Protein geranylgeranylation, not farnesylation, is required for the G1 to S phase transition in mouse fibroblasts. A Vogt, Y Qian, TF McGuire, AD Hamilton, SM Sebti Oncogene 13 (9), 1991-1999, 1996 | 220 | 1996 |
Cryo-EM structure of the human cannabinoid receptor CB2-Gi signaling complex C Xing, Y Zhuang, TH Xu, Z Feng, XE Zhou, M Chen, L Wang, X Meng, ... Cell 180 (4), 645-654. e13, 2020 | 215 | 2020 |
p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis H Cha-Molstad, JE Yu, Z Feng, SH Lee, JG Kim, P Yang, B Han, KW Sung, ... Nature communications 8 (1), 102, 2017 | 201 | 2017 |
Importance of MEK-1/-2 signaling in monocytic and granulocytic differentiation of myeloid cell lines MB Miranda, TF McGuire, DE Johnson Leukemia 16 (4), 683-692, 2002 | 197 | 2002 |
Vitamin D3-induced apoptosis of murine squamous cell carcinoma cells: selective induction of caspase-dependent MEK cleavage and up-regulation of MEKK-1 TF McGuire, DL Trump, CS Johnson Journal of Biological Chemistry 276 (28), 26365-26373, 2001 | 175 | 2001 |
Platelet-derived growth factor receptor tyrosine phosphorylation requires protein geranylgeranylation but not farnesylation TF McGuire, Y Qian, A Vogt, AD Hamilton, SM Sebti Journal of Biological Chemistry 271 (44), 27402-27407, 1996 | 148 | 1996 |
Combination of 1α,25-Dihydroxyvitamin D3 with Dexamethasone Enhances Cell Cycle Arrest and Apoptosis: Role of Nuclear Receptor Cross-Talk and Erk/Akt … RJ Bernardi, DL Trump, WD Yu, TF McGuire, PA Hershberger, ... Clinical cancer research 7 (12), 4164-4173, 2001 | 135 | 2001 |
Cisplatin Potentiates 1,25-Dihydroxyvitamin D3-induced Apoptosis in Association with Increased Mitogen-activated Protein Kinase Kinase Kinase 1 (MEKK-1 … PA Hershberger, TF McGuire, WD Yu, EG Zuhowski, JHM Schellens, ... Molecular cancer therapeutics 1 (10), 821-829, 2002 | 118 | 2002 |
Proteasome inhibition leads to significant reduction of Bcr-Abl expression and subsequent induction of apoptosis in K562 human chronic myelogenous leukemia cells QP Dou, TF McGuire, Y Peng, B An Journal of Pharmacology and Experimental Therapeutics 289 (2), 781-790, 1999 | 88 | 1999 |
Inhibition of protein geranylgeranylation causes a superinduction of nitric-oxide synthase-2 by interleukin-1β in vascular smooth muscle cells JD Finder, JL Litz, MA Blaskovich, TF McGuire, Y Qian, AD Hamilton, ... Journal of Biological Chemistry 272 (21), 13484-13488, 1997 | 87 | 1997 |
Lovastatin disrupts early events in insulin signaling: A potential mechanism of lovastatins anti-mitogenic activity TF Mcguire, XQ Xu, SJ Corey, GG Romero, SM Sebti Biochemical and biophysical research communications 204 (1), 399-406, 1994 | 66 | 1994 |
Lovastatin inhibits platelet-derived growth factor (PDGF) stimulation of phosphatidylinositol 3-kinase activity as well as association of p85 subunit to tyrosine-phosphorylated … TF McGuire, SJ Corey, SM Sebti Journal of Biological Chemistry 268 (30), 22227-22230, 1993 | 61 | 1993 |
Vitamin D receptor: a potential target for intervention CS Johnson, PA Hershberger, RJ Bernardi, TF Mcguire, DL Trump Urology 60 (3), 123-130, 2002 | 57 | 2002 |
Lovastatin inhibits the stimulation of mitogen-activated protein kinase by insulin in HIRcB fibroblasts X Xu, TF McGuire, MA Blaskovich, SM Sebti, G Romero Archives of biochemistry and biophysics 326 (2), 233-237, 1996 | 55 | 1996 |
Regulation of autophagic proteolysis by the N-recognin SQSTM1/p62 of the N-end rule pathway H Cha-Molstad, SH Lee, JG Kim, KW Sung, J Hwang, SM Shim, ... Autophagy 14 (2), 359-361, 2018 | 39 | 2018 |
Geranylgeraniol potentiates lovastatin inhibition of oncogenic H-Ras processing and signaling while preventing cytotoxicity TF McGuire, SM Sebti Oncogene 14 (3), 305-312, 1997 | 31 | 1997 |
Androgen receptor in rat liver: characterization and separation from a male-specific estrogen-binding protein PK Eagon, SM Seguiti, BJ Rogerson, TF McGuire, LE Porter, DH Seeley Archives of biochemistry and biophysics 268 (1), 161-175, 1989 | 31 | 1989 |
In vivo evolution of tumor-derived endothelial cells TF McGuire, GB Sajithlal, J Lu, RD Nicholls, EV Prochownik PloS one 7 (5), e37138, 2012 | 24 | 2012 |
Endothelial‐like cells derived directly from human tumor xenografts GB Sajithlal, TF McGuire, J Lu, D Beer‐Stolz, EV Prochownik International journal of cancer 127 (10), 2268-2278, 2010 | 23 | 2010 |
CAAX peptidomimetic FTI-244 decreases platelet-derived growth factor receptor tyrosine phosphorylation levels and inhibits stimulation of phosphatidylinositol 3-kinase but not … TF McGuire, YM Qian, MA Blaskovich, RD Fossum, JZ Sun, T Marlowe, ... Biochemical and biophysical research communications 214 (1), 295-303, 1995 | 22 | 1995 |