Leptin receptor signaling in midbrain dopamine neurons regulates feeding JD Hommel, R Trinko, RM Sears, D Georgescu, ZW Liu, XB Gao, ... neuron 51 (6), 801-810, 2006 | 1084 | 2006 |
Local gene knockdown in the brain using viral-mediated RNA interference JD Hommel, RM Sears, D Georgescu, DL Simmons, RJ DiLeone Nature medicine 9 (12), 1539-1544, 2003 | 454 | 2003 |
The hypothalamic neuropeptide melanin-concentrating hormone acts in the nucleus accumbens to modulate feeding behavior and forced-swim performance D Georgescu, RM Sears, JD Hommel, M Barrot, CA Bolanos, DJ Marsh, ... Journal of Neuroscience 25 (11), 2933-2940, 2005 | 355 | 2005 |
The birth, death and resurrection of avoidance: a reconceptualization of a troubled paradigm JE LeDoux, J Moscarello, R Sears, V Campese Molecular psychiatry 22 (1), 24-36, 2017 | 351 | 2017 |
Orexin/hypocretin system modulates amygdala-dependent threat learning through the locus coeruleus RM Sears, AE Fink, MB Wigestrand, CR Farb, L De Lecea, JE LeDoux Proceedings of the National Academy of Sciences 110 (50), 20260-20265, 2013 | 227 | 2013 |
Active avoidance requires a serial basal amygdala to nucleus accumbens shell circuit F Ramirez, JM Moscarello, JE LeDoux, RM Sears Journal of Neuroscience 35 (8), 3470-3477, 2015 | 207 | 2015 |
Regulation of nucleus accumbens activity by the hypothalamic neuropeptide melanin-concentrating hormone RM Sears, RJ Liu, NS Narayanan, R Sharf, MF Yeckel, M Laubach, ... Journal of Neuroscience 30 (24), 8263-8273, 2010 | 113 | 2010 |
Active vs. reactive threat responding is associated with differential c-Fos expression in specific regions of amygdala and prefrontal cortex RCR Martinez, N Gupta, G Lázaro-Muñoz, RM Sears, S Kim, ... Learning & memory 20 (8), 446-452, 2013 | 101 | 2013 |
Neural mechanisms underlying obesity and drug addiction R Trinko, RM Sears, DJ Guarnieri, RJ DiLeone Physiology & behavior 91 (5), 499-505, 2007 | 95 | 2007 |
Serotonin (5-HT) 5-HT2A Receptor (5-HT2AR):5-HT2CR Imbalance in Medial Prefrontal Cortex Associates with Motor Impulsivity NC Anastasio, SJ Stutz, LHL Fink, SE Swinford-Jackson, RM Sears, ... ACS chemical neuroscience 6 (7), 1248-1258, 2015 | 91 | 2015 |
Functional status of the serotonin 5-HT2C receptor (5-HT2CR) drives interlocked phenotypes that precipitate relapse-like behaviors in cocaine dependence NC Anastasio, SJ Stutz, RG Fox, RM Sears, RB Emeson, RJ DiLeone, ... Neuropsychopharmacology 39 (2), 360-372, 2014 | 87 | 2014 |
β-Adrenergic receptors regulate the acquisition and consolidation phases of aversive memory formation through distinct, temporally regulated signaling pathways HC Schiff, JP Johansen, M Hou, DEA Bush, EK Smith, JAE Klein, ... Neuropsychopharmacology 42 (4), 895-903, 2017 | 61 | 2017 |
A brainstem-central amygdala circuit underlies defensive responses to learned threats Y Gu, WT Piper, LA Branigan, EM Vazey, G Aston-Jones, L Lin, ... Molecular psychiatry 25 (3), 640-654, 2020 | 58 | 2020 |
Molecular mechanisms of threat learning in the lateral nucleus of the amygdala RM Sears, HC Schiff, JE LeDoux Progress in Molecular Biology and Translational Science 122, 263-304, 2014 | 58 | 2014 |
Axon TRAP reveals learning-associated alterations in cortical axonal mRNAs in the lateral amygdala LE Ostroff, E Santini, R Sears, Z Deane, RN Kanadia, JE LeDoux, ... Elife 8, e51607, 2019 | 56 | 2019 |
Chronic loss of melanin-concentrating hormone affects motivational aspects of feeding in the rat JD Mul, SE La Fleur, PW Toonen, A Afrasiab-Middelman, R Binnekade, ... PloS one 6 (5), e19600, 2011 | 54 | 2011 |
The neural foundations of reaction and action in aversive motivation VD Campese, RM Sears, JM Moscarello, L Diaz-Mataix, CK Cain, ... Behavioral neuroscience of motivation, 171-195, 2016 | 43 | 2016 |
Erk1/2 mediates leptin receptor signaling in the ventral tegmental area R Trinko, G Gan, XB Gao, RM Sears, DJ Guarnieri, RJ DiLeone PloS one 6 (11), e27180, 2011 | 40 | 2011 |
Characterization of the amplificatory effect of norepinephrine in the acquisition of Pavlovian threat associations L Díaz-Mataix, WT Piper, HC Schiff, CH Roberts, VD Campese, RM Sears, ... Learning & memory 24 (9), 432-439, 2017 | 32 | 2017 |
Primary auditory cortex regulates threat memory specificity MB Wigestrand, HC Schiff, M Fyhn, JE LeDoux, RM Sears Learning & Memory 24 (1), 55-58, 2017 | 29 | 2017 |