NASH limits anti-tumour surveillance in immunotherapy-treated HCC D Pfister, NG Núñez, R Pinyol, O Govaere, M Pinter, M Szydlowska, ... Nature 592 (7854), 450-456, 2021 | 848 | 2021 |
Single-cell mapping of human brain cancer reveals tumor-specific instruction of tissue-invading leukocytes E Friebel, K Kapolou, S Unger, NG Núñez, S Utz, EJ Rushing, L Regli, ... Cell 181 (7), 1626-1642. e20, 2020 | 448 | 2020 |
CD39 Expression Defines Cell Exhaustion in Tumor-Infiltrating CD8+ T Cells FP Canale, MC Ramello, N Núñez, CLA Furlan, SN Bossio, MG Serrán, ... Cancer research 78 (1), 115-128, 2018 | 363 | 2018 |
The DUX4 gene at the FSHD1A locus encodes a pro-apoptotic protein V Kowaljow, A Marcowycz, E Ansseau, CB Conde, S Sauvage, C Mattéotti, ... Neuromuscular Disorders 17 (8), 611-623, 2007 | 356 | 2007 |
Transcriptional and functional analysis of CD1c+ human dendritic cells identifies a CD163+ subset priming CD8+ CD103+ T cells P Bourdely, G Anselmi, K Vaivode, RN Ramos, Y Missolo-Koussou, ... Immunity 53 (2), 335-352. e8, 2020 | 259 | 2020 |
Tissue-resident FOLR2+ macrophages associate with CD8+ T cell infiltration in human breast cancer RN Ramos, Y Missolo-Koussou, Y Gerber-Ferder, CP Bromley, M Bugatti, ... Cell 185 (7), 1189-1207. e25, 2022 | 234 | 2022 |
Intratumoral IL-12 delivery empowers CAR-T cell immunotherapy in a pre-clinical model of glioblastoma G Agliardi, AR Liuzzi, A Hotblack, D De Feo, N Núñez, CL Stowe, ... Nature communications 12 (1), 444, 2021 | 193 | 2021 |
Development, application and computational analysis of high-dimensional fluorescent antibody panels for single-cell flow cytometry J Brummelman, C Haftmann, NG Nunez, G Alvisi, EMC Mazza, B Becher, ... Nature protocols 14 (7), 1946-1969, 2019 | 171 | 2019 |
Tumor invasion in draining lymph nodes is associated with Treg accumulation in breast cancer patients NG Núñez, J Tosello Boari, RN Ramos, W Richer, N Cagnard, ... Nature communications 11 (1), 3272, 2020 | 141 | 2020 |
Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas K Aslan, V Turco, J Blobner, JK Sonner, AR Liuzzi, NG Núñez, D De Feo, ... Nature communications 11 (1), 931, 2020 | 136 | 2020 |
Trisomy 21 dysregulates T cell lineages toward an autoimmunity-prone state associated with interferon hyperactivity P Araya, KA Waugh, KD Sullivan, NG Núñez, E Roselli, KP Smith, ... Proceedings of the National Academy of Sciences 116 (48), 24231-24241, 2019 | 103 | 2019 |
Distinct immunological signatures discriminate severe COVID-19 from non-SARS-CoV-2-driven critical pneumonia S Kreutmair, S Unger, NG Núñez, F Ingelfinger, C Alberti, D De Feo, ... Immunity 54 (7), 1578-1593. e5, 2021 | 90 | 2021 |
Induction of anergic or regulatory tumor-specific CD4+ T cells in the tumor-draining lymph node R Alonso, H Flament, S Lemoine, C Sedlik, E Bottasso, I Péguillet, ... Nature communications 9 (1), 2113, 2018 | 88 | 2018 |
IL-17 controls central nervous system autoimmunity through the intestinal microbiome T Regen, S Isaac, A Amorim, NG Núñez, J Hauptmann, ... Science immunology 6 (56), eaaz6563, 2021 | 83 | 2021 |
Graft-versus-host disease, but not graft-versus-leukemia immunity, is mediated by GM-CSF–licensed myeloid cells S Tugues, A Amorim, S Spath, G Martin-Blondel, B Schreiner, D De Feo, ... Science translational medicine 10 (469), eaat8410, 2018 | 81 | 2018 |
Conventional NK cells and tissue-resident ILC1s join forces to control liver metastasis L Ducimetière, G Lucchiari, G Litscher, M Nater, L Heeb, NG Nuñez, ... Proceedings of the National Academy of Sciences 118 (27), e2026271118, 2021 | 78 | 2021 |
Helminth antigens enable CpG-activated dendritic cells to inhibit the symptoms of collagen-induced arthritis through Foxp3+ regulatory T cells F Carranza, CR Falcón, N Nuñez, C Knubel, SG Correa, I Bianco, ... PloS one 7 (7), e40356, 2012 | 77 | 2012 |
CD8+ T cells retain protective functions despite sustained inhibitory receptor expression during Epstein-Barr virus infection in vivo B Chatterjee, Y Deng, A Holler, N Nunez, T Azzi, LD Vanoaica, A Müller, ... PLoS pathogens 15 (5), e1007748, 2019 | 71 | 2019 |
Anti-human CD117 CAR T-cells efficiently eliminate healthy and malignant CD117-expressing hematopoietic cells R Myburgh, JD Kiefer, NF Russkamp, CF Magnani, N Nuñez, A Simonis, ... Leukemia 34 (10), 2688-2703, 2020 | 66 | 2020 |
Phenotype of NK-like CD8 (+) T cells with innate features in humans and their relevance in cancer diseases A Barbarin, E Cayssials, F Jacomet, NG Nunez, S Basbous, L Lefèvre, ... Frontiers in immunology 8, 316, 2017 | 66 | 2017 |