Downstream processing of lentiviral vectors: releasing bottlenecks V Bandeira, C Peixoto, AF Rodrigues, PE Cruz, PM Alves, AS Coroadinha, ... Human Gene Therapy, Part B: Methods 23 (4), 255-263, 2012 | 106 | 2012 |
A new generation of retroviral producer cells: predictable and stable virus production by Flp-mediated site-specific integration of retroviral vectors R Schucht, AS Coroadinha, MA Zanta-Boussif, E Verhoeyen, ... Molecular Therapy 14 (2), 285-292, 2006 | 90 | 2006 |
Viral vaccines and their manufacturing cell substrates: New trends and designs in modern vaccinology AF Rodrigues, HR Soares, MR Guerreiro, PM Alves, AS Coroadinha Biotechnology journal 10 (9), 1329-1344, 2015 | 88 | 2015 |
The use of recombinase mediated cassette exchange in retroviral vector producer cell lines: predictability and efficiency by transgene exchange AS Coroadinha, R Schucht, L Gama-Norton, D Wirth, H Hauser, ... Journal of biotechnology 124 (2), 457-468, 2006 | 88 | 2006 |
New low-toxicity cholinium-based ionic liquids with perfluoroalkanoate anions for aqueous biphasic system implementation DJS Patinha, LC Tome, C Florindo, HR Soares, AS Coroadinha, ... ACS Sustainable Chemistry & Engineering 4 (5), 2670-2679, 2016 | 64 | 2016 |
Progress and perspectives in the development of lentiviral vector producer cells MV Ferreira, ET Cabral, AS Coroadinha Biotechnology journal 16 (1), 2000017, 2021 | 61 | 2021 |
LentiPro26: novel stable cell lines for constitutive lentiviral vector production HA Tomás, AF Rodrigues, MJT Carrondo, AS Coroadinha Scientific reports 8 (1), 5271, 2018 | 58 | 2018 |
Bioprocess development for canine adenovirus type 2 vectors P Fernandes, C Peixoto, VM Santiago, EJ Kremer, AS Coroadinha, ... Gene therapy 20 (4), 353-360, 2013 | 56 | 2013 |
Bioactive transparent films based on polysaccharides and cholinium carboxylate ionic liquids LC Tomé, NHCS Silva, HR Soares, AS Coroadinha, P Sadocco, ... Green Chemistry 17 (8), 4291-4299, 2015 | 51 | 2015 |
Stabilization of gammaretroviral and lentiviral vectors: from production to gene transfer M Carmo, A Alves, AF Rodrigues, AS Coroadinha, MJT Carrondo, ... The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2009 | 50 | 2009 |
Effect of osmotic pressure on the production of retroviral vectors: Enhancement in vector stability AS Coroadinha, AC Silva, E Pires, A Coelho, PM Alves, MJT Carrondo Biotechnology and bioengineering 94 (2), 322-329, 2006 | 48 | 2006 |
Robust expansion of human pluripotent stem cells: integration of bioprocess design with transcriptomic and metabolomic characterization MM Silva, AF Rodrigues, C Correia, MFQ Sousa, C Brito, AS Coroadinha, ... Stem cells translational medicine 4 (7), 731-742, 2015 | 45 | 2015 |
Production of retroviral and lentiviral gene therapy vectors: challenges in the manufacturing of lipid enveloped virus AF Rodrigues, PM Alves, AS Coroadinha Viral gene therapy, 15-40, 2011 | 44 | 2011 |
MicroRNA-146a controls functional plasticity in γδ T cells by targeting NOD1 N Schmolka, PH Papotto, PV Romero, T Amado, FJ Enguita, A Amorim, ... Science immunology 3 (23), eaao1392, 2018 | 43 | 2018 |
Flipase‐mediated cassette exchange in Sf9 insect cells for stable gene expression F Fernandes, J Vidigal, MM Dias, KLJ Prather, AS Coroadinha, ... Biotechnology and bioengineering 109 (11), 2836-2844, 2012 | 42 | 2012 |
Production of retroviral vectors AS Coroadinha, L Gama-Norton, AI Amaral, H Hauser, PM Alves, PE Cruz Current gene therapy 10 (6), 456-473, 2010 | 42 | 2010 |
Quantitation of MLV-based retroviral vectors using real-time RT-PCR M Carmo, C Peixoto, AS Coroadinha, PM Alves, PE Cruz, MJT Carrondo Journal of virological methods 119 (2), 115-119, 2004 | 41 | 2004 |
Lentiviral gene therapy vectors: challenges and future directions HA Tomás, AF Rodrigues, PM Alves, AS Coroadinha Gene therapy-tools and potential applications, 2013 | 40 | 2013 |
Retroviral vector production under serum deprivation: The role of lipids AF Rodrigues, M Carmo, PM Alves, AS Coroadinha Biotechnology and bioengineering 104 (6), 1171-1181, 2009 | 39 | 2009 |
Effect of medium sugar source on the production of retroviral vectors for gene therapy AS Coroadinha, J Ribeiro, A Roldao, PE Cruz, PM Alves, OW Merten, ... Biotechnology and bioengineering 94 (1), 24-36, 2006 | 39 | 2006 |