Macrophage P2X4 receptors augment bacterial killing and protect against sepsis B Csóka, ZH Németh, I Szabó, DL Davies, ZV Varga, J Pálóczi, S Falzoni, ... JCI insight 3 (11), 2018 | 103 | 2018 |
Evidence that ethanol acts on a target in Loop 2 of the extracellular domain of α1 glycine receptors DK Crawford, JR Trudell, EJ Bertaccini, K Li, DL Davies, RL Alkana Journal of neurochemistry 102 (6), 2097-2109, 2007 | 85 | 2007 |
Ethanol differentially affects ATP-gated P2X3 and P2X4 receptor subtypes expressed in Xenopus oocytes DL Davies, AA Kochegarov, ST Kuo, AA Kulkarni, JJ Woodward, BF King, ... Neuropharmacology 49 (2), 243-253, 2005 | 80 | 2005 |
Implication of the purinergic system in alcohol use disorders L Asatryan, HW Nam, MR Lee, MM Thakkar, M Saeed Dar, DL Davies, ... Alcoholism: Clinical and Experimental Research 35 (4), 584-594, 2011 | 78 | 2011 |
Ivermectin antagonizes ethanol inhibition in purinergic P2X4 receptors L Asatryan, M Popova, D Perkins, JR Trudell, RL Alkana, DL Davies Journal of Pharmacology and Experimental Therapeutics 334 (3), 720-728, 2010 | 75 | 2010 |
Ivermectin reduces alcohol intake and preference in mice MM Yardley, L Wyatt, S Khoja, L Asatryan, MJ Ramaker, DA Finn, ... Neuropharmacology 63 (2), 190-201, 2012 | 73 | 2012 |
Ethanol sensitivity in ATP‐gated P2X receptors is subunit dependent DL Davies, TK Machu, Y Guo, RL Alkana Alcoholism: Clinical and Experimental Research 26 (6), 773-778, 2002 | 73 | 2002 |
P2X4 receptors (P2X4Rs) represent a novel target for the development of drugs to prevent and/or treat alcohol use disorders KM Franklin, L Asatryan, MW Jakowec, JR Trudell, RL Bell, DL Davies Frontiers in neuroscience 8, 176, 2014 | 72 | 2014 |
Alcohol‐binding sites in distinct brain proteins: the quest for atomic level resolution RJ Howard, PA Slesinger, DL Davies, J Das, JR Trudell, RA Harris Alcoholism: Clinical and Experimental Research 35 (9), 1561-1573, 2011 | 72 | 2011 |
Dihydromyricetin protects the liver via changes in lipid metabolism and enhanced ethanol metabolism J Silva, X Yu, R Moradian, C Folk, MH Spatz, P Kim, AA Bhatti, DL Davies, ... Alcoholism: Clinical and Experimental Research 44 (5), 1046-1060, 2020 | 66 | 2020 |
Structural models of ligand‐gated ion channels: Sites of action for anesthetics and ethanol RW Olsen, GD Li, M Wallner, JR Trudell, EJ Bertaccini, E Lindahl, ... Alcoholism: Clinical and Experimental Research 38 (3), 595-603, 2014 | 66 | 2014 |
Molecular targets and mechanisms for ethanol action in glycine receptors DI Perkins, JR Trudell, DK Crawford, RL Alkana, DL Davies Pharmacology & therapeutics 127 (1), 53-65, 2010 | 64 | 2010 |
P2X4 receptor reporter mice: sparse brain expression and feeding-related presynaptic facilitation in the arcuate nucleus J Xu, AM Bernstein, A Wong, XH Lu, S Khoja, XW Yang, DL Davies, ... Journal of Neuroscience 36 (34), 8902-8920, 2016 | 61 | 2016 |
Sociocommunicative and sensorimotor impairments in male P2X4-deficient mice LR Wyatt, SC Godar, S Khoja, MW Jakowec, RL Alkana, M Bortolato, ... Neuropsychopharmacology 38 (10), 1993-2002, 2013 | 61 | 2013 |
Social isolation induces neuroinflammation and microglia overactivation, while dihydromyricetin prevents and improves them AJ Al Omran, AS Shao, S Watanabe, Z Zhang, J Zhang, C Xue, ... Journal of Neuroinflammation 19 (1), 2, 2022 | 57 | 2022 |
Contribution of P2X4 receptors to ethanol intake in male C57BL/6 mice LR Wyatt, DA Finn, S Khoja, MM Yardley, L Asatryan, RL Alkana, ... Neurochemical research 39, 1127-1139, 2014 | 56 | 2014 |
Pharmacological insights into the role of P2X4 receptors in behavioural regulation: lessons from ivermectin M Bortolato, MM Yardley, S Khoja, SC Godar, L Asatryan, DA Finn, ... International Journal of Neuropsychopharmacology 16 (5), 1059-1070, 2013 | 55 | 2013 |
Ethanol is a fast channel inhibitor of P2X4 receptors O Ostrovskaya, L Asatryan, L Wyatt, M Popova, K Li, RW Peoples, ... Journal of Pharmacology and Experimental Therapeutics 337 (1), 171-179, 2011 | 54 | 2011 |
Role of purinergic P2X4 receptors in regulating striatal dopamine homeostasis and dependent behaviors S Khoja, V Shah, D Garcia, L Asatryan, MW Jakowec, DL Davies Journal of neurochemistry 139 (1), 134-148, 2016 | 52 | 2016 |
Loop 2 structure in glycine and GABAA receptors plays a key role in determining ethanol sensitivity DI Perkins, JR Trudell, DK Crawford, L Asatryan, RL Alkana, DL Davies Journal of Biological Chemistry 284 (40), 27304-27314, 2009 | 51 | 2009 |