Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue Y Imaizumi, Y Okada, W Akamatsu, M Koike, N Kuzumaki, H Hayakawa, ... Molecular brain 5, 1-13, 2012 | 418 | 2012 |
A human Dravet syndrome model from patient induced pluripotent stem cells N Higurashi, T Uchida, C Lossin, Y Misumi, Y Okada, W Akamatsu, ... Molecular brain 6, 1-12, 2013 | 151 | 2013 |
Generation of human melanocytes from induced pluripotent stem cells S Ohta, Y Imaizumi, Y Okada, W Akamatsu, R Kuwahara, M Ohyama, ... PloS one 6 (1), e16182, 2011 | 150 | 2011 |
Modeling human neurological disorders with induced pluripotent stem cells Y Imaizumi, H Okano Journal of neurochemistry 129 (3), 388-399, 2014 | 133 | 2014 |
T-type calcium channels determine the vulnerability of dopaminergic neurons to mitochondrial stress in familial Parkinson disease Y Tabata, Y Imaizumi, M Sugawara, T Andoh-Noda, S Banno, MC Chai, ... Stem cell reports 11 (5), 1171-1184, 2018 | 89 | 2018 |
Pre-clinical characterisation of E2814, a high-affinity antibody targeting the microtubule-binding repeat domain of tau for passive immunotherapy in Alzheimer’s disease M Roberts, I Sevastou, Y Imaizumi, K Mistry, S Talma, M Dey, J Gartlon, ... Acta neuropathologica communications 8, 1-24, 2020 | 86 | 2020 |
Human Induced Pluripotent Stem Cell–Derived Ectodermal Precursor Cells Contribute to Hair Follicle Morphogenesis In Vivo O Veraitch, T Kobayashi, Y Imaizumi, W Akamatsu, T Sasaki, S Yamanaka, ... Journal of Investigative Dermatology 133 (6), 1479-1488, 2013 | 74 | 2013 |
I2020T mutant LRRK2 iPSC-derived neurons in the Sagamihara family exhibit increased Tau phosphorylation through the AKT/GSK-3β signaling pathway E Ohta, T Nihira, A Uchino, Y Imaizumi, Y Okada, W Akamatsu, ... Human molecular genetics 24 (17), 4879-4900, 2015 | 73 | 2015 |
Expression and function of galectin-1 in adult neural stem cells M Sakaguchi, Y Imaizumi, H Okano Cellular and molecular life sciences 64, 1254-1258, 2007 | 43 | 2007 |
Regulation of adult neural progenitor cells by Galectin‐1/β1 Integrin interaction M Sakaguchi, Y Imaizumi, T Shingo, H Tada, K Hayama, O Yamada, ... Journal of neurochemistry 113 (6), 1516-1524, 2010 | 38 | 2010 |
Establishment of a human neuronal network assessment system by using a human neuron/astrocyte co-culture derived from fetal neural stem/progenitor cells K Fukushima, Y Miura, K Sawada, K Yamazaki, M Ito Journal of biomolecular screening 21 (1), 54-64, 2016 | 34 | 2016 |
Galectin-1 is expressed in early-type neural progenitor cells and down-regulates neurogenesis in the adult hippocampus Y Imaizumi, M Sakaguchi, T Morishita, M Ito, F Poirier, K Sawamoto, ... Molecular brain 4, 1-10, 2011 | 33 | 2011 |
Impaired spatial and contextual memory formation in galectin-1 deficient mice M Sakaguchi, M Arruda-Carvalho, NH Kang, Y Imaizumi, F Poirier, ... Molecular brain 4, 1-10, 2011 | 31 | 2011 |
Generation of human melanocytes from induced pluripotent stem cells S Ohta, Y Imaizumi, W Akamatsu, H Okano, Y Kawakami Skin Stem Cells: Methods and Protocols, 193-215, 2013 | 24 | 2013 |
Characterization of human hippocampal neural stem/progenitor cells and their application to physiologically relevant assays for multiple ionotropic glutamate receptors K Fukushima, Y Tabata, Y Imaizumi, N Kohmura, M Sugawara, K Sawada, ... Journal of biomolecular screening 19 (8), 1174-1184, 2014 | 9 | 2014 |
Functional Comparison of Neuronal Cells Differentiated from Human Induced Pluripotent Stem Cell–Derived Neural Stem Cells under Different Oxygen and Medium Conditions K Yamazaki, K Fukushima, M Sugawara, Y Tabata, Y Imaizumi, Y Ishihara, ... Journal of Biomolecular Screening 21 (10), 1054-1064, 2016 | 7 | 2016 |
Neurovascular coupling in primary auditory cortex investigated with voltage-sensitive dye imaging and laser-Doppler flowmetry H Kameyama, K Masamoto, Y Imaizumi, T Omura, T Katura, A Maki, ... Brain research 1244, 82-88, 2008 | 5 | 2008 |
P4‐695: E2814: A NOVEL ANTI‐TAU THERAPEUTIC ANTIBODY FOR ALZHEIMER'S DISEASE M Roberts, I Sevastou, Y Imaizumi, K Mistry, S Talma, M Dey, J Gartlon, ... Alzheimer's & Dementia 15, P1598-P1598, 2019 | 1 | 2019 |
I2020T LRRK2 iPSC-derived neurons in the Sagamihara family exhibit increased Tau phosphorylation through the AKT/GSK-3beta signaling pathway E Ohta, T Nihira, A Uchino, Y Imaizumi, Y Okada, W Akamatsu, ... Parkinsonism & Related Disorders 22, e167, 2016 | | 2016 |
Galectin-1 is expressed in early type neural progenitor cells and down-regulates neurogenesis in the adult hippocampus Y Imaizumi, M Sakaguchi, T Morishita, M Ito, F Poirier, K Sawamoto, ... Neuroscience Research, e365, 2010 | | 2010 |