Structural and functional characterization of two alpha-synuclein strains L Bousset, L Pieri, G Ruiz-Arlandis, J Gath, PH Jensen, B Habenstein, ... Nature communications 4 (1), 2575, 2013 | 914 | 2013 |
DJ-1 and α-synuclein in human cerebrospinal fluid as biomarkers of Parkinson’s disease Z Hong, M Shi, KA Chung, JF Quinn, ER Peskind, D Galasko, J Jankovic, ... Brain 133 (3), 713-726, 2010 | 735 | 2010 |
Binding of α-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation PH Jensen, MS Nielsen, R Jakes, CG Dotti, M Goedert Journal of Biological Chemistry 273 (41), 26292-26294, 1998 | 692 | 1998 |
Purified alpha 2-macroglobulin receptor/LDL receptor-related protein binds urokinase. plasminogen activator inhibitor type-1 complex. Evidence that the alpha 2-macroglobulin … A Nykjær, CM Petersen, B Møller, PH Jensen, SK Moestrup, TL Holtet, ... Journal of Biological Chemistry 267 (21), 14543-14546, 1992 | 604 | 1992 |
Proteasomal inhibition by α-synuclein filaments and oligomers E Lindersson, R Beedholm, P Højrup, T Moos, WP Gai, KB Hendil, ... Journal of Biological Chemistry 279 (13), 12924-12934, 2004 | 512 | 2004 |
α-Synuclein binds to tau and stimulates the protein kinase A-catalyzed tau phosphorylation of serine residues 262 and 356 PH Jensen, H Hager, MS Nielsen, P Højrup, J Gliemann, R Jakes Journal of Biological Chemistry 274 (36), 25481-25489, 1999 | 469 | 1999 |
Accumulation of toxic α-synuclein oligomer within endoplasmic reticulum occurs in α-synucleinopathy in vivo E Colla, PH Jensen, O Pletnikova, JC Troncoso, C Glabe, MK Lee Journal of Neuroscience 32 (10), 3301-3305, 2012 | 376 | 2012 |
In situ and in vitro study of colocalization and segregation of α-synuclein, ubiquitin, and lipids in Lewy bodies WP Gai, HX Yuan, XQ Li, JTH Power, PC Blumbergs, PH Jensen Experimental neurology 166 (2), 324-333, 2000 | 320 | 2000 |
Phosphorylated α-synuclein in Parkinson’s disease Y Wang, M Shi, KA Chung, CP Zabetian, JB Leverenz, D Berg, K Srulijes, ... Science translational medicine 4 (121), 121ra20-121ra20, 2012 | 316 | 2012 |
Evidence for bidirectional and trans-synaptic parasympathetic and sympathetic propagation of alpha-synuclein in rats N Van Den Berge, N Ferreira, H Gram, TW Mikkelsen, AKO Alstrup, ... Acta neuropathologica 138 (4), 535-550, 2019 | 272 | 2019 |
Detection of elevated levels of soluble α-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies KE Paleologou, CL Kragh, DMA Mann, SA Salem, R Al-Shami, D Allsop, ... Brain 132 (4), 1093-1101, 2009 | 254 | 2009 |
Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo E Rockenstein, S Nuber, CR Overk, K Ubhi, M Mante, C Patrick, A Adame, ... Brain 137 (5), 1496-1513, 2014 | 252 | 2014 |
Tubulin polymerization-promoting protein (TPPP/p25α) promotes unconventional secretion of α-synuclein through exophagy by impairing autophagosome-lysosome fusion P Ejlerskov, I Rasmussen, TT Nielsen, AL Bergström, Y Tohyama, ... Journal of Biological Chemistry 288 (24), 17313-17335, 2013 | 239 | 2013 |
α-Synuclein redistributes to neuromelanin lipid in the substantia nigra early in Parkinson's disease GM Halliday, A Ophof, M Broe, PH Jensen, E Kettle, H Fedorow, ... Brain 128 (11), 2654-2664, 2005 | 238 | 2005 |
How Epigallocatechin Gallate Can Inhibit α-Synuclein Oligomer Toxicity in Vitro♦ N Lorenzen, SB Nielsen, Y Yoshimura, BS Vad, CB Andersen, C Betzer, ... Journal of Biological Chemistry 289 (31), 21299-21310, 2014 | 219 | 2014 |
Calcium (II) selectively induces α‐synuclein annular oligomers via interaction with the C‐terminal domain R Lowe, DL Pountney, PH Jensen, WP Gai, NH Voelcker Protein Science 13 (12), 3245-3252, 2004 | 214 | 2004 |
Ca2+ binding to α-synuclein regulates ligand binding and oligomerization MS Nielsen, H Vorum, E Lindersson, PH Jensen Journal of Biological Chemistry 276 (25), 22680-22684, 2001 | 207 | 2001 |
p25α stimulates α-synuclein aggregation and is co-localized with aggregated α-synuclein in α-synucleinopathies E Lindersson, D Lundvig, C Petersen, P Madsen, JR Nyengaard, ... Journal of Biological Chemistry 280 (7), 5703-5715, 2005 | 205 | 2005 |
p25α relocalizes in oligodendroglia from myelin to cytoplasmic inclusions in multiple system atrophy YJC Song, DMS Lundvig, Y Huang, WP Gai, PC Blumbergs, P Højrup, ... The American journal of pathology 171 (4), 1291-1303, 2007 | 200 | 2007 |
Binding of Aβ to α- and β-synucleins: identification of segments in α-synuclein/NAC precursor that bind Aβ and NAC PH JENSEN, P HØJRUP, H HAGER, MS NIELSEN, L JACOBSEN, ... Biochemical Journal 323 (2), 539-546, 1997 | 196 | 1997 |