Copper-containing catalytic amyloids promote phosphoester hydrolysis and tandem reactions Z Lengyel, CM Rufo, YS Moroz, OV Makhlynets, IV Korendovych ACS catalysis 8 (1), 59-62, 2018 | 87 | 2018 |
The Sigma-2 Receptor/TMEM97, PGRMC1, and LDL Receptor complex are responsible for the cellular uptake of Aβ42 and its protein aggregates A Riad, Z Lengyel-Zhand, C Zeng, CC Weng, VMY Lee, JQ Trojanowski, ... Molec Neurobiol, 3803–3813, 2020 | 58 | 2020 |
Nine-residue peptide self-assembles in the presence of silver to produce a self-healing, cytocompatible, antimicrobial hydrogel A D’Souza, JH Yoon, H Beaman, P Gosavi, Z Lengyel-Zhand, A Sternisha, ... ACS applied materials & interfaces 12 (14), 17091-17099, 2020 | 47 | 2020 |
Identification of a nanomolar affinity α-synuclein fibril imaging probe by ultra-high throughput in silico screening JJ Ferrie, Z Lengyel-Zhand, B Janssen, MG Lougee, S Giannakoulias, ... Chemical science 11 (47), 12746-12754, 2020 | 36 | 2020 |
Synthesis and characterization of high affinity fluorogenic α-synuclein probes Z Lengyel-Zhand, JJ Ferrie, B Janssen, CJ Hsieh, T Graham, K Xu, ... Chemical Communications 56 (24), 3567-3570, 2020 | 36 | 2020 |
Minimalist de Novo Design of Protein Catalysts LR Marshall, O Zozulia, Z Lengyel-Zhand, IV Korendovych ACS catalysis 9 (10), 9265-9275, 2019 | 33 | 2019 |
Catalytic nanoassemblies formed by short peptides promote highly enantioselective transfer hydrogenation MA Dolan, PN Basa, O Zozulia, Z Lengyel, R Lebl, EM Kohn, ... ACS nano 13 (8), 9292-9297, 2019 | 29 | 2019 |
The effect of conjugation on antitumor activity of vindoline derivatives with octaarginine, a cell‐penetrating peptide Z Bánóczi, A Keglevich, I Szabó, I Ranđelović, Z Hegedüs, FL Regenbach, ... Journal of Peptide Science 24 (10), e3118, 2018 | 20 | 2018 |
Synthesis and in vitro antitumor effect of new vindoline derivatives coupled with amino acid esters P Keglevich, L Hazai, Á Gorka-Kereskényi, L Péter, J Gyenese, Z Lengyel, ... Heterocycles 87 (11), 2299-2317, 2013 | 18 | 2013 |
Poly (ADP-ribose) interacts with phosphorylated α-synuclein in post mortem PD samples LN Puentes, Z Lengyel-Zhand, JY Lee, CJ Hsieh, ME Schneider Jr, ... Frontiers in Aging Neuroscience 13, 704041, 2021 | 16 | 2021 |
Evaluation of a low-toxicity PARP inhibitor as a neuroprotective agent for Parkinson’s disease LN Puentes, Z Lengyel-Zhand, SW Reilly, RH Mach Molecular Neurobiology 58, 3641-3652, 2021 | 14 | 2021 |
Synergistic interactions are prevalent in catalytic amyloids LR Marshall, M Jayachandran, Z Lengyel‐Zhand, CM Rufo, A Kriews, ... ChemBioChem 21 (18), 2611-2614, 2020 | 12 | 2020 |
Uno Ferro, a de novo designed protein, binds transition metals with high affinity and stabilizes semiquinone radical anion JH Yoon, AV Kulesha, Z Lengyel‐Zhand, AN Volkov, JJ Rempillo, ... Chemistry–A European Journal 25 (67), 15252-15256, 2019 | 11 | 2019 |
Preparation and screening of catalytic amyloid assemblies Z Lengyel, CM Rufo, IV Korendovych Peptide Self-Assembly: Methods and Protocols, 261-270, 2018 | 11 | 2018 |
Functional tuning of the catalytic residue pKa in a de novo designed esterase K Hiebler, Z Lengyel, CA Castañeda, OV Makhlynets Proteins: Structure, Function, and Bioinformatics 85 (9), 1656-1665, 2017 | 11 | 2017 |
Poly (ADP-ribose) induces α-synuclein aggregation in neuronal-like cells and interacts with phosphorylated α-synuclein in post mortem PD samples LN Puentes, Z Lengyel-Zhand, JY Lee, CJ Hsieh, ME Schneider Jr, ... bioRxiv, 2020.04. 08.032250, 2020 | 7 | 2020 |
PARkinson's: From cellular mechanisms to potential therapeutics Z Lengyel-Zhand, LN Puentes, RH Mach Pharmacology & therapeutics 230, 107968, 2022 | 5 | 2022 |
Covalent linkage and macrocylization preserve and enhance synergistic interactions in catalytic amyloids I Korendovych, Z Lengyel-Zhand, LR Marshall, M Jung, M Jayachandran, ... ChemBioChem, 2020 | 4* | 2020 |
Kemp eliminases of the AlleyCat family possess high substrate promiscuity EA Caselle, JH Yoon, S Bhattacharya, JJL Rempillo, Z Lengyel, ... ChemCatChem 11 (5), 1425-1430, 2019 | 4 | 2019 |
A Novel Brain PET Radiotracer for Imaging Alpha Synuclein Fibrils in Multiple System Atrophy HY Kim, WK Chia, CJ Hsieh, D Saturnino Guarino, TJA Graham, ... Journal of Medicinal Chemistry 66 (17), 12185-12202, 2023 | 2 | 2023 |