| Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases W Xu, H Yang, Y Liu, Y Yang, P Wang, SH Kim, S Ito, C Yang, P Wang, ... Cancer cell 19 (1), 17-30, 2011 | 3095 | 2011 |
| Regulation of cellular metabolism by protein lysine acetylation S Zhao, W Xu, W Jiang, W Yu, Y Lin, T Zhang, J Yao, L Zhou, Y Zeng, H Li, ... Science 327 (5968), 1000-1004, 2010 | 2096 | 2010 |
| Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1α S Zhao, Y Lin, W Xu, W Jiang, Z Zha, P Wang, W Yu, Z Li, L Gong, Y Peng, ... Science 324 (5924), 261-265, 2009 | 1408 | 2009 |
| Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux Q Wang, Y Zhang, C Yang, H Xiong, Y Lin, J Yao, H Li, L Xie, W Zhao, ... Science 327 (5968), 1004-1007, 2010 | 1131 | 2010 |
| Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors M Xiao, H Yang, W Xu, S Ma, H Lin, H Zhu, L Liu, Y Liu, C Yang, Y Xu, ... Genes & development 26 (12), 1326-1338, 2012 | 1125 | 2012 |
| TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway QY Lei, H Zhang, B Zhao, ZY Zha, F Bai, XH Pei, S Zhao, Y Xiong, ... Molecular and cellular biology 28 (7), 2426-2436, 2008 | 1036 | 2008 |
| TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition H Zhang, CY Liu, ZY Zha, B Zhao, J Yao, S Zhao, Y Xiong, QY Lei, ... Journal of biological chemistry 284 (20), 13355-13362, 2009 | 609 | 2009 |
| Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS Y Chen, J Zhang, Y Lin, Q Lei, KL Guan, S Zhao, Y Xiong EMBO reports 12 (6), 534-541, 2011 | 608 | 2011 |
| The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCFβ-TrCP E3 ligase CY Liu, ZY Zha, X Zhou, H Zhang, W Huang, D Zhao, T Li, SW Chan, ... Journal of Biological Chemistry 285 (48), 37159-37169, 2010 | 580 | 2010 |
| Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction WC Hallows, W Yu, BC Smith, MK Devires, JJ Ellinger, S Someya, ... Molecular cell 41 (2), 139-149, 2011 | 439 | 2011 |
| Acetylation regulates gluconeogenesis by promoting PEPCK1 degradation via recruiting the UBR5 ubiquitin ligase W Jiang, S Wang, M Xiao, Y Lin, L Zhou, Q Lei, Y Xiong, KL Guan, S Zhao Molecular cell 43 (1), 33-44, 2011 | 434 | 2011 |
| Metabolic reprogramming of cancer-associated fibroblasts by IDH3α downregulation D Zhang, Y Wang, Z Shi, J Liu, P Sun, X Hou, J Zhang, S Zhao, BP Zhou, ... Cell reports 10 (8), 1335-1348, 2015 | 327 | 2015 |
| An acetylation switch of the NLRP3 inflammasome regulates aging-associated chronic inflammation and insulin resistance M He, HH Chiang, H Luo, Z Zheng, Q Qiao, L Wang, M Tan, R Ohkubo, ... Cell metabolism 31 (3), 580-591. e5, 2020 | 272 | 2020 |
| Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT–mTORC1 activation P Zhang, D Wang, Y Zhao, S Ren, K Gao, Z Ye, S Wang, CW Pan, Y Zhu, ... Nature medicine 23 (9), 1055-1062, 2017 | 263 | 2017 |
| SIRT5 desuccinylates and activates pyruvate kinase M2 to block macrophage IL-1β production and to prevent DSS-induced colitis in mice F Wang, K Wang, W Xu, S Zhao, D Ye, Y Wang, Y Xu, L Zhou, Y Chu, ... Cell reports 19 (11), 2331-2344, 2017 | 254 | 2017 |
| RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis Z Yang, Y Wang, Y Zhang, X He, CQ Zhong, H Ni, X Chen, Y Liang, J Wu, ... Nature cell biology 20 (2), 186-197, 2018 | 227 | 2018 |
| Metabolic changes in cancer: beyond the Warburg effect W Wu, S Zhao Acta Biochim Biophys Sin 45 (1), 18-26, 2013 | 227 | 2013 |
| NADP+-IDH mutations promote hypersuccinylation that impairs mitochondria respiration and induces apoptosis resistance F Li, X He, D Ye, Y Lin, H Yu, C Yao, L Huang, J Zhang, F Wang, S Xu, ... Molecular cell 60 (4), 661-675, 2015 | 207 | 2015 |
| SIRT 3‐dependent GOT 2 acetylation status affects the malate–aspartate NADH shuttle activity and pancreatic tumor growth H Yang, L Zhou, Q Shi, Y Zhao, H Lin, M Zhang, S Zhao, Y Yang, ZQ Ling, ... The EMBO journal 34 (8), 1110-1125, 2015 | 195 | 2015 |
| PP1 cooperates with ASPP2 to dephosphorylate and activate TAZ CY Liu, X Lv, T Li, Y Xu, X Zhou, S Zhao, Y Xiong, QY Lei, KL Guan Journal of Biological Chemistry 286 (7), 5558-5566, 2011 | 156 | 2011 |
