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Martin Lange
Martin Lange
Head of Translational Research
在 nuvisan.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors
M Schütte, T Risch, N Abdavi-Azar, K Boehnke, D Schumacher, M Keil, ...
Nature communications 8 (1), 14262, 2017
3102017
Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity
C Ballaré, M Lange, A Lapinaite, GM Martin, L Morey, G Pascual, R Liefke, ...
Nature structural & molecular biology 19 (12), 1257-1265, 2012
2732012
Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex
M Lange, B Kaynak, UB Forster, M Tönjes, JJ Fischer, C Grimm, ...
Genes & development 22 (17), 2370-2384, 2008
2692008
The cardiac transcription network modulated by Gata4, Mef2a, Nkx2. 5, Srf, histone modifications, and microRNAs
J Schlesinger, M Schueler, M Grunert, JJ Fischer, Q Zhang, T Krueger, ...
PLoS genetics 7 (2), e1001313, 2011
2552011
Assay establishment and validation of a high-throughput screening platform for three-dimensional patient-derived colon cancer organoid cultures
K Boehnke, PW Iversen, D Schumacher, MJ Lallena, R Haro, J Amat, ...
Journal of biomolecular screening 21 (9), 931-941, 2016
1512016
Simultaneous inhibition of PI3Kδ and PI3Kα induces ABC-DLBCL regression by blocking BCR-dependent and-independent activation of NF-κB and AKT
J Paul, M Soujon, AM Wengner, S Zitzmann-Kolbe, A Sturz, K Haike, ...
Cancer cell 31 (1), 64-78, 2017
1482017
Non-canonical hedgehog signaling is a positive regulator of the WNT pathway and is required for the survival of colon cancer stem cells
JL Regan, D Schumacher, S Staudte, A Steffen, J Haybaeck, U Keilholz, ...
Cell reports 21 (10), 2813-2828, 2017
1262017
Characterization of TBX20 in human hearts and its regulation by TFAP2
S Hammer, M Toenjes, M Lange, JJ Fischer, I Dunkel, S Mebus, ...
Journal of cellular biochemistry 104 (3), 1022-1033, 2008
712008
Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer
SM Dieter, C Siegl, PL Codó, M Huerta, AL Ostermann-Parucha, E Schulz, ...
Cell reports 36 (3), 2021
512021
Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase
CW Garvie, X Wu, M Papanastasiou, S Lee, J Fuller, GR Schnitzler, ...
Nature Communications 12 (1), 4375, 2021
512021
Depression of transcription and translation during daily torpor in the Djungarian hamster (Phodopus sungorus)
M Berriel Diaz, M Lange, G Heldmaier, M Klingenspor
Journal of Comparative Physiology B 174, 495-502, 2004
392004
A tyrosine-rich domain within homeodomain transcription factor Nkx2-5 is an essential element in the early cardiac transcriptional regulatory machinery
DA Elliott, MJ Solloway, N Wise, C Biben, MW Costa, MB Furtado, ...
Oxford University Press for The Company of Biologists Limited 133 (7), 1311-1322, 2006
382006
Indazolecarboxamides, processes for their preparation, pharmaceutical preparations comprising them and their use for producing medicaments
U Bothe, H Siebeneicher, N Schmidt, A Rotgeri, U Bömer, S Ring, ...
US Patent 9,951,086, 2018
352018
PDE5 inhibition eliminates cancer stem cells via induction of PKA signaling
S Klutzny, A Anurin, B Nicke, JL Regan, M Lange, L Schulze, K Parczyk, ...
Cell Death & Disease 9 (2), 192, 2018
342018
Copanlisib synergizes with conventional and targeted agents including venetoclax in B-and T-cell lymphoma models
C Tarantelli, M Lange, E Gaudio, L Cascione, F Spriano, I Kwee, ...
Blood advances 4 (5), 819-829, 2020
332020
Identification of small molecules that modulate mutant p53 condensation
C Lemos, L Schulze, J Weiske, H Meyer, N Braeuer, N Barak, ...
Iscience 23 (9), 2020
322020
PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3
HR Chung, C Xu, A Fuchs, A Mund, M Lange, H Staege, T Schubert, ...
Elife 5, e10607, 2016
322016
Combinatorial assembly and function of chromatin regulatory complexes
M Lange, S Demajo, P Jain, L Di Croce
Epigenomics 3 (5), 567-580, 2011
312011
Setting and resetting of epigenetic marks in malignant transformation and development
H Richly, M Lange, E Simboeck, L Di Croce
Bioessays 32 (8), 669-679, 2010
262010
The Polycomb-associated factor PHF19 controls hematopoietic stem cell state and differentiation
P Vizán, A Gutiérrez, I Espejo, M García-Montolio, M Lange, A Carretero, ...
Science advances 6 (32), eabb2745, 2020
252020
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