & therapeutics 79 (5), 461-479, 2006 | 566 | 2006 |
| Comparison of pharmacological activities of buprenorphine and norbuprenorphine: norbuprenorphine is a potent opioid agonist P Huang, GB Kehner, A Cowan, LY Liu-Chen Journal of Pharmacology and Experimental Therapeutics 297 (2), 688-695, 2001 | 427 | 2001 |
| Molecular cloning and expression of a rat κ opioid receptor S Li, J Zhu, C Chen, YW Chen, JK Deriel, B Ashby, LY Liu-Chen Biochemical Journal 295 (3), 629-633, 1993 | 275 | 1993 |
| Comparison of pharmacological activities of three distinct κ ligands (salvinorin A, TRK-820 and 3FLB) on κ opioid receptors in vitro and their antipruritic and antinociceptive … Y Wang, K Tang, S Inan, D Siebert, U Holzgrabe, DYW Lee, P Huang, ... Journal of Pharmacology and Experimental Therapeutics 312 (1), 220-230, 2005 | 220 | 2005 |
| The association of NHERF adaptor proteins with G protein–coupled receptors and receptor tyrosine kinases EJ Weinman, RA Hall, PA Friedman, LY Liu-Chen, S Shenolikar Annu. Rev. Physiol. 68, 491-505, 2006 | 207 | 2006 |
| Heterodimerization and cross-desensitization between the μ-opioid receptor and the chemokine CCR5 receptor C Chen, J Li, G Bot, I Szabo, TJ Rogers, LY Liu-Chen European journal of pharmacology 483 (2-3), 175-186, 2004 | 200 | 2004 |
| Immunohistochemical evidence for a substance P-containing trigeminovascular pathway to pial arteries in cats LY Liu-Chen, MR Mayberg, MA Moskowitz Brain research 268 (1), 162-166, 1983 | 200 | 1983 |
| Mouse model of OPRM1 (A118G) polymorphism has sex-specific effects on drug-mediated behavior SD Mague, C Isiegas, P Huang, LY Liu-Chen, C Lerman, JA Blendy Proceedings of the National Academy of Sciences 106 (26), 10847-10852, 2009 | 198 | 2009 |
| U50, 488H-induced internalization of the human κ opioid receptor involves a β-arrestin-and dynamin-dependent mechanism: κ receptor internalization is not required for mitogen … JG Li, LY Luo, JG Krupnick, JL Benovic, LY Liu-Chen Journal of Biological Chemistry 274 (17), 12087-12094, 1999 | 194 | 1999 |
| Activation of the cloned human kappa opioid receptor by agonists enhances [35S] GTPγS binding to membranes: determination of potencies and efficacies of ligands J Zhu, LY Luo, JG Li, C Chen, LY Liu-Chen Journal of Pharmacology and Experimental Therapeutics 282 (2), 676-684, 1997 | 184 | 1997 |
| Differential binding domains of peptide and non-peptide ligands in the cloned rat kappa opioid receptor. JC Xue, C Chen, J Zhu, S Kunapuli, JK DeRiel, L Yu, LY Liu-Chen Journal of Biological Chemistry 269 (48), 30195-30199, 1994 | 175 | 1994 |
| Mutational analysis of Gβγ and phospholipid interaction with G protein-coupled receptor kinase 2 CV Carman, LS Barak, C Chen, LY Liu-Chen, JJ Onorato, SP Kennedy, ... Journal of Biological Chemistry 275 (14), 10443-10452, 2000 | 149 | 2000 |
| In vitro release of immunoreactive substance P from putative afferent nerve endings in bovine pia arachnoid MA Moskowitz, M Brody, LY Liu-Chen Neuroscience 9 (4), 809-814, 1983 | 146 | 1983 |
| Cloning of a human κ opioid receptor from the brain J Zhu, C Chen, JC Xue, S Kunapuli, JK DeRiel, LY Liu-Chen Life sciences 56 (9), PL201-PL207, 1995 | 143 | 1995 |
| 6′-Guanidinonaltrindole (6′-GNTI) is a G protein-biased κ-opioid receptor agonist that inhibits arrestin recruitment ML Rives, M Rossillo, LY Liu-Chen, JA Javitch Journal of Biological Chemistry 287 (32), 27050-27054, 2012 | 141 | 2012 |
| A common single nucleotide polymorphism A118G of the μ opioid receptor alters its N-glycosylation and protein stability P Huang, C Chen, SD Mague, JA Blendy, LY Liu-Chen Biochemical Journal 441 (1), 379-386, 2012 | 141 | 2012 |
| Dual ultrastructural immunocytochemical labeling of μ and δ opioid receptors in the superficial layers of the rat cervical spinal cord PY Cheng, LY Liu-Chen, VM Pickel Brain research 778 (2), 367-380, 1997 | 140 | 1997 |
| Ezrin-radixin-moesin-binding phosphoprotein-50/Na+/H+ exchanger regulatory factor (EBP50/NHERF) blocks U50, 488H-induced down-regulation of the human κ opioid receptor by … JG Li, C Chen, LY Liu-Chen Journal of Biological Chemistry 277 (30), 27545-27552, 2002 | 138 | 2002 |
| Agonist-induced regulation and trafficking of κ opioid receptors LY Liu-Chen Life sciences 75 (5), 511-536, 2004 | 130 | 2004 |
| Mephedrone (‘bath salt’) elicits conditioned place preference and dopamine-sensitive motor activation R Lisek, W Xu, E Yuvasheva, YT Chiu, AB Reitz, LY Liu-Chen, SM Rawls Drug and alcohol dependence 126 (1-2), 257-262, 2012 | 127 | 2012 |
