| Chemical evolution of natural product structure M Grigalunas, S Brakmann, H Waldmann Journal of the American Chemical Society 144 (8), 3314-3329, 2022 | 130 | 2022 |
| Natural product fragment combination to performance-diverse pseudo-natural products M Grigalunas, A Burhop, S Zinken, A Pahl, JM Gally, N Wild, Y Mantel, ... Nature Communications 12 (1), 1883, 2021 | 78 | 2021 |
| The time and place for nature in drug discovery RJ Young, SL Flitsch, M Grigalunas, PD Leeson, RJ Quinn, NJ Turner, ... Jacs Au 2 (11), 2400-2416, 2022 | 69 | 2022 |
| Pseudo-natural products and natural product-inspired methods in chemical biology and drug discovery M Grigalunas, A Burhop, A Christoforow, H Waldmann Current Opinion in Chemical Biology 56, 111-118, 2020 | 69 | 2020 |
| Ni-catalyzed alkenylation of ketone enolates under mild conditions: catalyst identification and optimization M Grigalunas, T Ankner, PO Norrby, O Wiest, P Helquist Journal of the American Chemical Society 137 (22), 7019-7022, 2015 | 62 | 2015 |
| Palladium-catalyzed alkenylation of ketone enolates under mild conditions M Grigalunas, T Ankner, PO Norrby, O Wiest, P Helquist Organic letters 16 (15), 3970-3973, 2014 | 43 | 2014 |
| 2-Hydroxypropyl-β-cyclodextrin is the active component in a triple combination formulation for treatment of Niemann-Pick C1 disease J Davidson, E Molitor, S Moores, SE Gale, K Subramanian, X Jiang, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2019 | 28 | 2019 |
| Spacial Score─ A Comprehensive Topological Indicator for Small-Molecule Complexity A Krzyzanowski, A Pahl, M Grigalunas, H Waldmann Journal of Medicinal Chemistry 66 (18), 12739-12750, 2023 | 24 | 2023 |
| Synthesis of Indofulvin Pseudo‐Natural Products Yields a New Autophagy Inhibitor Chemotype A Burhop, S Bag, M Grigalunas, S Woitalla, P Bodenbinder, L Brieger, ... Advanced Science 8 (19), 2102042, 2021 | 24 | 2021 |
| Identification of dihydroorotate dehydrogenase inhibitors using the cell painting assay B Schölermann, J Bonowski, M Grigalunas, A Burhop, Y Xie, JGF Hoock, ... ChemBioChem 23 (22), e202200475, 2022 | 20 | 2022 |
| Single-flask multicomponent synthesis of highly substituted α-pyrones via a sequential enolate arylation and alkenylation strategy M Grigalunas, O Wiest, P Helquist Organic letters 18 (21), 5724-5727, 2016 | 19 | 2016 |
| Single‐Flask Multicomponent Palladium‐Catalyzed α, γ‐Coupling of Ketone Enolates: Facile Preparation of Complex Carbon Scaffolds M Grigalunas, PO Norrby, O Wiest, P Helquist Angewandte Chemie International Edition 54 (40), 11822-11825, 2015 | 17 | 2015 |
| Dynamic catalytic highly enantioselective 1, 3‐dipolar cycloadditions O Yildirim, M Grigalunas, L Brieger, C Strohmann, AP Antonchick, ... Angewandte Chemie 133 (36), 20165-20173, 2021 | 16 | 2021 |
| The pseudo‐natural product rhonin targets RHOGDI M Akbarzadeh, J Flegel, S Patil, E Shang, R Narayan, M Buchholzer, ... Angewandte Chemie 134 (18), e202115193, 2022 | 14 | 2022 |
| Unprecedented combination of polyketide natural product fragments identifies the new hedgehog signaling pathway inhibitor grismonone M Grigalunas, S Patil, A Krzyzanowski, A Pahl, J Flegel, B Schölermann, ... Chemistry–A European Journal 28 (67), e202202164, 2022 | 11 | 2022 |
| Directed zincation or magnesiation of 2-and 4-pyrones and their derivatives DS Ziegler, L Klier, N Müller, K Karaghiosoff, P Knochel Synthesis 50 (22), 4383-4394, 2018 | 11 | 2018 |
| Inhibition of histone deacetylases 1, 2, and 3 enhances clearance of cholesterol accumulation in Niemann-Pick C1 fibroblasts DL Cruz, N Pipalia, S Mao, D Gadi, G Liu, M Grigalunas, M O’Neill, ... ACS Pharmacology & Translational Science 4 (3), 1136-1148, 2021 | 7 | 2021 |
| A divergent intermediate strategy yields biologically diverse pseudo-natural products S Bag, J Liu, S Patil, J Bonowski, S Koska, B Schölermann, R Zhang, ... Nature Chemistry, 1-14, 2024 | 6 | 2024 |
| A highly enantioselective intramolecular 1, 3-dipolar cycloaddition yields novel pseudo-natural product inhibitors of the Hedgehog signalling pathway J Liu, R Zhang, S Mallick, S Patil, C Wientjens, J Flegel, A Krupp, ... Chemical Science 14 (29), 7936-7943, 2023 | 6 | 2023 |
| Synthetic Matching of Complex Monoterpene Indole Alkaloid Chemical Space J Xie, A Pahl, A Krzyzanowski, A Krupp, J Liu, S Koska, B Schölermann, ... Angewandte Chemie 135 (48), e202310222, 2023 | 5 | 2023 |
