The dual role of sirtuins in cancer L Bosch-Presegué, A Vaquero Genes & cancer 2 (6), 648-662, 2011 | 357 | 2011 |
Stabilization of Suv39H1 by SirT1 is part of oxidative stress response and ensures genome protection L Bosch-Presegué, H Raurell-Vila, A Marazuela-Duque, ... Molecular cell 42 (2), 210-223, 2011 | 150 | 2011 |
Sirtuin‐dependent epigenetic regulation in the maintenance of genome integrity L Bosch‐Presegué, A Vaquero The FEBS journal 282 (9), 1745-1767, 2015 | 131 | 2015 |
Sirtuins in stress response: guardians of the genome L Bosch-Presegue, A Vaquero Oncogene 33 (29), 3764-3775, 2014 | 114 | 2014 |
Mammalian HP1 isoforms have specific roles in heterochromatin structure and organization L Bosch-Presegue, H Raurell-Vila, JK Thackray, J González, C Casal, ... Cell reports 21 (8), 2048-2057, 2017 | 73 | 2017 |
SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway I Santos-Barriopedro, L Bosch-Presegué, A Marazuela-Duque, ... Nature communications 9 (1), 101, 2018 | 54 | 2018 |
Effect of dodecyl maltoside detergent on rhodopsin stability and function E Ramon, J Marron, L Del Valle, L Bosch, A Andrés, J Manyosa, P Garriga Vision research 43 (28), 3055-3061, 2003 | 44 | 2003 |
Structural and functional role of helices I and II in rhodopsin: A novel interplay evidenced by mutations at GLY-51 and GLY-89 in the transmembrane domain L Bosch, E Ramon, LJ Del Valle, P Garriga Journal of Biological Chemistry 278 (22), 20203-20209, 2003 | 38 | 2003 |
Critical role of electrostatic interactions of amino acids at the cytoplasmic region of helices 3 and 6 in rhodopsin conformational properties and activation E Ramon, A Cordomí, L Bosch, EY Zernii, II Senin, J Manyosa, ... Journal of Biological Chemistry 282 (19), 14272-14282, 2007 | 29 | 2007 |
An HP1 isoform-specific feedback mechanism regulates Suv39h1 activity under stress conditions H Raurell-Vila, L Bosch-Presegue, J Gonzalez, N Kane-Goldsmith, ... Epigenetics 12 (2), 166-175, 2017 | 28 | 2017 |
The histone demethylase PHF8 is a molecular safeguard of the IFNγ response E Asensio-Juan, R Fueyo, S Pappa, S Iacobucci, C Badosa, S Lois, ... Nucleic acids research 45 (7), 3800-3811, 2017 | 22 | 2017 |
Ca2+/recoverin dependent regulation of phosphorylation of the rhodopsin mutant R135L associated with retinitis pigmentosa II Senin, L Bosch, E Ramon, EY Zernii, J Manyosa, PP Philippov, ... Biochemical and biophysical research communications 349 (1), 345-352, 2006 | 18 | 2006 |
New prospects for drug discovery from structural studies of rhodopsin L Bosch, L Iarriccio, P Garriga Current pharmaceutical design 11 (17), 2243-2256, 2005 | 17 | 2005 |
Alterations in the photoactivation pathway of rhodopsin mutants associated with retinitis pigmentosa L Bosch‐Presegué, E Ramon, D Toledo, A Cordomí, P Garriga The FEBS journal 278 (9), 1493-1505, 2011 | 13 | 2011 |
Specific isomerization of rhodopsin-bound 11-cis-retinal to all-trans-retinal under thermal denaturation LJ Del Valle, E Ramon, L Bosch, J Manyosa, P Garriga Cellular and Molecular Life Sciences CMLS 60, 2532-2537, 2003 | 12 | 2003 |
Identification of soluble and membrane‐bound isoforms of porcine tumor necrosis factor receptor 2 M Uribe‐Herranz, SR Casinghino, L Bosch‐Presegué, WL Fodor, C Costa Xenotransplantation 18 (2), 131-146, 2011 | 8 | 2011 |
Hydrophobic amino acids at the cytoplasmic ends of helices 3 and 6 of rhodopsin conjointly modulate transducin activation L Bosch-Presegué, L Iarriccio, M Aguilà, D Toledo, E Ramon, A Cordomí, ... Archives of biochemistry and biophysics 506 (2), 142-149, 2011 | 7 | 2011 |
The dual role of sirtuins in cancer. Genes Cancer 2: 648–662 L Bosch-Presegué, A Vaquero | 7 | 2011 |
A methyl group at C7 of 11-cis-retinal allows chromophore formation but affects rhodopsin activation L Bosch, A Cordomí, M Domínguez, D Toledo, M Morillo, JJ Pérez, ... Vision research 46 (27), 4472-4481, 2006 | 5 | 2006 |
New insights into the molecular mechanism of rhodopsin retinitis pigmentosa from the biochemical and functional characterization of G90V, Y102H and I307N mutations MG Herrera-Hernández, N Razzaghi, P Fernandez-Gonzalez, ... Cellular and Molecular Life Sciences 79 (1), 58, 2022 | 4 | 2022 |