Efficacy and epigenetic interactions of novel DNA hypomethylating agent guadecitabine (SGI-110) in preclinical models of hepatocellular carcinoma S Jueliger, J Lyons, S Cannito, I Pata, P Pata, M Shkolnaya, O Lo Re, ... Epigenetics 11 (10), 709-720, 2016 | 79 | 2016 |
Gut dysbiosis and adaptive immune response in diet-induced obesity vs. systemic inflammation J Pindjakova, C Sartini, O Lo Re, F Rappa, B Coupe, B Lelouvier, ... Frontiers in microbiology 8, 1157, 2017 | 76 | 2017 |
Induction of cancer cell stemness by depletion of macrohistone H2A1 in hepatocellular carcinoma O Lo Re, C Fusilli, F Rappa, M Van Haele, J Douet, J Pindjakova, ... Hepatology 67 (2), 636-650, 2018 | 66 | 2018 |
Fasting inhibits hepatic stellate cells activation and potentiates anti‐cancer activity of Sorafenib in hepatocellular cancer cells O Lo Re, C Panebianco, S Porto, C Cervi, F Rappa, S Di Biase, ... Journal of cellular physiology 233 (2), 1202-1212, 2018 | 59 | 2018 |
Mild exacerbation of obesity-and age-dependent liver disease progression by senolytic cocktail dasatinib+ quercetin M Raffaele, K Kovacovicova, J Frohlich, O Lo Re, S Giallongo, JA Oben, ... Cell Communication and Signaling 19, 1-9, 2021 | 44 | 2021 |
Histone variant macroH2A1 rewires carbohydrate and lipid metabolism of hepatocellular carcinoma cells towards cancer stem cells. VM Lo Re O, Douet J, Buschbeck M, Fusilli C, Pazienza V, Panebianco C ... Epigenetics., 2018 | 44 | 2018 |
Epigenetic remodelling in human hepatocellular carcinoma MR Braghini, O Lo Re, I Romito, MG Fernandez-Barrena, B Barbaro, ... Journal of Experimental & Clinical Cancer Research 41 (1), 107, 2022 | 40 | 2022 |
Histone MacroH2A1: a chromatin point of intersection between fasting, senescence and cellular regeneration O Lo Re, M Vinciguerra Genes 8 (12), 367, 2017 | 34 | 2017 |
Loss of histone macroH2A1 in hepatocellular carcinoma cells promotes paracrine-mediated chemoresistance and CD4+ CD25+ FoxP3+ regulatory T cells activation OL Re, T Mazza, S Giallongo, P Sanna, F Rappa, TV Luong, GL Volti, ... Theranostics 10 (2), 910, 2020 | 31 | 2020 |
Independent effects of hypertension and obesity on left ventricular mass and geometry: evidence from the Cardiovision 2030 study A Maugeri, J Hruskova, J Jakubik, M Barchitta, O Lo Re, S Kunzova, ... Journal of Clinical Medicine 8 (3), 370, 2019 | 27 | 2019 |
Circulating histone signature of human lean metabolic-associated fatty liver disease (MAFLD) D Buzova, A Maugeri, A Liguori, C Napodano, O Lo Re, J Oben, A Alisi, ... Clinical epigenetics 12, 1-15, 2020 | 25 | 2020 |
Deficiency and haploinsufficiency of histone macroH2A1.1 in mice recapitulate hematopoietic defects of human myelodysplastic syndrome. VM Bereshchenko O, Lo Re O, Nikulenkov F, Flamini S, Kotaskova J, Mazza T ... Clin Epigenetics., 2019 | 23 | 2019 |
Loss of macroH2A1 decreases mitochondrial metabolism and reduces the aggressiveness of uveal melanoma cells S Giallongo, M Di Rosa, R Caltabiano, L Longhitano, M Reibaldi, ... Aging (Albany NY) 12 (10), 9745, 2020 | 21 | 2020 |
Macro histone variants: emerging rheostats of gastrointestinal cancers S Giallongo, O Lo Re, M Vinciguerra Cancers 11 (5), 676, 2019 | 20 | 2019 |
Redox and epigenetics in human pluripotent stem cells differentiation S Giallongo, D Rehakova, M Raffaele, O Lo Re, I Koutna, M Vinciguerra Antioxidants & redox signaling 34 (4), 335-349, 2021 | 18 | 2021 |
Obesity-induced nucleosome release predicts poor cardio-metabolic health O Lo Re, A Maugeri, J Hruskova, J Jakubik, J Kucera, J Bienertova-Vasku, ... Clinical Epigenetics 12, 1-14, 2020 | 18 | 2020 |
Nociceptin/orphanin FQ opioid receptor (NOP) selective ligand MCOPPB links anxiolytic and senolytic effects M Raffaele, K Kovacovicova, T Biagini, O Lo Re, J Frohlich, S Giallongo, ... GeroScience, 1-21, 2022 | 16 | 2022 |
A lipidomic signature complements stemness features acquisition in liver cancer cells IM Rivas Serna, I Romito, A Maugeri, O Lo Re, S Giallongo, G Mazzoccoli, ... International Journal of Molecular Sciences 21 (22), 8452, 2020 | 16 | 2020 |
Systemic depletion of histone macroH2A1. 1 boosts hippocampal synaptic plasticity and social behavior in mice V Chiodi, MR Domenici, T Biagini, R De Simone, AM Tartaglione, ... The FASEB Journal 35 (8), e21793, 2021 | 13 | 2021 |
Histone variant macroH2A1. 1 enhances nonhomologous end joining-dependent DNA double-strand-break repair and reprogramming efficiency of human iPSCs S Giallongo, D Řeháková, T Biagini, O Lo Re, P Raina, G Lochmanová, ... Stem Cells 40 (1), 35-48, 2022 | 12 | 2022 |