Evolution and classification of the CRISPR–Cas systems KS Makarova, DH Haft, R Barrangou, SJJ Brouns, E Charpentier, ... Nature Reviews Microbiology 9 (6), 467-477, 2011 | 3116 | 2011 |
An updated evolutionary classification of CRISPR–Cas systems KS Makarova, YI Wolf, OS Alkhnbashi, F Costa, SA Shah, SJ Saunders, ... Nature Reviews Microbiology 13 (11), 722-736, 2015 | 2591 | 2015 |
Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants KS Makarova, YI Wolf, J Iranzo, SA Shmakov, OS Alkhnbashi, SJJ Brouns, ... Nature Reviews Microbiology 18 (2), 67-83, 2020 | 1447 | 2020 |
Genome-wide analysis of substrate specificities of the Escherichia coli haloacid dehalogenase-like phosphatase family E Kuznetsova, M Proudfoot, CF Gonzalez, G Brown, MV Omelchenko, ... Journal of Biological Chemistry 281 (47), 36149-36161, 2006 | 332 | 2006 |
A dual function of the CRISPR–Cas system in bacterial antivirus immunity and DNA repair M Babu, N Beloglazova, R Flick, C Graham, T Skarina, B Nocek, ... Molecular microbiology 79 (2), 484-502, 2011 | 331 | 2011 |
In situ proteolysis for protein crystallization and structure determination A Dong, X Xu, AM Edwards Nature methods 4 (12), 1019-1021, 2007 | 286 | 2007 |
A novel family of sequence-specific endoribonucleases associated with the clustered regularly interspaced short palindromic repeats N Beloglazova, G Brown, MD Zimmerman, M Proudfoot, KS Makarova, ... Journal of Biological Chemistry 283 (29), 20361-20371, 2008 | 255 | 2008 |
Nuclease activity of the human SAMHD1 protein implicated in the Aicardi-Goutieres syndrome and HIV-1 restriction N Beloglazova, R Flick, A Tchigvintsev, G Brown, A Popovic, B Nocek, ... Journal of Biological Chemistry 288 (12), 8101-8110, 2013 | 246 | 2013 |
Heavy metal removal by bioaccumulation using genetically engineered microorganisms P Diep, R Mahadevan, AF Yakunin Frontiers in bioengineering and biotechnology 6, 157, 2018 | 211 | 2018 |
Enzyme genomics: Application of general enzymatic screens to discover new enzymes E Kuznetsova, M Proudfoot, SA Sanders, J Reinking, A Savchenko, ... FEMS microbiology reviews 29 (2), 263-279, 2005 | 187 | 2005 |
Structure and activity of the Cas3 HD nuclease MJ0384, an effector enzyme of the CRISPR interference N Beloglazova, P Petit, R Flick, G Brown, A Savchenko, AF Yakunin The EMBO journal 30 (22), 4616-4627, 2011 | 163 | 2011 |
Structural insight into the mechanism of c-di-GMP hydrolysis by EAL domain phosphodiesterases A Tchigvintsev, X Xu, A Singer, C Chang, G Brown, M Proudfoot, H Cui, ... Journal of molecular biology 402 (3), 524-538, 2010 | 149 | 2010 |
SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia C Schneider, T Oellerich, HM Baldauf, SM Schwarz, D Thomas, R Flick, ... Nature medicine 23 (2), 250-255, 2017 | 142 | 2017 |
Molecular basis of formaldehyde detoxification: characterization of two S-formylglutathione hydrolases from Escherichia coli, FrmB and YeiG CF Gonzalez, M Proudfoot, G Brown, Y Korniyenko, H Mori, ... Journal of Biological Chemistry 281 (20), 14514-14522, 2006 | 140 | 2006 |
Integrating structure, bioinformatics, and enzymology to discover function: BioH, a new carboxylesterase from Escherichia coli R Sanishvili, AF Yakunin, RA Laskowski, T Skarina, E Evdokimova, ... Journal of Biological Chemistry 278 (28), 26039-26045, 2003 | 139 | 2003 |
Riboneogenesis in yeast MF Clasquin, E Melamud, A Singer, JR Gooding, X Xu, A Dong, H Cui, ... Cell 145 (6), 969-980, 2011 | 138 | 2011 |
Genome sequence and functional genomic analysis of the oil-degrading bacterium Oleispira antarctica M Kube, TN Chernikova, Y Al-Ramahi, A Beloqui, N Lopez-Cortez, ... Nature communications 4 (1), 2156, 2013 | 137 | 2013 |
Polyphosphate-dependent synthesis of ATP and ADP by the family-2 polyphosphate kinases in bacteria B Nocek, S Kochinyan, M Proudfoot, G Brown, E Evdokimova, J Osipiuk, ... Proceedings of the National Academy of Sciences 105 (46), 17730-17735, 2008 | 136 | 2008 |
Functional and structural characterization of four glutaminases from Escherichia coli and Bacillus subtilis G Brown, A Singer, M Proudfoot, T Skarina, Y Kim, C Chang, ... Biochemistry 47 (21), 5724-5735, 2008 | 124 | 2008 |
Role of GlnB and GlnK in ammonium control of both nitrogenase systems in the phototrophic bacterium Rhodobacter capsulatus T Drepper, S Groß, AF Yakunin, PC Hallenbeck, B Masepohl, W Klipp Microbiology 149 (8), 2203-2212, 2003 | 121 | 2003 |