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Lucas Silva Franco
Lucas Silva Franco
在 ufrj.br 的电子邮件经过验证
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c-Abl mediated tyrosine phosphorylation of Aha1 activates its co-chaperone function in cancer cells
DM Dunn, MR Woodford, AW Truman, SM Jensen, J Schulman, T Caza, ...
Cell reports 12 (6), 1006-1018, 2015
642015
Design, synthesis and biological evaluation of biphenylamide derivatives as Hsp90 C-terminal inhibitors
H Zhao, G Garg, J Zhao, E Moroni, A Girgis, LS Franco, S Singh, ...
European journal of medicinal chemistry 89, 442-466, 2015
492015
Chemical intuition in drug design and discovery
JGB Pedreira, LS Franco, EJ Barreiro
Current topics in medicinal chemistry 19 (19), 1679-1693, 2019
232019
The Magic Methyl and Its Tricks in Drug Discovery and Development
PSM Pinheiro, LS Franco, CAM Fraga
Pharmaceuticals 16 (8), 1157, 2023
222023
Identification of LASSBio-1945 as an inhibitor of SARS-CoV-2 main protease (M PRO) through in silico screening supported by molecular docking and a fragment-based pharmacophore …
LS Franco, RC Maia, EJ Barreiro
RSC medicinal chemistry 12 (1), 110-119, 2021
182021
Molecular hybridization: a powerful tool for multitarget drug discovery
P de Sena Murteira Pinheiro, LS Franco, TL Montagnoli, CAM Fraga
Expert Opinion on Drug Discovery 19 (4), 451-470, 2024
152024
Synthesis of 1,4‐Anthracene‐9,10‐dione Derivatives and Their Regulation of Nitric Oxide, IL‐1β and TNF‐α in Activated RAW264.7 Cells
TA Corrêa, CCS Alves, SBR Castro, EE Oliveira, LS Franco, AP Ferreira, ...
Chemical Biology & Drug Design 82 (4), 463-467, 2013
102013
Novel phosphatidylinositol 4-kinases III beta (PI4KIIIβ) inhibitors discovered by virtual screening using free energy models
NM Colodette, LS Franco, RC Maia, HH Fokoue, CMR Sant’Anna, ...
Journal of Computer-Aided Molecular Design 34, 1091-1103, 2020
62020
Discovery of putative dual inhibitor of tubulin and EGFR by phenotypic Approach on LASSBio-1586 homologs
G Barbosa, LGV Gelves, CMX Costa, LS Franco, JAL de Lima, ...
Pharmaceuticals 15 (8), 913, 2022
42022
Bioactive Amino-Quinazolines: Synthesis and Therapeutic Applications
LS Franco, PSM Pinheiro, MLC Barbosa
Journal of the Brazilian Chemical Society 35 (10), e-20240100, 2024
2024
Remapping the Chemical Space and the Pharmacological Space of Drugs: What Can We Expect from the Road Ahead?
LS Franco, BSM de Jesus, PSM Pinheiro, CAM Fraga
Pharmaceuticals 17 (6), 742, 2024
2024
LASSBio Chemical Library Diversity and FLT3 New Ligand Identification
LS Franco, RC Maia, EJ Barreiro
Journal of the Brazilian Chemical Society 35 (10), e-20240059, 2024
2024
Stereochemical insights into β-amino-N-acylhydrazones and their impact on DPP-4 inhibition
E Reina, LS Franco, TR Carneiro, EJ Barreiro, LM Lima
RSC advances 14 (10), 6617-6626, 2024
2024
LASSBio Chemical Library: molecular properties profile and repurposing studies
LS Franco, R do Maia, EJ Barreiro
Galoá, 2022
2022
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