| Development of a Green and Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264) Part 1: Introduction and Process Overview H Ren, KM Maloney, K Basu, MJ Di Maso, GR Humphrey, F Peng, ... Organic Process Research & Development 24 (11), 2445-2452, 2020 | 30 | 2020 |
| Manufacturing process development for belzutifan, part 5: a streamlined fluorination–dynamic kinetic resolution process T Wang, EM Phillips, SM Dalby, E Sirota, S Axnanda, CS Shultz, P Patel, ... Organic Process Research & Development 26 (3), 543-550, 2021 | 28 | 2021 |
| Oxazole Synthesis by Sequential Asmic-Ester Condensations and Sulfanyl–Lithium Exchange–Trapping LG Mueller Jr, A Chao, E Alwedi, M Natrajan, FF Fleming Organic Letters 23 (4), 1500-1503, 2021 | 15 | 2021 |
| Asmic: an exceptional building block for isocyanide alkylations E Alwedi, JA Lujan-Montelongo, BR Pitta, A Chao, R Cortés-Mejía, ... Organic letters 20 (18), 5910-5913, 2018 | 15 | 2018 |
| Engineering Hydroxylase Activity, Selectivity, and Stability for a Scalable Concise Synthesis of a Key Intermediate to Belzutifan WL Cheung‐Lee, JN Kolev, JA McIntosh, AA Gil, W Pan, L Xiao, ... Angewandte Chemie International Edition 63 (13), e202316133, 2024 | 14 | 2024 |
| Chain Extension of Boronic Esters with Lithiooxiranes Generated by Sulfoxide–Metal Exchange–Stereocontrolled Access to 2/2, 2/3, and 3/3 Vicinal Diols and Related Compounds E Alwedi, LN Zakharov, PR Blakemore European Journal of Organic Chemistry 2014 (30), 6643-6648, 2014 | 14 | 2014 |
| Development of a Green and Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264). Part 5: Completion of the API Free Base via a Direct Chlorosulfonylation Process MJ Di Maso, H Ren, SW Zhang, W Liu, R Desmond, E Alwedi, ... Organic Process Research & Development 24 (11), 2491-2497, 2020 | 12 | 2020 |
| Asmic Isocyanide‐Nitrile Isomerization‐Alkylations E Alwedi Eur.J.Org.Chem 29, 4644-4648, 2019 | 11 | 2019 |
| Isocyanide Purification: C-2 Silica Cleans Up a Dirty Little Secret FFF Allen Chao, Embarek Alwedi synthesis 51 (06), 2019 | 11 | 2019 |
| Synthesis and Antibacterial Activity of Certain Fused Azoles and Oxazinones AM El‐Saghier, EF Alwedi, NM Fawzy Journal of Heterocyclic Chemistry 49 (3), 664-668, 2012 | 8 | 2012 |
| Development of a Green and Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264). Part 6: Development of an Improved Commercial Salt Formation Process KM Maloney, SW Zhang, AE Mohan, AY Lee, P Larpent, H Ren, ... Organic Process Research & Development 24 (11), 2498-2504, 2020 | 6 | 2020 |
| Evolution of a Green and Sustainable Manufacturing Process for Belzutifan: Part 5─ Chemoenzymatic Diastereoselective Fluorination/DKR SD McCann, SH Dubina, B Kosjek, E Alwedi, T Behre, SA Burgess, ... Organic Process Research & Development 28 (2), 441-450, 2024 | 4 | 2024 |
| Evolution of a Green and Sustainable Manufacturing Process for Belzutifan: Part 6─ Development of a Nucleophilic Aromatic Substitution in Water DN Le, TJ Wright, E Alwedi, C Hartmanshenn, H Li, JP McMullen, ... Organic Process Research & Development 28 (2), 451-459, 2024 | 4 | 2024 |
| Synthesis of the Isocyanide Building Block Asmic, anisylsulfanylmethylisocyanide E Alwedi, B Altundas, A Chao, ZL Ziminsky, M Natrayan, FF Fleming Organic Syntheses 98 (98), 147-170, 2021 | 4 | 2021 |
| Dearomatization of aromatic asmic isocyanides to complex cyclohexadienes B Altundas, E Alwedi, Z Song, AR Gogoi, R Dykstra, O Gutierrez, ... Nature communications 13 (1), 6444, 2022 | 3 | 2022 |
| Development of a derivatization RP-HPLC method for determination of sulfuryl chloride in chlorosulfonic acid for gefapixant citrate manufacture C Huang, S Song, W Liu, P Parganiha, P Zhuang, S Lohani, E Alwedi, ... Journal of Pharmaceutical and Biomedical Analysis 215, 114752, 2022 | 3 | 2022 |
| One-step synthesis of imidazoles from Asmic (anisylsulfanylmethyl isocyanide) LG Mueller, A Chao, E AlWedi, FF Fleming Beilstein journal of organic chemistry 17 (1), 1499-1502, 2021 | 3 | 2021 |
| Polar-Radical Cyclization Cascades with Magnesiated Nitriles S Bolgunas, E Paleo, E Alwedi, Y Wei, TM Keller, FF Fleming Organic letters 25 (19), 3512-3516, 2023 | 2 | 2023 |
| Exploration of the utility of CF3+ as a reagent for chemical ionisation reaction mass spectrometry RS Blake, SA Ouheda, EF Alwedi, PS Monks International Journal of Mass Spectrometry 421, 224-233, 2017 | 2 | 2017 |
| Development of a Green and Sustainable Manufacturing Process for a Key Intermediate to Nemtabrutinib (MK-1026): Sequential Deprotonation–Lithiation as a Batch–Flow Process DAL Otte, RT Larson, E Alwedi, T Armiger, Y Chen, CK Chung, J Corry, ... Organic Process Research & Development, 2024 | | 2024 |
